Pitch angle and altitude control for unmanned helicopter based on new approximation-free control.

This article introduces an enhanced non-approximated control technique for the pitch and altitude control systems of unmanned helicopters. It takes into account unpredictable external disturbances and system dynamics. The integration of prescribed performance control into unmanned helicopter systems significantly improves the transient and steady-state response capabilities.

Hypothalamic transcriptome profile from laying period to incubation period of Changshun green-shell laying hens.

Incubation behavior in chickens is closely associated with hypothalamus. Here, RNA sequencing of hypothalamus from Changshun green-shell laying hens, an indigenous chicken breed from China, in egg-laying period (LP) and incubation period (BP) was conducted to identify critical pathways and candidate genes involved in controlling the incubation behavior in hypothalamus. A total of 637 up-regulated and 305 down-regulated differently expressed genes (DEGs) were identified in chicken hypothalamus between LP and BP groups.

Improved moth-flame algorithm based on cat chaotic and dynamic cosine factor.

The moth-flame algorithm shows some shortcomings in solving the complex problem of optimization, such as insufficient population diversity and unbalanced search ability. In this paper, an IMFO (Improved Moth-Flame Optimization) algorithm is proposed to be applied in solving the optimization problem of function. First, cat chaotic mapping is used to generate the initial position of moth to improve the population diversity.

A Comparative Assessment of Different Aerogel-Insulated Building Walls for Enhanced Thermal Insulation Performance.

Aerogel is widely recognized as a superinsulating material with great potential for enhancing the thermal insulation performance of building walls. It can be applied in various forms such as aerogel plasters (AP), aerogel fibrous composites (AFC), and aerogel concrete (AC) in practical engineering applications. This study aims to investigate the most efficient application form for maximizing building insulation performance while minimizing the amount of aerogel used.

[Development of Vital Signal Monitoring System Based on Accelerometer].

Objective: Reduce the number of false alarms and measurement time caused by movement interference by the sync waveform of the movement.

Methods: Vital signal monitoring system based on motion sensor was developed, which collected and processed the vital signals continuously, optimized the features and results of vital signals and transmitted the vital signal results and alarms to the interface.

Results: The system was tested in many departments, such as digestive department, cardiology department, internal medicine department, hepatobiliary surgery department and emergency department, and the total collection time was 1 940 h.

A fault diagnosis method for building electrical systems based on the combination of variational modal decomposition and new mutual dimensionless.

The fault diagnosis of building electrical systems are of great significance to the safe and stable operation of modern intelligent buildings. In this paper, it has many problems, such as various fault types, inconspicuous fault characteristics, uncertainty of fault type and mode, irregularity, unstable signal, large gap between fault data classes, small gap between classes and nonlinearity, etc. A method of building electrical system fault diagnosis based on the combination of variational mode decomposition and mutual dimensionless indictor (VMD-MDI) and quantum genetic algorithm-support vector machine (QGA-SVM) is proposed.

Construction of Polypyrrole-Coated CoSe Composite Material for Lithium-Sulfur Battery.

Lithium-sulfur batteries with high theoretical energy density and cheap cost can meet people's need for efficient energy storage, and have become a focus of the research on lithium-ion batteries. However, owing to their poor conductivity and "shuttle effect", lithium-sulfur batteries are difficult to commercialize. In order to solve this problem, herein a polyhedral hollow structure of cobalt selenide (CoSe) was synthesized by a simple one-step carbonization and selenization method using metal-organic bone MOFs (ZIF-67) as template and precursor.

Fault Diagnosis of the Dynamic Chemical Process Based on the Optimized CNN-LSTM Network.

Deep learning provides new ideas for chemical process fault diagnosis, reducing potential risks and ensuring safe process operation in recent years. To address the problem that existing methods have difficulty extracting the dynamic fault features of a chemical process, a fusion model (CS-IMLSTM) based on a convolutional neural network (CNN), squeeze-and-excitation (SE) attention mechanism, and improved long short-term memory network (IMLSTM) is developed for chemical process fault diagnosis in this paper. First, an extended sliding window is utilized to transform data into augmented dynamic data to enhance the dynamic features.

[Clinical Investigation of Key Parameter Range of AMG Muscle Relaxant Monitor].

