Molecular enhancement of Cu-based catalysts for CO electroreduction.

The electrochemical carbon dioxide reduction reaction (eCORR) represents an effective means of achieving renewable energy storage and a supply of carbon-based raw materials. However, there are still great challenges in selectively producing specific hydrocarbon compounds. The unique ability of the copper (Cu) catalyst to promote proton-coupled electron transfer processes offers clear advantages in generating value-added products.

One Iron for Two Iron Sites in a Metal-Organic Framework Toward Simultaneous N-H Activation under Mild Conditions.

Iron-based catalysts play an important role in the ammonia industry. As one of the most abundant iron minerals, FeO containing Fe and Fe sites is widely distributed in the earth's crust and even on exoplanets, theoretically giving it both economic and catalytic potentials in ammonia synthesis. However, in the absence of specific active co-catalyst and harsh conditions, FeO is impossible to achieve ammonia synthesis alone.

Bottom-Up Construction of Rhombic Lamellar CoNi-MOFs for the Electrochemical Sensing of HS.

Lamellar metal-organic frameworks (MOFs) have attracted significant attention in the field of electrochemical sensing due to their abundant open active sites and specific electron conductivity. Herein, by employing a bottom-up synthesis strategy, rhombic lamellar heterometallic CoNi-MOFs with varying thicknesses are constructed. This is achieved by using 4-methylpyridine as a capping agent based on the (4,6)-linked Co(azpy)(bptc) (azpy = 4,4'-azopyridine, bptc = 3,3',5,5'-biphenyltetracarboxylic acid) structure with a topology and by introducing Ni species simultaneously.

3-O-Methyl-D-Glucose Blunts Cold Ischemia Damage in Kidney via Inhibiting Ferroptosis.

Background: The glucose derivative 3-O-methyl-D-glucose (OMG) is used as a cryoprotectant in freezing cells. However, its protective role and the related mechanism in static cold storage (CS) of organs are unknown. The present study aimed to investigate the effect of OMG on cod ischemia damage in cold preservation of donor kidney.

Hierarchical surface-modification of nano-Cu toward one pot H-transfer-coupling-cyclization-CO fixation tandem reactions.

Fixation of CO into dihydroisobenzofuran derivatives has enormous applications in both production of natural products and antidepressant drugs, and reducing the green-house effect. However, the relatively complicated multi-step processes limit the further expansion of such a valuable CO conversion strategy. Herein, we hierarchically modify the surface of Cu nanoparticles (NPs) with Ag NPs and the robust metal-organic framework (MOF), ZIF-8, and report the presence of the Cu-Ag yolk-shell nanoalloy based heterogeneous catalysts, Cu@Ag and Cu@Ag@ZIF-8.

Crystal Engineering of a Chiral Crystalline Sponge That Enables Absolute Structure Determination and Enantiomeric Separation.

Chiral metal-organic materials (CMOMs), can offer molecular binding sites that mimic the enantioselectivity exhibited by biomolecules and are amenable to systematic fine-tuning of structure and properties. Herein, we report that the reaction of Ni(NO), -indoline-2-carboxylic acid (-IDECH), and 4,4'-bipyridine (bipy) afforded a homochiral cationic diamondoid, , network, [Ni(-IDEC)(bipy)(HO)][NO], . Composed of rod building blocks (RBBs) cross-linked by bipy linkers, the activated form of adapted its pore structure to bind four guest molecules, 1-phenyl-1-butanol (1P1B), 4-phenyl-2-butanol (4P2B), 1-(4-methoxyphenyl)ethanol (MPE), and methyl mandelate (MM), making it an example of a chiral crystalline sponge (CCS).

Ultrastable Cu-Based Dual-Channel Heterowire for the Switchable Electro-/Photocatalytic Reduction of CO.

Catalytic conversion of CO into high value-added chemicals using renewable energy is an attractive strategy for the management of CO . However, achieving both efficiency and product selectivity remains a great challenge. Herein, a brand-new family of 1D dual-channel heterowires, Cu NWs@MOFs are constructed by coating metal-organic frameworks (MOFs) on Cu nanowires (Cu NWs) for electro-/photocatalytic CO reductions, where Cu NWs act as an electron channel to directionally transmit electrons, and the MOF cover acts as a molecule/photon channel to control the products and/or undertake photoelectric conversion.

Tailored Sky-Parking Architectures of 3D Graphene Oxide Towards Highly-Efficient Water Purification.

The widespread use of chemicals has brought serious water pollution threatening human health and environment, which requires green, fast, and low-cost purification urgently. Here, we build up a novel material family of sky-parking-like 3D structured graphene oxides (SP-GOs) with adjustable interlayer-space of 0.8-1.

Highly Robust Microporous Metal-Organic Frameworks for Efficient Ethylene Purification under Dry and Humid Conditions.

