Molecular Dynamic Simulation Study on Replacement of Methane Hydrates with Carbon Dioxide Under Different Temperatures, Pressures, and Concentrations of Ethylene Glycol.

In order to alleviate the world energy resources crisis, the research and development of natural gas hydrates has a very important economic value and strategic significance. The CH-CO replacement method can not only achieve geological storage of carbon dioxide but also more effectively mine natural gas hydrates. Based on molecular dynamics theory and the properties of natural gas hydrates, this paper delves into the replacement of methane hydrate with carbon dioxide under different temperatures, pressures, and concentrations of ethylene glycol (EG).

Metformin relieves H/R-induced cardiomyocyte injury through miR-19a/ACSL axis - possible therapeutic target for myocardial I/R injury.

This study proposed to investigate the function of miR-19a/ACSL axis in hypoxia/reoxygenation (H/R)-induced myocardial injury and determine whether metformin exerts its protective effect via miR-19a/ACSL axis. Firstly, bioinformatics analysis of data from Gene Expression Omnibus (GEO) database indicated that miR-19a was downregulated in patients with myocardial infarction (MI) compared to that in control group. H/R model was constructed with AC16 cells in vitro.

Retrospective study of the prognostic significance of neutrophil-to-lymphocyte ratio for postsurgical outcomes of patients with endometrial carcinoma.

Objective: To evaluate the significance of postoperative inflammatory system response markers in predicting the prognosis of patients with endometrial cancer undergoing surgery.

Methods: The present retrospective study included patients who underwent surgical treatment for pathology-confirmed endometrial cancer between January 1, 2007, and June 30, 2013, at the Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing, China. Potential prognostic factors were investigated by Cox proportional hazards analysis and survival rates were compared using Kaplan-Meier analyses.

[Bone density in osteoarthritic femoral heads: quantitative assessment by histomorphologic and histomorphometric analysis].

Objective: To determine whether bone density is related to osteoarthritis and to compare osteoarthritis with osteoporotic fracture of the femoral neck.

Methods: All 165 femoral heads removed at joint replacement surgery were divided into 4 groups according to radiographic features of hip (osteophytes, subchondral sclerosis, cysts and femoral head deformity). The individual femoral head was divided into 5 zones histologically.