The accelerometry(AMG) muscle relaxant monitor is the most widely used quantitative muscle relaxant monitor to assess the degree of neuromuscular at present. In this study, the ulnar nerve was stimulated by using train of four stimulation(TOF) mode of the AMG muscle relaxant monitor, and the movement of the adductor pollicis muscle was monitored. In this way, the distribution range of key parameters (acceleration peak value, response time, and TOF ratio) of the adductor pollicis muscle during the use of muscle relaxant in clinical practice is analyzed and will provide a practical basis for the development and improvement of the muscle relaxant monitor.

Finite-time generalized synchronization of non-identical fractional order chaotic systems and its application in speech secure communication.

This paper focuses on the finite-time generalized synchronization problem of non-identical fractional order chaotic (or hyper-chaotic) systems by a designing adaptive sliding mode controller and its application to secure communication. The effects of both disturbances and model uncertainties are taken into account. A novel fractional order integral sliding mode surface is designed and its stability to the origin is proved in a given finite time.

Hydrogen in Patients With Corticosteroid-Refractory/Dependent Chronic Graft-Versus-Host-Disease: A Single-Arm, Multicenter, Open-Label, Phase 2 Trial.

Chronic graft-versus-host-disease (cGVHD) is the leading cause of late non-relapse mortality after allogeneic hematopoietic stem cell transplantation(HSCT). There is no standard therapy for patients refractory or dependent to corticosteroid treatment. We hypothesized that hydrogen may exert therapeutic effects on cGVHD patients with few side effects.

Fatty-acid Profiles and Fingerprints of Seven Types of Fish Roes as Determined by Chemometric Methods.

The fatty acids in seven species of fish roes were determined by GC-MS in combination with principal component and cluster analyses in order to derive their fatty-acid profiles and fingerprints. Twenty-three common chromatography peaks were identified in the fatty-acid fingerprints of the seven fish roes. A total of 19 typical fatty acids were identified in the fish roes studied.

Hematopoietic Stem Cells and Mesenchymal Stromal Cells in Acute Radiation Syndrome.

With the extensive utilization of radioactive materials for medical, industrial, agricultural, military, and research purposes, medical researchers are trying to identify new methods to treat acute radiation syndrome (ARS). Radiation may cause injury to different tissues and organs, but no single drug has been proven to be effective in all circumstances. Radioprotective agents are always effective if given before irradiation, but many nuclear accidents are unpredictable.

Extensive multifocal and pleomorphic pulmonary lesions in Waldenström macroglobulinemia: A case report.

Background: Waldenström macroglobulinemia (WM) is a type of small lymphocytic lymphoma that mainly affects the bone marrow, spleen, and lymph nodes. A subset of patients with WM demonstrates extramedullary involvement (4.4%), and the most frequent extramedullary disease site involved is the lungs (30%).

Facile Synthesis of Cobalt Oxide as an Efficient Electrocatalyst for Hydrogen Evolution Reaction.

Hydrogen evolution reaction (HER) is receiving a lot of attention because it produces clean energy hydrogen. Catalyst is the key to the promotion and application of HER. However, the precious metal catalysts with good catalytic performance are expensive, and the preparation process of non-precious metal catalysts is extremely complicated.

Medical Application of Hydrogen in Hematological Diseases.

Hydrogen gas has been reported to have medical efficacy since the 1880s. Still, medical researchers did not pay much attention to hydrogen gas until the 20th century. Recent research, both basic and clinical, has proven that hydrogen is an important physiological regulatory factor with antioxidative, anti-inflammatory, and antiapoptotic effects.

[Measures for Maintaining the Vitality of Peripheral Blood Hematopoietic Stem Cells in vitro].

Objective: To explore the maintaining measures for the vitality of hematopoietic stem cells (HSC) in vitro, so as provide technical support for ultra long distance transport of HSC collected from unrelated donors.

Methods: Peripheral blood hematopoietic stem cells (PBHSC) were treated by different methods according to various groups, then stored at 4 ℃ in the refrigerator. The percentage of CD34 cells, relative cell activity, relative cell proliferation rate, relative colony-forming rate, oxygen fraction and intracellular reactive oxygen species (ROS) were detected at 0, 24, 48 and 72 h after storage of PBHSC respectively.

Trace Element Accumulation and Tissue Distribution in the Purpleback Flying Squid Sthenoteuthis oualaniensis from the Central and Southern South China Sea.

