Chaperone-mediated autophagy protects the bone formation from excessive inflammation through PI3K/AKT/GSK3β/β-catenin pathway.

Multiple regulatory mechanisms are in place to ensure the normal processes of bone metabolism, encompassing both bone formation and absorption. This study has identified chaperone-mediated autophagy (CMA) as a critical regulator that safeguards bone formation from the detrimental effects of excessive inflammation. By silencing LAMP2A or HSCA8, we observed a hindrance in the osteoblast differentiation of human bone marrow mesenchymal stem cells (hBMSCs) in vitro.

"UV-Driven Self-Cleaning" Magnetic Molecularly Imprinted Absorbents Coupled with LTP-MS and LC-TQ-MS for Rapid High-Throughput Screening and Quantification of Organophosphorus Pesticides in Agro-products.

Organophosphorus magnetic molecularly imprinted polymers (OMMIPs) with high adsorption capacities (13.5-83.8 mg g) and good applicability were developed for efficient extraction and pre-concentration of multiple organophosphorus pesticides (OPPs) from foodstuffs.

Sex-specific differences in ossification patterns of the atlas and axis: a computed tomography study.

Background: We investigated the sex-specific differences in ossification patterns of the first two cervical vertebrae in Chinese children.

Methods: A retrospective computed tomography (CT) study was performed between June 2016 and December 2020. Patients younger than 16 years with cervical CT images acquired ≤ 1.

The role of skin and subcutaneous tissues in Dupuytren's contracture: an electron microscopic observation.

Objective: To determine the relationship between the overlying tissues and recurrence of Dupuytren's contracture.

Methods: Forty-three patients (68 hands) who accepted surgical treatment were divided into two groups according to treatment methods: partial fasciectomy or dermofasciectomy and full-thickness skin graft. Diseased palmar fascia, subcutaneous tissues and skin obtained during surgery were then assessed by electron microscopy.

Biomechanical research on anterior double-plate fixation for vertically unstable sacroiliac dislocations.

Objective: To determine the best method for anterior internal fixation by comparing the biomechanical characteristics of various anterior fixation methods for vertically unstable sacroiliac dislocations.

Methods: Eight pelves with Tile C fracture with vertical loading were measured separately. Three- and two-hole anterior double plates were fixed at different angles and compared with sacroiliac screws.

Performance of Anammox granular sludge bed reactor started up with nitrifying granular sludge.

The anaerobic ammonia oxidation (Anammox) granular sludge bed reactor was started up successfully with nitrifying granular sludge. During the operation, the nitrifying granular sludge was gradually converted into Anammox granular sludge with good settling property and high conversion activity. The Anammox reactor worked well with the shortest HRT of 2.

Start-up of anaerobic ammonia oxidation bioreactor with nitrifying activated sludge.

The anaerobic ammonia oxidation(Anammox) bioreactor was successfully started up with the nitrifying activated sludge. After anaerobically operated for 105 d, the bioreactor reached a good performance with removal percentage of both ammonia and nitrite higher than 95% and volumetric total nitrogen removal as high as 149.55 mmol/( L.

[Performance of internal-loop air-lift nitrifying bioreactor].

The performance of internal-loop air-lift nitrifying bioreactor was good with strong tolerance to influent ammonia concentration (78.49 mmol/L), high volume converting rate (163.18 mmol/L.