Cyclopenta[]benzopyran Derivatives and Limonoids from with Cytotoxic and Anti-DENV Activity.

Eighteen cyclopenta[]benzopyran derivatives (- and -) and 10 limonoids (- and -) were identified from , including 10 undescribed compounds (-), all of which were identified by analysis of spectroscopic data, electronic circular dichroism calculations, and X-ray crystallography studies. Nine compounds displayed significant cytotoxic activity against three cancer cells, with IC values of 3-900 nM. Sixteen compounds demonstrated potent antiviral activity on the dengue virus, with selectivity index values between 13.

UPLC-MS-MS Determination of Dihydrocodeine in Human Plasma and Its Application to a Pharmacokinetic Study.

A sensitive and rapid ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS-MS) method was developed to determine dihydrocodeine (DHC) in human plasma using diazepam as the internal standard (IS). Sample preparation was accomplished through a liquid-liquid extraction procedure with ethyl acetate. The analyte and IS were separated on an Acquity UPLC BEH C18 column (2.

Determination of kurarinone in rat plasma by UPLC-MS/MS.

A sensitive and rapid ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method was developed to determine kurarinone in rat plasma using chlorzoxazone as the internal standard (IS). Sample preparation was accomplished through a liquid-liquid extraction procedure with ethyl acetate to 0.2 mL plasma sample.

UPLC-MS/MS method for determination of avicularin in rat plasma and its application to a pharmacokinetic study.

A rapid, sensitive and selective ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) was developed and validated for the determination and pharmacokinetic investigation of avicularin in rat plasma. Sample preparation was accomplished through a simple one-step deproteinization procedure with 0.2 mL of acetonitrile-methanol (9:1, v/v) to a 0.

[Chlorophyll content and net photosynthetic rate of Machilus pauhoi and M. leptophylla].

By using SPAD-502 chlorophyll meter, LI-6400 portable photosynthesis system, and spectrophotometer, the leaf SPAD value, net photosynthetic rate (Pn), and chlorophyll (a + b) content (Ct) of 3-year-old Machilus pauhoi and M. leptophylla seedlings were measured, and the relationships of SPAD value with Pn and Ct were analyzed. The M.