Rapid configuring method for a programmable photonic integrated circuit based on a tandem neural network.

Programmable photonic integrated circuits (PPICs), as optical analog matrix multipliers, emerge as a leading candidate of a revolutionary technology. However, the efficient voltage configuration of programmable devices in the circuit presents a significant challenge to its development. Here, we propose a black-box method based on tandem neural network to rapidly predict the voltage configuration of arbitrary matrices.

Highly Selective Electrocatalytic 1,4-NADH Regeneration Based on Host-Guest Recognition Mediated by Cucurbit[8]uril on NiO.

Efficient regeneration of nicotinamide adenine dinucleotide (NADH) cofactors, particularly 1,4-NADH, is crucial for advancing oxidoreductase catalysis. Electrocatalysis provides a promising route for 1,4-NADH regeneration, but an expensive catalyst, typically a rhodium organometallic complex, is frequently required to guarantee the high selectivity of 1,4-NADH, significantly limiting its large-scale application. Herein, inspired by the catalytic pocket and enzyme-substrate interaction in nature, a direct electrochemical 1,4-NADH regeneration route was designed by modification of the surface of nickel oxide (NiO) with cucurbit[8]uril (CB[8]) (denoted as CB[8]-NiO).

Global research landscape and hotspots for ferroptosis in glioma: A comprehensive bibliometric and visual analysis.

Studying ferroptosis is crucial for understanding the mechanisms underlying the onset and progression of glioblastoma, identifying therapeutic targets, and improving prognosis assessment and diagnostic methods. While recent research has explored the link between ferroptosis and glioblastoma, there is a lack of comprehensive bibliometric analyses specifically addressing this relationship and its connection to glioblastoma. To address this gap, we conducted a thorough analysis of 225 relevant articles on glioma and ferroptosis obtained from the Web of Science database covering the period from 2012 to 2023, employing rigorous exclusion criteria.

Superior energy storage capacity of polymer-based bilayer composites by introducing 2D ferroelectric micro-sheets.

Dielectric polymer capacitors suffer from low discharged energy density and efficiency due to their low breakdown strength, small dielectric constant and large electric hysteresis. Herein, a synergistic enhancement strategy is proposed to significantly increase both breakdown strength and dielectric constant while suppressing hysteresis, through introducing 2-dimensional bismuth layer-structured NaBiTiO micro-sheets and designing a unique bilayer structure. Excitingly, an ultra-high discharged energy density of 25.

METTL3: a multifunctional regulator in diseases.

N6-methyladenosine (mA) methylation is the most prevalent and abundant internal modification of mRNAs and is catalyzed by the methyltransferase complex. Methyltransferase-like 3 (METTL3), the best-known mA methyltransferase, has been confirmed to function as a multifunctional regulator in the reversible epitranscriptome modulation of mA modification according to follow-up studies. Accumulating evidence in recent years has shown that METTL3 can regulate a variety of functional genes, that aberrant expression of METTL3 is usually associated with many pathological conditions, and that its expression regulatory mechanism is related mainly to its methyltransferase activity or mRNA posttranslational modification.

Efficacy and durability of cobalt sulfide nanoparticles and axial sulfur-coordinated cobalt single-atom composite sites in hydrogenative nitroaromatics decontamination.

Emerging single-atom materials and metal sulfides hold significant promise as alternatives to precious metal catalysts for nitroaromatics conversion; however, their intrinsic activity and durability remain insufficiently understood. Herein, sulfur and nitrogen co-doped carbon matrices incorporating CoS nanoparticles and single-atom Co with Co-N-S coordination were constructed through a facile pyrolysis approach. Advanced characterization techniques, such as X-ray absorption fine structure (XAFS) and aberration-corrected electron microscopy, unveiled unique structural features underpinning exceptional catalytic efficiency and recyclability.

Iron-Quercetin complex enhances mesenchymal stem cell-mediated HGF secretion and c-Met activation to ameliorate acute kidney injury through the prevention of tubular cell apoptosis.

