Publications by authors named "Jian-Cheng Shen"
Article Synopsis
- A study analyzed the genetic diversity of 8 indigenous chicken breeds in Sichuan using 30 selected microsatellite markers, revealing that 24 markers were highly polymorphic and effective for assessing genetic relationships.
- The mean heterozygosity across these breeds was above 0.5, with the Luning chicken showing the highest at 0.681, suggesting significant genetic diversity likely influenced by geographic isolation.
- The genetic relationships among the chicken breeds, as illustrated by an UPGMA tree, indicated distinct groupings based on their breeding history and geographic origin, underscoring the genetic diversity within this population.
To explore the mechanisms underlying the pro-apoptotic effects of the synthetic retinoid N-4-(hydroxyphenyl)retinamide (4-HPR) on LNCaP human prostate cancer cells, we used the differential display-polymerase chain reaction (DD-PCR) technique to identify 4-HPR-responsive genes. RNA extracted from LNCaP cells that had been treated for 24 h with 4-HPR at a dose (2.5 microM) optimal for apoptosis induction was used for DD-PCR analysis using random primers.
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