Immunomodulatory activity of a fructooligosaccharide isolated from burdock roots.

A novel burdock fructooligosaccharide (BFO-1) was extracted from fresh burdock roots. In our study, we found that BFO-1 possessed immunoenhancing activity and . The proliferation activities of splenocytes were significantly stimulated at a BFO-1 dose of 1000 μg ml ( < 0.

Effect of Sevoflurane Anesthesia on Brain Is Mediated by lncRNA HOTAIR.

Postoperative cognitive dysfunction in elderly patients has been related to neurodegenerative disorders and mortality. Sevoflurane anesthesia has been implicated in both postoperative cognitive dysfunction and neurotoxicity. Given the advantages of using inhaled anesthetics like sevoflurane, it is important to understand how their usage results in neurotoxicity and subsequently devise ways to circumvent or attenuate the anesthetic-mediated induction in neurotoxicity.

Mechanisms underlying the antiapoptotic and anti-inflammatory effects of monotropein in hydrogen peroxide-treated osteoblasts.

Monotropein, the primary iridoid glycoside isolated from Morindacitrifolia, has been previously reported to possess potent antioxidant and antiosteoporotic properties. However, there is no direct evidence correlating the antiosteoporotic effect of monotropein with its observed antioxidant capacity, and the molecular mechanisms involved in mediating these processes remain unclear. Therefore, the aim of the present study was to investigate the protective effects of monotropein against oxidative stress in osteoblasts and the mechanisms involved in mediating this process.

Curculigoside regulates proliferation, differentiation, and pro-inflammatory cytokines levels in dexamethasone-induced rat calvarial osteoblasts.

Background: Curculigoside (CCG), one of the main bioactive phenolic compounds isolated from the rhizome of Curculigo orchioides Gaertn., is reported to prevent bone loss in ovariectomized rats. However, the underlying molecular mechanisms are largely unknown.

[Analysis on heavy metal pollution in major seafoods from Zhoushan Fishery, China].

Objective: Through reviewing data on surveys, tested materials especially on lead in Zhoushan fisheries, with ground lead, cadmium and methyl-mercury were analyzed and evaluated.

Methods: According to the distribution of Zhoushan fisheries, we randomly selected a certain number of Zhoushan seafood as research objects from four counties or districts. Different kinds of seafood would include sea fish, seawater crustaceans, seawater soft-bodied animals and sea algae.

[Identification of genotype III Japanese encephalitis virus isolated in Zhejiang province].

Objective: To investigate the molecular characteristics and genotype of Japanese encephalitis virus (JEV) found in vector mosquitoes in Zhejiang province from 1982 to 1983.

Methods: A total of 3188 mosquitoes were collected in Dinghai district and Yiwu city in Zhejiang province, during year 1982 and 1983. The virus was isolated by C6/36 cell, and then identified by hemagglutination inhibition test.

[Infection and physico-chemical characteristics of Anisakis among marine fish caught in Zhoushan Fishery].

Objective: To study the rates of infection and physicochemical characteristics of the third stage Anisakis simplex larvae among marine fish caught in Zhoushan Fishery.

Methods: Fish were dissected to detect Anisakis larvae and identified morphologically. The survival tolerance of the third stage Anisakis simplex larvae in various medium, anthelmintic drug, temperature were studied in laboratory.

[A case-control study on the relationship between nutrition and gastric cancer in islanders].

Objective: To study the association between nutritional factors and gastric cancer in islanders.

Methods: A population-based case-control study on diet and gastric cancer was carried out in Zhoushan islands, China. 103 cases of gastric cancer newly diagnosed in 2001 and 133 controls frequency-matched by age, sex, and islands of residence among residents in Zhoushan were included in the study.

[Study on the relationship between smoking, alcohol intake and hyperlipidemia in fishermen].

Objective: To identify the relationship between smoking, alcohol intake and hyperlipidemia in fishermen.

Methods: 115 fishermen were randomly recruited and divided into case and control groups according to the result of blood lipoprotein. A questionnaire was used to record general information and the history of smoking and alcohol intake.

[A comparative study on iodine nutritional status of adult islanders in Zhoushan].

Objective: To measure the iodine nutritional status on adult islanders and to evaluate the advantages and disadvantages of iodized salt prophylactic programs.

Methods: A comparative study was carried out in 8 rural townships selected from Dinghai (iodized salt district) and Daishan (non-iodized salt district) of Zhoushan islands by random sampling method. Mann-Whitney test was used to compare the urinary iodine concentration and dietary iodine intake of the two groups.

Tetrodotoxin-associated snail poisoning in Zhoushan: a 25-year retrospective analysis.

Outbreaks of paralytic snail poisoning have recently occurred in Asia, especially in China. The epidemiological characteristics of this disease from an outbreak in Zhoushan City, China, were recorded. Forty-two outbreaks of paralytic snail poisoning, involving 309 cases of illness, occurred from 1977 to 2001.