Biphasic regulation by bile acids of dermal fibroblast proliferation through regulation of cAMP production and COX-2 expression level.

We have previously reported that the bile acids chenodeoxycholate (CDCA) and ursodeoxycholate (UDCA) decreased PGE1-induced cAMP production in a time- and dose-dependent manner not only in hepatocytes but also in nonhepatic cells, including dermal fibroblasts. In the present study, we investigated the physiological relevance of this cAMP modulatory action of bile acids. PGE1 induced cAMP production in a time- and dose-dependent manner.

[Investigation of multi-channel collecting and temperature calculating by using minimum error principle for thermal radiation spectra].

A new kind of method of multi-channel acquisition of thermal radiation spectra and temperature calculating was reported in this paper. Employing a tungsten lamp as thermal source, using an optical multi-channel analyzer(OMA) to collect the radiation spectra, the measured temperatures were calculated by using optimum simulation between the measured spectra and Planck black body radiation curves at the determine temperatures according to the minimum errors principle. The results are agreement with standard values, and the errors are near 1%.