New lignans from .

A new lignan phyllanins A () and a lignan phyllanins B () for which the absolute configuration was determined for the first time, along with four known lignans (-) were isolated from the branch and leaf extracts of . Their planar structures were mainly determined by a combination of 1D and 2D NMR, HRESIMS spectral analyses, and the absolute configurations of the compounds and were established by DFT GIAO C NMR and electronic circular dichroism (ECD) calculations. In addition, all these six lignans were firstly tested for the antibacterial activities against MRSA, , , and .

Three new metabolites from the endophyte T2-10.

One new cyclopeptide, cyclo-(-Trp--Phe--Phe) (), one new 2-pyridone derivative, fusarone A (), and one new natural indole derivative, ethyl 3-indoleacetate (), along with six known compounds were isolated from the endophytic fungus T2-10. The planar structures of three new compounds were identified by spectral methods including 1D and 2D NMR techniques, and the absolute configuration of compound was elucidated by Marfey-MS method. In addition, all compounds were evaluated for their cytotoxic and antibacterial activities .

Pseudocercones A-C, three new polyketide derivatives from the endophytic fungus sp. TSS-1.

Chemical investigation of an EtOAc extract of the endophytic fungus sp. TSS-1 led to the isolation of three new polyketide derivatives, including one benzophenon derivative (), two spirocyclic polyketides ( and ), along with four known compounds (, , and ). Their structures and the absolute configurations were characterized by means of NMR, HRESIMS, C NMR and theoretical electronic circular dichroism calculations.

Lignans and phenolic constituents from Oliver.

Two new lignans, noreucol A () and (+)-epicycloolivil (), along with seven known compounds () were isolated from the aqueous extract of Oliver. Compound was a new norlignan and was an epimer at C-7 of (+)-cycloolivil (). Their structures were elucidated by spectroscopic methods, and the absolute configurations of new compounds were determined by conformational analysis and DFT theoretic electronic circular dichroism spectra calculations.

New cytotoxic biflavones from .

Three new biflavones, apigenin-(3',8″)-chrysin (), (2)-2,3-Dihydroametoflavone 5,4'-dimethyl ether (), and (2)-5″,7″-Dihydroxy-2″-phenoxychromonyl-(4'″,3')-naringenin (), together with seven known biflavones () were isolated from the 75% EtOH extract of . The structures of new compounds were established by application of spectroscopic methods, including 1D and 2D NMR, HRMS, and CD measurements. In addition, all new compounds were evaluated for their cytotoxic potential against three human cancer cell lines A549, MCF-7, and SMMC-7721 .

[Studies on flavonoid glycosides of Sarcandra glabra].

Objective: To in vestigate the chemical constituents of Sarcandra glabra and obtain a more comprehensive understanding on its effective components.

Method: The constituents were isolated by various column chromatographic method and their structures were elucidated by physico-chemical properties and spectroscopic analysis.

Result: Five flavonoid glycosides were isolated and identified as kaempferol-3-O-beta-D-glucuronide (1), quercetin-3-O-alpha-D-glucuronide (2), quercetin-3-O-beta-D-glucuronopyranoside methyl ester (3), 5, 7, 4'-trihydroxy-8-C-beta-D-glucopyranosyl flavanone (4), neoastilbin (5), 5-O-caffeoylquinic acid methyl ester (6), 3, 4-dihydroxybenzoic acid (7), isofraxidin (8).

[Studies on constituents of Oldenlandia diffusa].

Objective: To investigate the chemical constituents of Oldenlandia diffusa.

Method: The column chromatography with polyamide Sephadex LH -20, silica gel as packing materials and HPLC, were used to separate and purify the chemical components. The structures were elucidated on the basis of physicochemical properties and spectral data.

[Water-soluble chemical constituents of Swertia davidi Franch].

Aim: To study the active constituents of Swertia davidi Franch.

Methods: Column chromatographies on silica gel, Sephadex LH-20 and Diaion-201 et al. were used to isolate and purify the chemical components.