Publications by authors named "Jiamei Jia"
Article Synopsis
- Glioblastoma multiforme (GBM) is a highly lethal brain tumor with limited treatment options, and sophocarpine, an alkaloid, shows potential as an anti-tumor agent.
- In experiments, sophocarpine effectively inhibited the growth, migration, and proliferation of GBM cells while inducing apoptosis and cell cycle arrest.
- The study revealed that sophocarpine works through the PTEN/PI3K/Akt signaling pathway, making it a promising candidate for GBM therapy.
Glioblastoma (GBM) is a human malignant tumor with low survival and high recurrence rate. Angelicin, an active furanocoumarin compound, has been reported to possess potential antitumor activity towards various malignancies. However, the effect of angelicin on GBM cells and its mechanism are still unclear.
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