Background: Acute kidney injury (AKI) is a life-threatening clinical syndrome with no effective treatment currently available. This study aims to investigate whether Iron-Quercetin complex (IronQ) pretreatment can enhance the therapeutic efficacy of Mesenchymal stem cells (MSCs) in AKI and explore the underlying mechanisms.

Methods: A cisplatin-induced AKI model was established in male C57BL/6 mice, followed by the intravenous administration of 1x10ˆ6 MSCs or IronQ-pretreated MSCs (MSC).

Novel perspective on particulate matter and Alzheimer's disease: Insights from adverse outcome pathway framework.

Alzheimer's disease (AD) is a neurodegenerative disease, that accounts for 50-75% of all dementia cases. Evidence demonstrates the link between particulate matter (PM) exposure and AD. However, there are still considerable research gaps.

Fluidic Oscillation-Based Pneumatic Actuation for Soft Locomotion and Grasping.

Most pneumatic actuators used in robotics are controlled by valves that contain moving parts (e.g., spool or rotor) and electronics to change the direction or pressure of the air flow.

3D Printed Multi-Cavity Soft Actuator with Integrated Motion and Sensing Functionalities via Bio-Inspired Interweaving Foldable Endomysium.

The human muscle bundle generates versatile movements with synchronous neurosensory, enabling human to undertake complex tasks, which inspires researches into functional integration of motions and sensing in actuators for robots. Although soft actuators have developed diverse motion capabilities utilizing the inherent compliance, the simultaneous-sensing approaches typically involve adding sensing components or embedding certain-signal-field substrates, resulting in structural complexity and discrepant deformations between the actuation parts with high-dimensional motions and the sensing parts with heterogeneous stiffnesses. Inspired by the muscle-bundle multifiber mechanism, a multicavity functional integration (McFI) approach is proposed for soft pneumatic actuators to simultaneously realize multidimensional motions and sensing by separating and coordinating active and passive cavities.

Exploring the application status of qualitative studies in the research area of acupuncture: a scoping review protocol.

Introduction: With the wide development of acupuncture clinical practice, acupuncture research has been conducted worldwide, of which the most common method is quantitative study. However, research questions around acupuncture cannot always be addressed by quantitative studies due to their intrinsic characteristics. Qualitative studies can perfectly complement this knowledge gap in acupuncture research.

A Case Report on the Short-Term Recurrence of Low-Grade Fibromyxoid Sarcoma in the Maxillary Sinus.

Low-grade fibromyxoid sarcoma (LGFMS) represents an exceptionally rare soft-tissue tumor, challenging to diagnose, and notorious for relentless recurrence and proliferation postsurgical resection. Primary symptoms of LGFMS include nasal congestion and rhinorrhea, accompanied by cheek numbness and distension. In this article, we report the diagnosis and treatment of a case of low-grade LGFMS originating in the maxillary sinus (MS).

Astragaloside IV ameliorates pressure overload-induced heart failure by enhancing angiogenesis through HSF1/VEGF pathway.

Astragaloside IV(AS-IV), the main active ingredient of Astragalus, has been used as a treatment for heart failure with favorable effects, but its molecular mechanism has not been fully elucidated. Network pharmacological analysis and molecular docking revealed that Heat shock transcription factor 1 (HSF1) is a potential target of AS-IV. We designed cellular and animal experiments to investigate the role and intrinsic molecular mechanisms of AS-IV in ameliorating pressure overload-induced heart failure.

Establishment of a predictive model for blood transfusion after femoral head replacement in elderly patients.

Objectives: The study aimed to establish a nomogram predictive model for blood transfusion after artificial femoral head replacement surgery in elderly patients with intertrochanteric fractures.

Patients And Methods: Two hundred five elderly patients (55 males, 150 females; mean age: 82.1±6.

The complete chloroplast genome of (gentianaceae) and its phylogenetic analysis.

