Efficacy and safety of dietary polyphenol administration as assessed by hormonal, glycolipid metabolism, inflammation and oxidative stress parameters in patients with PCOS: a meta-analysis and systematic review.

Background: The current knowledge about the efficacy and safety of dietary polyphenol administration in patients with polycystic ovarian syndrome (PCOS) is divergent.

Objective: To evaluate the pooled efficacy and safety of dietary polyphenol administration in the treatment of patients with PCOS.

Methods: The pubmed, Embase, Scopus, Cochrane Library, and Web of Science databases were searched for randomized controlled trials (RCTs) of dietary polyphenol administration for the treatment of PCOS.

Carbon nanofiber coated ionic crystal architecture withconfinement effect for high-performance microwave absorption along with high-efficiency water harvesting from air.

Water is considered an effective microwave absorber due to its high transmittance and frequency-dispersive dielectric constant, yet it is challenging to form it into a stable state as an absorber. Herein, we developed a water-containing microwave absorber using chemical vapor deposition (CVD), namely, the bifunctional carbon/NaCl multi-interfaces hybrid with excellent water harvesting and microwave absorption performance. Carbon/NaCl exhibits remarkable water harvesting abilities from air, exceeding 210 % of its weight in 12 h.

Therapeutic effects and molecular mechanisms of quercetin in gynecological disorders.

Quercetin is a representative flavonoid that is widely present in fruits, herbs, and vegetables. It is also an important active core component in traditional Chinese medicines. As an important flavonoid, quercetin has various properties and exerts antioxidant, anti-inflammatory, and cardioprotective effects.

Robust Piezoelectricity with Spontaneous Polarization in Monolayer Tellurene and Multilayer Tellurium Film at Room Temperature for Reliable Memory.

Robust neuromorphic computing in the Big Data era calls for long-term stable crossbar-array memory cells; however, the elemental segregation in the switch unit and memory unit that inevitably occurs upon cycling breaks the compositional and structural stability, making the whole memory cell a failure. Searching for a novel material without segregation that can be used for both switch and memory units is the major concern to fabricate robust and reliable nonvolatile cross-array memory cells. Tellurium (Te) is found recently to be the only peculiar material without segregation for switching, but the memory function has not been demonstrated yet.

Atomic-Scale Layer-by-Layer Deposition of FeSiAl@ZnO@AlO Hybrid with Threshold Anti-Corrosion and Ultra-High Microwave Absorption Properties in Low-Frequency Bands.

Developing highly efficient magnetic microwave absorbers (MAs) is crucial, and yet challenging for anti-corrosion properties in extremely humid and salt-induced foggy environments. Herein, a dual-oxide shell of ZnO/AlO as a robust barrier to FeSiAl core is introduced to mitigate corrosion resistance. The FeSiAl@ZnO@AlO layer by layer hybrid structure is realized with atomic-scale precision through the atomic layer deposition technique.

Defect-Enhanced Electromagnetic Wave Absorption Property of Hierarchical Graphite Capsules@Helical Carbon Nanotube Hybrid Nanocomposites.

Development of high-performance materials for electromagnetic wave absorption has attracted extensive interest, but it still remains a huge challenge especially in reducing density and lowering filler loading. Herein, a hierarchical all-carbon nanostructure is rationally designed as follows: the defect-rich hollow graphite capsules (GCs) controlled by the size/density of ZnO templates are synthesized on the surface of helical carbon nanotubes (HCNTs) to form a hybrid nanocomposite, denoted as GCs@HCNTs. As a result, the GCs@HCNTs demonstrate a strong and wide absorption performance with a very low filler loading of 10 wt %.

Nitrogen-Doped Oxygenated Molybdenum Phosphide as an Efficient Electrocatalyst for Hydrogen Evolution in Alkaline Media.

Phosphides of transition metals (TMPs) are a developing class of materials for hydrogen evolution reaction (HER) as an alternative to expensive noble metals to produce clean energy. Herein, the nitrogen-doped molybdenum oxide (MoO) is developed via a facile and simple hydrothermal method, followed by annealing in the N atmosphere and phosphorization to form a nitrogen-doped oxygenated molybdenum phosphide (N-MoP) sphere-shaped structure. The developed N-doped phosphide structure depicts enhanced HER activity by reaching a current density of 10 mA cm at a very low overpotential of only 87 mV, which is much better than annealed nitrogen-doped molybdenum oxide (A-MoO) 138 mV in alkaline medium.

3D Hollow Quasi-Graphite Capsules/Polyaniline Hybrid with a High Performance for Room-Temperature Ammonia Gas Sensors.

