Synbiotic yacon juice fermented by Lactiplantibacillus plantarum QS7T attenuates dextran sodium sulfate-induced ulcerative colitis in mice.

Ulcerative colitis (UC) is a prevalent inflammatory bowel disease associated with abnormal immune responses to commensal bacteria. The study investigated the effects of synbiotic yacon juice fermented by Lactiplantibacillus plantarum QS7T (FYJ) on ameliorating UC and modulating gut microbiota in a dextran sodium sulfate (DSS)-induced colitis mouse model. FYJ intervention significantly improved body weight and colon length, reduced the disease activity index and histopathological scores, and effectively alleviated colon tissue damage compared with treatments with L.

Phenotypic and genomic characterization of Levilactobacillus brevis YT108: a potential probiotic strain capable of metabolizing xylo-oligosaccharides.

Levilactobacillus brevis YT108, identified for its ability to metabolize prebiotic xylo-oligosaccharides (XOS), emerges as a candidate for probiotic use in synbiotic food formulations. This study aimed to investigate the metabolic and genomic traits associated with XOS metabolism in YT108 and to assess its probiotic attributes through whole genome sequencing and in vitro assays. Strain YT108 exhibited robust growth kinetics on XOS as the sole carbon source, with a growth profile comparable to that on glucose, achieving a pH reduction to 4.

Comparative transcriptomic analysis reveals a potential link between sugar transporters and the diauxic growth of Weissella paramesenteroides YT175 on inulin.

Inulin, a health-promoting dietary fiber, is efficiently metabolized by Weissella paramesenteroides YT175, a beneficial bacterium. The strain demonstrated a diauxic growth pattern within 48 h, reaching an optical density at 600 nm (OD) of approximately 1.5, accompanied by a significant decrease in pH to around 4.

Value of Myocardial Strain in Monitoring Fluorouracil-Based Chemotherapy-Related Cardiac Dysfunction in Gastrointestinal Cancer Patients.

Objectives: To investigate the predictive value of myocardial strain for cardiotoxicity associated with fluorouracil-based chemotherapies in gastrointestinal cancer patients.

Methods: Patients with diagnosis of gastrointestinal cancers, who were hospitalized for chemotherapy involving antimetabolic drugs, were eligible in this prospective study. Echocardiography was performed before and after each chemotherapy cycle during hospitalization until the completion of chemotherapy.

Phenotypic and genomic analysis of inulin consumption by Lactiplantibacillus plantarum strains from Sichuan pickle.

Aims: To investigate the capability, properties, and molecular mechanism of inulin fermentation by lactic acid bacteria (LAB) from Sichuan pickle.

Methods And Results: A total of 79 LAB strains were purified from 30 aged Sichuan pickle brine samples, and only 21 Lactiplantibacillus plantarum strains (26.58%, 21/79) derived from 15 samples grew well through utilizing inulin as a carbon source.

Global genome and comparative transcriptomic analysis reveal the inulin consumption strategy of Lactiplantibacillus plantarum QS7T.

Sichuan pickle is a natural combination of probiotics and dietary fibers, in which a strain Lactiplantibacillus plantarum QS7T was found to be capable of efficiently metabolizing inulin. However, the underlying molecular mechanism of inulin consumption by the strain QS7T is unclear. Therefore, this study firstly investigated the metabolic characteristics of inulin in the strain QS7T, and the results showed it could grow very well on the medium containing inulin as a carbon source (maximum OD, 1.

Warming delays the phenological sequences of an autumn-flowering invader.

Phenology can play an important role in driving plant invasions; however, little is known about how climate warming, nitrogen (N) deposition, and invasion stages influence the phenological sequences of autumn-flowering invaders in a subtropical climate. Accordingly, we conducted an experiment to address the effects of experimental warming, N-addition, and community types on the first inflorescence buds, flowering, seed-setting, and dieback of invasive . Warming delayed the onset of first inflorescence buds, flowering, seed-setting, and dieback; N-addition did not influence these four phenophases; community types influenced the onset of first seed-setting but not the other phenological phases.

Dissecting -soil feedback in its real invasion.

The importance of plant-soil feedback (PSF) has long been recognized, but the current knowledge on PSF patterns and the related mechanisms mainly stems from laboratory experiments. We aimed at addressing PSF effects on community performance and their determinants using an invasive forb . To do so, we surveyed 81 pairs of invaded versus uninvaded plots, collected soil samples from these pairwise plots, and performed an experiment with microcosm plant communities.

Altered neurotransmitter levels with post-traumatic stress disorder.

Aim: The aim of this study was to observe the changes in the monoamine neurotransmitter levels of patients with post-traumatic stress disorder (PTSD) and explore whether the neurotransmitter level is correlated with the severity of PTSD.

Material And Methods: A total of 15 PTSD patients without any physical injuries were enrolled into the study. Another 15 cases of pre-restoration patients were recruited as controls who experienced traumatic events but did not experience PTSD or had a Posttraumatic stress disorder Check List-Civilian version (PCL-C) score lower than 12 points.