Dirigent (DIR) proteins are key regulators of lignin and lignan biosynthesis and play critical roles in plant hormone responses, abiotic stress tolerance, and growth and development. This study identified and characterized 47 genes in Moso bamboo, classifying them into three groups. Phylogenetic and comparative analyses revealed strong evolutionary conservation, with the Moso bamboo genes being most closely related to those in rice and maize.
View Article and Find Full Text PDFThe Life's Essential 8 (LE8) is a novel indicator of cardiovascular health proposed by the American Heart Association. While numerous studies have demonstrated its guiding value in chronic diseases, research on its role in lung function remains limited. This study utilized data from the National Health and Nutrition Examination Surveys (NHANES 2007-2012), which included comprehensive measurements of lung function, diet, physical activity, nicotine exposure, sleep patterns, body mass index (BMI), blood glucose, blood pressure, blood lipids, and relevant covariates.
View Article and Find Full Text PDFObjective: To investigate the value of routine T2-weighted magnetic resonance imaging (MRI) and contrast-enhanced magnetic resonance angiography (CE-MRA) sequences in locating the fistula level of spinal arteriovenous fistula (SAVF).
Methods: Retrospectively analyzed the radiological findings of patients with SAVF diagnosed by surgery from May 2018 to September 2024. All patients completed spinal CE-MRA and routine T2-weighted MRI.
Background: and purpose: The investigation of functional plasticity and remodeling of the brain in patients with retinal detachment (RD) has gained increasing attention and validation. However, the precise alterations in the topological configuration of dynamic functional networks are still not fully understood. This study aimed to investigate the topological structure of dynamic brain functional networks in RD patients.
View Article and Find Full Text PDFBackground: Play is an indispensable and meaningful activity in children's daily life. Research has shown that autistic children often exhibit differences in play development. The core traits of autism, such as distinct patterns in social interaction and communication, focused interests, and repetitive behaviors, frequently manifest in their play.
View Article and Find Full Text PDFCompared to the surface defect detection of industrial products produced according to specified processes, the detection of surface defects in naturally grown red jujubes poses unique and significant challenges for researchers. The high diversity of surface defects, subtle distinctions from the background, low contrast, varying scales, and the presence of high levels of noise in images are among the factors that greatly amplify the complexity of defect detection tasks. Existing methods show some deficiencies in addressing these issues, mainly due to insufficient feature extraction capabilities and overly complex network structures, leading to limitations in model efficiency and practical application performance.
View Article and Find Full Text PDFObjective: We examined the relationships between the structural connectome and temporomandibular disorders (TMDs).
Methods: Bidirectional Mendelian randomization analyses were conducted using Genome-wide association studies data on the structural connectome and TMDs.
Results: Positive associations with TMD risk were found for white matter structural connectivity from the left hemisphere limbic network to putamen, left hemisphere salience_ventral attention network to caudate, right hemisphere visual network to thalamus, and right hemisphere salience_ventral attention network to right hemisphere control network, while negative associations were observed for connectivity from the left hemisphere control and somatomotor networks to pallidum, left hemisphere somatomotor network to right hemisphere dorsal attention network, and right hemisphere somatomotor network to hippocampus (< 0.
Background: Existing studies predominantly focused on the relationship between periodontitis and type 2 diabetes mellitus (T2DM), with limited data on the association between periodontitis and type 1 diabetes mellitus (T1DM). This study aimed to examine the impact of T1DM and periodontitis on the subgingival microbiome and levels of advanced glycation end-products (AGEs).
Methods: Samples were collected from four groups: T1DM, periodontitis (P), T1DM with periodontitis (DP), and periodontally and systemically healthy controls (Control).
Background: Telomere length is closely associated with the occurrence and development of cardiovascular and other diseases. Monocyte to high-density lipoprotein cholesterol ratio (MHR) is a novel indicator of inflammation, oxidative stress, and metabolic syndrome, with some predictive ability for related disease risks in clinical practice. However, there is no research on the correlation between these two factors.
View Article and Find Full Text PDFObjective: Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by increasing prevalence, diverse impairments, and unclear origins and mechanisms. To gain a better grasp of the origins of ASD, it is essential to identify the most distinctive structural brain abnormalities in individuals with ASD.
Methods: A Multi-Stage Progressive Feature Refinement Approach was employed to identify the most pivotal structural magnetic resonance imaging (MRI) features that distinguish individuals with ASD from typically developing (TD) individuals.
Background: The incidence of community-acquired empyema caused by the group (SAG) has been on the rise in the 2020s. To the best of our knowledge, while empyema caused individually by either strain has been reported, there are no reports on empyema caused by concurrent infection with these two strains. Here, we report for the first time empyema caused by concurrent infection with and (both SAG species) in a postoperative patient who had been treated for floor of the mouth carcinoma.