Sthenoteuthis oualaniensis is a species of cephalopod that is becoming economically important in the South China Sea. As, Cd, Cr, Cu, Hg, Pb, and Zn concentrations were determined in the mantle, arms, and digestive gland of S. oualaniensis from 31 oceanographic survey stations in the central and southern South China Sea.

Treatment of newly diagnosed B-cell origin primary CNS lymphoma with systemic R-IDARAM chemotherapy and intrathecal immunochemotherapy.

Background: Primary central nervous system lymphoma (PCNSL) is a rare subtype of non-Hodgkin's lymphoma (NHL). The aim was to evaluate response rate, progression free survival (PFS), overall survival (OS), and toxicity in PCNSL after systemic R-IDARAM and intrathecal immunochemotherapy with deferred radiotherapy.

Results: The response rate was 94% with 17 (89%) complete responses and 1 (5%) partial responses.

Quantitative Detection of ID4 Gene Aberrant Methylation in the Differentiation of Myelodysplastic Syndrome from Aplastic Anemia.

Background: The diagnosis of myelodysplastic syndrome (MDS), especially hypoplastic MDS, and MDS with low blast counts or normal karyotype may be problematic. This study characterized ID4 gene methylation in patients with MDS and aplastic anemia (AA).

Methods: The methylation status of ID4 was analyzed by bisulfite sequencing polymerase chain reaction (PCR) and quantitative real-time methylation-specific PCR (MethyLight PCR) in 100 patients with MDS and 31 patients with AA.

Clinical implications of the quantitative detection of ID4 gene methylation in myelodysplastic syndrome.

Background: Myelodysplastic syndrome (MDS) eventually transforms into acute leukemia (AL) in about 30% of patients. Hypermethylation of the inhibitor of DNA binding 4 (ID4) gene may play an important role in the initiation and development of MDS and AL. The aim of this study was to quantitatively assess ID4 gene methylation in MDS and to establish if it could be an effective method of evaluating MDS disease progression.

Myelodysplastic syndrome with neutrophilic panniculitis: A report of two cases and a literature review.

Myelodysplastic syndrome (MDS) associated with neutrophilic panniculitis (NP) is rare. To the best of our knowledge, there are only five previously reported cases of MDS associated with NP, consisting of four adults and a young male. The present study reviews the literature of the previously reported cases and presents two case reports of adult male patients who were initially diagnosed as MDS.

Combined treatment of rituximab, idarubicin, dexamethasone, cytarabine, methotrexate with radiotherapy for primary central nervous system lymphoma.

The overall response rates and long-term survival of primary central nervous system lymphoma (PCNSL) are still significantly inferior to the results achieved in similar subtypes of extranodal non-Hodgkin's lymphoma. It is clearly necessary to investigate new therapeutic methods on PCNSL. We encountered three patients histologically documented PCNSL as diffuse large B-cell lymphoma (DLBCL).

The epigenetically-regulated miR-663 targets H-ras in K-562 cells.

miR-663 is a tumour suppressor that is potentially regulated by modification of CpG islands. Whether aberrant methylation is one of the reasons for miR-663 down-regulation in some malignant cells and whether miR-663 targets oncogenes warrants further research. In the present study, we report that the CpG islands in the upstream region of pre-miR-663 are aberrantly methylated in the k-562 cell line and in the white blood cells of some chronic myelogenous leukaemia patients, and also that H-ras is one of the genes targeted by miR-663.

Association between lymphoma prognosis and aberrant methylation of ID4 and ZO-1 in bone marrow and paraffin-embedded lymphoma tissues of treatment-naive patients.

The aim of the present study was to investigate the association between lymphoma prognosis and aberrant methylation of inhibitor of DNA binding factor 4 (ID4) and tight junction protein 1 (ZO-1) genes in samples isolated from the bone marrow and paraffin-embedded lymphoma tissues of treatment-naive lymphoma patients. The bone marrow biopsy and paraffin-embedded lymphoma tissue samples from treatment-naive lymphoma patients were obtained, along with corresponding control samples from subjects without lymphoma and from lymph nodes of chronic cholecystitis and reactive lymphadenitis patients. Methylation-specific PCR (MSP) reactions were performed to analyze the methylation status on the promoter regions of ID4 and ZO-1.