Two C H -selective metal-organic framework (MOF) adsorbents with ultrahigh stability, high surface areas, and suitable pore size have been designed and synthesized for one-step separation of ethane/ethylene (C H /C H ) under humid conditions to produce polymer-grade pure C H . Experimental results reveal that these two MOFs not only adsorb a high amount of C H but also display good C H /C H selectivity verified by fixed bed column breakthrough experiments. Most importantly, the good water stability and hydrophobic pore environments make these two MOFs capable of efficiently separating C H /C H under humid conditions, exhibiting the benchmark performance among all reported adsorbents for separation of C H /C H under humid conditions.

Pseudocapsule and pseudocapsule-based extracapsular resection in pituitary neuroendocrine tumors.

Since Costello et al. proposed the concept of pseudocapsule of pituitary neuroendocrine tumors (PitNETs) in 1936, many studies have been published on its occurrence, development process, histopathology, and morphology. Pseudocapsule has been proposed as the anatomical interface between PitNETs and normal pituitary gland, therefore the so-called pseudocapsule-based extracapsular resection (ER) technique was developed as an extracapsular surgery method for PitNETs,which differs from the conventional intracapsular resection (IR).

Protocol to modify the surface of nano-CuO using facet controlling and MOF shell coating.

The morphology of nano-CuO profoundly determines its catalytic performance. Here, we provide two universal and reliable techniques to modify the surface of nano-CuO. First, we detail steps for the systematic tuning of the exposed facets of nano-CuO ranging from low index to high index using reductant-controlled technique in the presence of sodium dodecyl sulfate.

MOF-Incorporated Binuclear N-Heterocyclic Carbene-Cobalt Catalyst for Efficient Conversion of CO to Formamides.

Environmental problem caused by carbon emission is of widespread concern. Involving CO as C resource into chemical synthesis is one of the most attractive ways for carbon recycling. Herein, the first example of host-guest composites featuring metal-organic framework (MOF)-encapsulated binuclear N-heterocyclic carbene (NHC) complex, Co @MIL101, was developed with the molecularly dispersed [Co(IPr)Br] (μ-Br) (Co ) loading in the cage of MIL-101(Cr) via a "ligand-in-dimer-trap" strategy, which was comprehensively investigated through various techniques including synchrotron X-ray absorption, electron microscopy, X-ray diffraction, solid-state nuclear magnetic resonance spectroscopy, and others.

Hybrid Metal-Organic Frameworks Encapsulated Hybrid Ni-Doped CdS Nanoparticles for Visible-Light-Driven CO Reduction.

The photocatalytic production of syngas from CO and water is an attractive and straightforward way for both solar energy storage and sustainable development. Here, we combined the hybrid shell of a bimetallic metal-organic framework (MOF) Zn/Co-zeolitic imidazolate framework (ZIF) and the hybrid photoactive center of Ni-doped CdS nanoparticles (Ni@CdS) to construct a new "2 + 2" photocatalysis system Ni@CdS⊂Zn/Co-ZIF through a facile self-assembly process, which exhibited a double-synergic effect for visible light harvesting and CO conversion, leading to one of the highest photocatalytic syngas production rates and excellent recyclability. The H/CO of syngas ratios can be readily adjusted by controlling the ratio of Zn/Co in the hybrid MOF shell.

Effects of prolonged cold ischemia on the DCD kidney function and Inflammasome expression in rat kidney transplants.

Background: Acute kidney injury (AKI) is the main reason for the bad outcome of the donation of circulatory death (DCD) kidney after transplantation. Prolonged cold storage (CS) is a risk factor for the occurrence of the delayed graft function in DCD kidney. The protein NLR-domain containing receptor 3 (NLRP3) plays a crucial role in renal ischemia reperfusion injury by triggering inflammasome formation.

Surface Modification of Nano-Cu O for Controlling CO Electrochemical Reduction to Ethylene and Syngas.

In the surroundings of carbon neutrality, nano-Cu O is considered a promising catalyst for the electrochemical CO reduction reaction (ECO RR), whose improvements in product selectivity still require considerable efforts. Here, we present an efficient strategy for controlling the ECO RR product by modifying the surface of nano-Cu O, i.e.

Construction of Cu Defects on CuCl Nanoparticles in Metal-Organic Frameworks toward Composite Catalysts with Superior Activity.

Metal-organic frameworks (MOFs) represent an ideal platform for the construction of highly active composite catalysts. However, loading metastable and/or multicomponent metal compounds into MOFs remains a synthetic bottleneck due to the great challenge of keeping the guest and matrix intact during the preparation of a composite. In this work, we develop a new impregnation reduction surface modification (IRSM) strategy to give a new composite catalyst CuCl@MIL-101(Cr), which is successfully postmodified by construction of Cu defects on the surface of loaded CuCl inside MOF pores, leading to the new composite material Cu/Cu@MIL-101(Cr).

Fabrication of Moisture-Responsive Crystalline Smart Materials for Water Harvesting and Electricity Transduction.