View Article and Find Full Text PDFWith the rapid popularity of online social media, recommendation systems have increasingly harnessed social relations to enhance user-item interactions and mitigate the data sparsity issue. Beyond social connections, the semantic relatedness among items has emerged as a crucial factor in comprehending their inherent connections. In this work, we propose a novel Multi-view Contrastive learning framework for Social Recommendation, named MultiCSR.
View Article and Find Full Text PDFAqueous Zn battery is promising for grid-level energy storage due to its high safety and low cost, but dendrite growth and side reactions at the Zn metal anode hinder its development. Designing Zn with (002) orientation improves the stability of the Zn anode, yet grain boundaries remain susceptible to corrosion and dendrite growth. Addressing these intergranular issues is crucial for enhancing the electrochemical performance of (002)-textured Zn.
View Article and Find Full Text PDFGenerally, pelvic osteosarcoma has a worse prognosis compared with limb osteosarcoma. This study aims to create and validate a new nomogram for predicting the prognosis of pelvic osteosarcoma. Clinical data of 62 patients derived from the Surveillance, Epidemiology, and End Results (SEER) database and 31 Chinese patients diagnosed with pelvic osteosarcoma were gathered.
View Article and Find Full Text PDFGallbladder cancer (GBC) is characterized by a high degree of malignancy and a poor prognosis. This study revealed that circEZH2 was frequently upregulated in GBC tissues and correlated with advanced tumor-node-metastasis (TNM) stage in GBC patients. and experiments confirmed that circEZH2 promoted the proliferation and inhibited the ferroptosis of GBC.
View Article and Find Full Text PDFUrinary incontinence is a common complication in stroke survivors for whom new interventions are needed. This study investigated the therapeutic effect of low-frequency (LF) repeated transcranial magnetic stimulation (rTMS) on the contralesional primary motor cortex (M1) in patients with poststroke urinary incontinence (PSI). A total of 100 patients were randomly assigned to the rTMS group or sham-rTMS group on basis of the intervention they received.
View Article and Find Full Text PDFAim: To evaluate the effectiveness and safety of nutritional interventions (i.e. nutritional support, dietary patterns and dietary supplements) on cognitive function in cancer survivors.
View Article and Find Full Text PDFProteins and peptides play vital roles in different biological processes . As a dynamic hydrolysis system, milk is rich in proteins and proteases and provides a constant supply of endogenous bioactive peptides to newborn mammals. Previous studies have primarily focused on researching bioactive peptides by adding exogenous enzymes to milk samples.
View Article and Find Full Text PDFThe traditional Chinese medicine (TCM) industry in China exhibits significant regional disparities in health service utilization, the underlying reasons for which are yet to be fully explored. This study employs Geodetector models to analyze the factors affecting TCM service utilization, providing the first examination of spatial distribution patterns and influencing factors for both TCM outpatient (TCMOSU) and inpatient services (TCMISU). The findings of this study reveal spatial disparities across China's provinces, showing a prevalence of TCMOSU in the east and TCMISU decreasing from southwest to northeast.
View Article and Find Full Text PDFJ Phys Condens Matter
June 2024
Perovskite solar cells (PSCs) have garnered significant attention owing to their highly power conversion efficiency (PCE) and cost-effectiveness. Traditionally, screening for PSCs with superior photovoltaic parameters relies on resource-intensive trial-and-error experiments. Nowadays, time-saving machine learning (ML) techniques serve as an artificial intelligence approach to expedite the prediction of photovoltaic parameters using accumulated research datasets.
View Article and Find Full Text PDFPurpose: To investigate the causality between periodontitis and non-alcoholic fatty liver disease (NAFLD) using a two-sample bidirectional Mendelian randomisation (MR) analysis.
Materials And Methods: Genetic variations in periodontitis and NAFLD were acquired from genome-wide association studies (GWAS) using the Gene-Lifestyle Interaction in Dental Endpoints, a large-scale meta-analysis, and FinnGen consortia. Data from the first two databases were used to explore the causal relationship between periodontitis and NAFLD ("discovery stage"), and the data from FinnGen was used to validate our results ("validation stage").
The bacterial flagellum is an elongated filament that protrudes from the cell and is responsible for bacterial motility. It can also be a pathogen-associated molecular pattern (PAMP) that regulates the host immune response and is involved in bacterial pathogenicity. In contrast to motile bacteria, the Brucella flagellum does not serve a motile purpose.
View Article and Find Full Text PDFChina faces challenges in meeting the World Health Organization (WHO)'s target of reducing hepatitis B virus (HBV) infections by 95% using 2015 as the baseline. Using Global Burden of Disease (GBD) 2019 data, joinpoint regression models were used to analyse the temporal trends in the crude incidence rates (CIRs) and age-standardized incidence rates (ASIRs) of acute HBV (AHBV) infections in China from 1990 to 2019. The age-period-cohort model was used to estimate the effects of age, period, and birth cohort on AHBV infection risk, while the Bayesian age-period-cohort (BAPC) model was applied to predict the annual number and ASIRs of AHBV infections in China through 2030.
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