Synopsis of recent research by authors named "Jian-Fan Chen"
- Jian-Fan Chen's recent research primarily focuses on understanding the mechanisms underlying chromosome alignment and segregation during cell division, particularly emphasizing the role of the kinesin-7 motor protein CENP-E in maintaining genomic stability.
- Another significant study investigates the predictive value of CRMP4 promoter hypermethylation in prostate cancer, identifying its potential as a biomarker for determining the likelihood of disease progression to a higher Gleason Score.
- Chen's earlier work includes evaluating adenosine receptor interactions, revealing complex pharmacological effects of adenosine A(2A) receptor agonists in the context of cerebral cortex receptor predominance, highlighting the nuances of receptor binding and pharmacology.