It is of profound significance with regard to the global energy crisis to develop new techniques and materials that can convert the chemical potential of water into other forms of energy, especially electricity. To address this challenge, we built a new type of energy transduction pathway (humidity gradients → mechanical work → electrical power) using moisture-responsive crystalline materials as the media for energy transduction. Single-crystal data revealed that a flexible zeolitic pyrimidine framework material, , could undergo a reversible structural transformation (β to α phase) with a large unit cell change upon moisture stimulus.

Controlled Thermal Conversion Strategy to Provide Metal-Organic Framework-Supported Composite Catalysts.

Metal-organic framework (MOF)-supported metal/metal compound nanoparticles (NPs) have emerged as a new class of composite catalysts. However, huge challenges prevail in placing such NPs in the MOF pores because of the poor solubility of metal/metal oxides, limited availability of suitable precursors, metastable attribute of given metal ions, and lower thermal stability of MOFs compared to conventional porous materials. Based on the difference between the thermal stability of the precursor and MOFs, we successfully developed a controlled thermal conversion (CTC) method to load cobalt(II) oxide (CoO) NPs into the framework of MOF (MIL-101) to conveniently obtain a composite catalyst, CoO@MIL-101, which is a very rare example of pure CoO NP-loaded composite catalyst that shows excellent catalytic activity in the selective oxidation of benzyl alcohol.

Conversion of CO to Heterocyclohexenol Carboxylic Acids through a Metal-Organic Framework Sponge.

The conversion of CO into high value-added chemical products is the focus of current scientific research. We make use of the specific porous structure of nanosized metal-organic frameworks (MOFs) loading the highly active yet metastable nano CuO to catalyze the conversion of CO into a series of high value-added bioactive pyridone/pyrone-3-carboxylic acid products via heterocyclic 4-hydroxy-2-pyridones/pyrones, which exhibit high activity, selectivity, and reusability. Nano MOF sponge-covered metastable nanoparticles (NPs) converting CO into high value-added bioproducts provide a facile "dual-side surfactant" strategy, a highly efficient composite catalyst, and a practicable pathway not only for the sustainable use of CO but also for environment-friendly production of bioproducts.

Application of MOF-based materials in electrochemical sensing.

Metal-organic frameworks (MOFs) have risen as a kind of porous materials that are constructed by the coordination of organic ligands to metal centers or clusters, providing compelling potential for various fields of research. In this frontier article, we demonstrate the recent developments in MOF-based materials for electrochemical sensing applications, and the current challenges and some prospects in this field are also discussed.

Toward Green Production of Chewing Gum and Diet: Complete Hydrogenation of Xylose to Xylitol over Ruthenium Composite Catalysts under Mild Conditions.

Xylitol is one of the most famous chemicals known to people as the essential ingredient of chewing gum and as the sugar alternative for diabetics. Catalytic hydrogenation of biomass-derived xylose with H to produce high-value xylitol has been carried out under harsh reaction conditions. Herein, we exhibit the combination of Ru NPs with an environmentally benign MOF (ZIF-67) to afford a heterogeneous composite catalyst.

A systematic investigation of structural transformation in a copper pyrazolato system: a case study.

Dissolution-recrystallization structural transformation (DRST) is a powerful tool to unravel unequivocally the mechanism of dynamic conversion processes, based on the structures of the initial reactants, final products and sometimes intermediates isolated from the reaction mixture. Herein, we illustrate the details of the conversion processes of (CuIpz)3 into [CuII(OH)pz]6 (pzH = 4-chloro-3,5-diphenylpyrazole) through DRSTs. Based on crystal structure determination and spectroscopic methods, the most encountered species, (CuIpz)3, is in equilibrium with (CuIpz)4 in solution with the tetramer becoming dominant at low temperature, indicating an entropy-controlled conversion between these two structural isomers.

Basilar Artery Tortuosity Is Associated With White Matter Hyperintensities by TIMP-1.

Background And Purpose: To test the hypothesis that the imbalance between matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs) may play a potential role in bridging vertebrobasilar dolichoectasia (VBD) with lacunar infarction (LI) and white matter hyperintensities (WMH).

Methods: We studied 212 patients with vertigo who underwent multimodal magnetic resonance imaging (MRI) tests for VBD, LI, and WMH identification. We investigated biomarkers of VBD with magnetic resonance angiography (MRA) via various physical characteristics of the vertebrobasilar arteries (VBAs).

Solvent-assisted coordination driven assembly of a supramolecular architecture featuring two types of connectivity from discrete nanocages.

The rapid development of supramolecular chemistry provides a powerful bottom-up approach to construct various well-defined nano-architectures with increasing complexity and functionality. Compared to that of small and simple nanometric objects, the self-assembly of larger and more complex nanometric objects, such as nanocages, remains a significant challenge. Herein, we used a discrete nanocage as the monomer to successfully construct a novel three-dimensional (3D) supramolecular architecture, which comprises two types of nanocage building units with different connectivity, using the solvent-assisted coordination-driven assembly approach.