Designing sensing materials with novel morphologies and compositions is eminently challenging to achieve high-performance gas sensor devices. Herein, an in situ oxidative polymerization approach is developed to construct three-dimensional (3D) hollow quasi-graphite capsules/polyaniline (GCs/PANI) hierarchical hybrids by decorating protonated PANI on the surface of GCs; as a result, an immensely active and sensitive material was developed for sensing ammonia gas at room temperature. Moreover, the GCs possessed a capsule-like hollow/open structure with partially graphitized walls, and PANI nanospheres were uniformly decorated on the GC surfaces.

Unveiling Property of Hydrolysis-Derived DMAPbI for Perovskite Devices: Composition Engineering, Defect Mitigation, and Stability Optimization.

Additive engineering has become increasingly important for making high-quality perovskite solar cells (PSCs), with a recent example involving acid during fabrication of cesium-based perovskites. Lately, it has been suggested that this process would introduce dimethylammonium ((CH)NH, DMA) through hydrolysis of the organic solvent. However, material composition of the hydrolyzed product and its effect on the device performance remain to be understood.

High-Temperature Oxidation-Resistant ZrNB/SiC Nanohybrid for Enhanced Microwave Absorption.

Most microwave absorbers lose their function under harsh working conditions, such as a high temperature and an oxidative environment. Here, we developed a heterogeneous ZrNB/SiC nanohybrid via combined catalytic chemical vapor deposition (CCVD) and chemical vapor infiltration (CVI) processes using ZrB as the starting material. The composition and structure of the ZrNB/SiC nanohybrid were controlled by tuning the CCVD and CVI parameters, such as reaction temperature, time, and reactant concentration.

Porous Eleocharis@MnPE Layered Hybrid for Synergistic Adsorption and Catalytic Biodegradation of Toxic Azo Dyes from Industrial Wastewater.

The effective treatment of industrial wastewater to protect freshwater reserves for the survival of life is a primary focus of current research. Herein, a multicomponent Eleocharis-manganese peroxidase enzyme (Eleocharis@MnPE) layered hybrid with high surface area (1200 m/m), with a strong synergistic adsorption and catalytic biodegradation (SACB), has been developed through a facile method. A combination of outer porous (Eleocharis) and inner catalytically active (MnPE) components of the hybrid resulted in highly efficient SACB system, evidenced by high removal rate of 15 kg m day (100%) and complete degradation of toxic Orange II (OR) azo dye into nontoxic products (gases and weak acids).

In Vivo and In Vitro Monitoring of Amyloid Aggregation via BSA@FGQDs Multimodal Probe.

Early detection of peptide aggregate intermediates is quite challenging because of their variable and complex nature as well as due to lack of reliable sensors for diagnosis. Herein, we report the detection of monomers and oligomers using specified fluorescence and a magnetic resonance imaging (MRI) multimodal probe based on bovine-serum-albumin-capped fluorine functionalized graphene quantum dots (BSA@FGQDs). This probe enables in vitro fluorescence-based monitoring of human islet amyloid polypeptide (hIAPP), insulin, and amyloid β (Aβ) monomers and oligomers during the fibrillogenesis dynamic.

NiFeO nanoparticles coated on 3D graphene capsule as electrode for advanced energy storage applications.

Current energy crises are inspiring researchers to focus intensively on development of feasible ways to produce high performing composite electrode materials for increasing energy demands. The present work addresses this objective by developing a novel structure of NiFe2O4 (NFO) nanoparticles coated on graphene capsules (GCs) by a simple hydrothermal technique. This NFO-GCs electrode material was subjected to different types of electrochemical performance evaluations to investigate its feasibility as a supercapacitor electrode.

A novel strategy to motivate the luminescence efficiency of a phosphor: drilling nanoholes on the surface.

A facile approach to fabricate nanoholes on the surface of a phosphor via a carbothermal reaction between C and BaMgAl10O17 was adopted. Drilling nanoholes greatly enhanced excitation light absorption and consequently increased the quantum efficiency, which provided new insight to help improve the luminescence efficiency of oxygen-containing phosphors.

Heterostructured Nanorings of Fe-FeO@C Hybrid with Enhanced Microwave Absorption Performance.

Microwave absorption is a critical challenge with progression in electronics, where fine structural designing of absorbent materials plays an effective role in optimizing their microwave absorption properties. Here, we have developed FeO@C (FC) and Fe-FeO@C (FFC) hybrid nanorings via a hydrothermal method coupled with a chemical catalytic vapor deposition technique. FC and FFC hybrid nanorings have fine carbon coating while their size can easily be tunable in a certain range from 80-130 to 90-140 nm.