To elucidate the genetic information and evolutionary relationships of , we initiated the sequencing of the complete chloroplast genome of Franch. 1888, complemented by comparative analyses with closely related species. The chloroplast genome of was 153,516 bp in length and exhibited a typical quadripartite structure.

Modulating Elasticity of Liposome for Enhanced Cancer Immunotherapy.

Cancer immunotherapy has emerged as a promising approach to cancer treatment in recent years. The physical and chemical properties of nanocarriers are critical factors that regulate the immune activation of antigen-presenting cells (APCs) in the tumor microenvironment (TME). Herein, we extensively investigated the behavior of liposome nanoparticles (Lipo-NPs) with different elasticities, focusing on their interaction with immune cells and their transport mechanisms from tumors to tumor-draining lymph nodes (tdLNs).

Nutrition-Related Knowledge Graph Neural Network for Food Recommendation.

Food recommendation systems are becoming increasingly vital in modern society, given the fast-paced lifestyle and diverse dietary habits. Existing research and implemented solutions often rely on user preferences and past behaviors for recommendations, which poses significant issues. Firstly, this approach inadequately considers the nutritional content of foods, potentially leading to recommendations that are overly homogeneous and lacking in diversity.

Effect of Luhong formula on the cardiac rehabilitation of patients with chronic heart failure.

Background: Current treatments for chronic heart failure (CHF) are therapeutically ineffective. The optimization of treatments for this disease needs to be explored and analyzed.

Aim: To analyze the effect of using Luhong Formula in the cardiac rehabilitation of patients with CHF and its influence on cardiopulmonary function (CPF) and prognosis.

Explosion of research on psychopathology and social media use after COVID-19: A scientometric study.

Background: Despite advances in research on psychopathology and social media use, no comprehensive review has examined published papers on this type of research and considered how it was affected by the coronavirus disease 2019 (COVID-19) outbreak.

Aim: To explore the status of research on psychopathology and social media use before and after the COVID-19 outbreak.

Methods: We used Bibliometrix (an R software package) to conduct a scientometric analysis of 4588 relevant studies drawn from the Web of Science Core Collection, PubMed, and Scopus databases.

The development and evolution of the research topic on the mental health of college students: A bibliometric review based on CiteSpace and VOSviewer.

Background: With the advances in society and in response to changing times, college students have had to face multiple challenges. These challenges frequently affect the mental health of college students, leading to significant consequences for their social lives, personal well-being, and academic achievements, thereby attracting extensive societal attention. Therefore, examining the current status of research topics related to the mental health of college students can assist academia in dissecting the influencing factors and seeking solutions at their source or through early intervention.

Lactic acid bacteria modulate the CncC pathway to enhance resistance to β-cypermethrin in the oriental fruit fly.

The gut microbiota of insects has been shown to regulate host detoxification enzymes. However, the potential regulatory mechanisms involved remain unknown. Here, we report that gut bacteria increase insecticide resistance by activating the cap "n" collar isoform-C (CncC) pathway through enzymatically generated reactive oxygen species (ROS) in Bactrocera dorsalis.

Enhancing Soybean and Maize Yields through Improved Nitrogen and Soil Water Use Efficiencies: A 40-Year Study on the Impact of Farmyard Manure Amendment in Northeast China.

The combined application of manure and chemical fertilizers has been recognized as a critical factor driving significant changes in crop yield and nutrient use efficiency, holding the potential to optimize agricultural management to achieve high yields. In this 40-year study, we investigated the effect of manure amendment on soybean and maize yields, water and nitrogen use efficiencies (WUE and NUE), and water and mineral N storage at 0-100 cm soil depths from 2017 to 2018 to explore the optimization of fertilization management strategies for soybean and maize production in Northeast China. To elucidate the impact of chemical fertilizers and manure, twelve treatments-control (CK); single N fertilizer at a low rate (N) and that at a high rate (N); N, phosphorus (P), and potassium (K) fertilizer (NPK); manure alone at 13.