Insight the Luminescence Properties of AlON: Eu, Mg Phosphor under VUV Excitation.

Owing to high quantum efficiency, adjustable composition and antioxidation properties of oxynitride phosphors, extensive investigations have focused on their photoluminescence properties under low-energy light excitation (UV or blue light). However, the vacuum ultraviolet (VUV) luminescence properties of oxynitride phosphors are rarely researched. Present work studies the structure and VUV luminescence properties of an oxynitride phosphor: AlON: Eu, Mg, which is synthesized by solid-state reaction.

Facile Synthesis of Three-Dimensional Sandwiched MnO@GCs@MnO Hybrid Nanostructured Electrode for Electrochemical Capacitors.

Designable control over the morphology and structure of active materials is highly desirable for achieving high-performance devices. Here, we develop a facile microwave-assisted synthesis to decorate MnO nanocrystals on three-dimensional (3D) graphite-like capsules (GCs) to obtain sandwich nanostructures (3D MnO@GCs@MnO) as electrode materials for electrochemical capacitors (ECs). A templated growth of the 3D GCs was carried out via catalytic chemical vapor deposition and MnO was decorated on the exterior and interior surfaces of the GC walls through microwave irradiation to build an engineered architecture with robust structural and morphological stability.

CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours.

G-quadruplex DNAs form four-stranded helical structures and are proposed to play key roles in different cellular processes. Targeting G-quadruplex DNAs for cancer treatment is a very promising prospect. Here, we show that CX-5461 is a G-quadruplex stabilizer, with specific toxicity against BRCA deficiencies in cancer cells and polyclonal patient-derived xenograft models, including tumours resistant to PARP inhibition.

Facile Synthesis of Fe3O4/GCs Composites and Their Enhanced Microwave Absorption Properties.

Graphene has good stability and adjustable dielectric properties along with tunable morphologies, and hence can be used to design novel and high-performance functional materials. Here, we have reported a facile synthesis method of nanoscale Fe3O4/graphene capsules (GCs) composites using the combination of catalytic chemical vapor deposition (CCVD) and hydrothermal process. The resulting composite has the advantage of unique morphology that offers better synergism among the Fe3O4 particles as well as particles and GCs.

High-purity Cu nanocrystal synthesis by a dynamic decomposition method.

Cu nanocrystals are applied extensively in several fields, particularly in the microelectron, sensor, and catalysis. The catalytic behavior of Cu nanocrystals depends mainly on the structure and particle size. In this work, formation of high-purity Cu nanocrystals is studied using a common chemical vapor deposition precursor of cupric tartrate.

Enhancement in photoluminescence performance of carbon-decorated T-ZnO.

The facile preparation of ZnO possessing high visible luminescence intensity remains challenging due to an unclear luminescence mechanism. Here, two basic approaches are proposed to enhance the luminescent intensity based on the theoretical analysis over surface defects. Based on the deduction, we introduce a methodology for obtaining hybrid tetrapod-like zinc oxide (T-ZnO), decorated by carbon nanomarterials on T-ZnO surfaces through the catalytic chemical vapor deposition approach.

Combined image and genomic analysis of high-grade serous ovarian cancer reveals PTEN loss as a common driver event and prognostic classifier.

Background: TP53 and BRCA1/2 mutations are the main drivers in high-grade serous ovarian carcinoma (HGSOC). We hypothesise that combining tissue phenotypes from image analysis of tumour sections with genomic profiles could reveal other significant driver events.

Results: Automatic estimates of stromal content combined with genomic analysis of TCGA HGSOC tumours show that stroma strongly biases estimates of PTEN expression.

Remarkable improvement in microwave absorption by cloaking a micro-scaled tetrapod hollow with helical carbon nanofibers.

Helical nanofibers are prepared through in situ growth on the surface of a tetrapod-shaped ZnO whisker (T-ZnO), by employing a precursor decomposition method then adding substrate. After heat treatment at 900 °C under argon, this new composite material, named helical nanofiber-T-ZnO, undergoes a significant change in morphology and structure. The T-ZnO transforms from a solid tetrapod ZnO to a micro-scaled tetrapod hollow carbon film by reduction of the organic fiber at 900 °C.

Controllable preparation of Ni nanoparticles for catalysis of coiled carbon fibers growth.

The mass preparation of high-purity coiled carbon fibers (CCFs) remains challenging due to the high complexity and low controllability of reaction. In this work, a controllable growth of Ni particles was fulfilled by liquid phase reduction of nickel sulfate with hydrazine hydrate. The impacts of the reaction temperature, NaOH concentration, and reaction time on the particle size and purity were investigated.