Analysis and regulation of driving behavior in the entrance zone of freeway tunnels: Implementation of visual guidance systems in China.

In China, visual guidance systems are commonly used in tunnels to optimize the visual reference system. However, studies focusing specifically on visual guidance systems in the tunnel entrance zone are limited. Hence, a driving simulation test is performed in this study to quantitatively evaluate the effectiveness of (i) visual guidance devices at different vertical positions (pavement and roadside) and (ii) a multilayer visual guidance system for regulating driving behavior in the tunnel entrance zone.

Single-cell transcriptome sequencing of B-cell heterogeneity and tertiary lymphoid structure predicts breast cancer prognosis and neoadjuvant therapy efficacy.

Background: Breast cancer (BC) is a highly heterogeneous disease, and although immunotherapy has recently increased patient survival in a number of solid and hematologic malignancies, most BC subtypes respond poorly to immune checkpoint blockade therapy (ICB). B cells, particularly those that congregate in tertiary lymphoid structures (TLS), play a significant role in antitumour immunity. However, B-cell heterogeneity at single-cell resolution and its clinical significance with TLS in BC need to be explored further.

Terahertz difference-frequency-generation quantum cascade lasers on silicon with wire grid current injectors.

We propose the concept and experimentally verify the operation of terahertz quantum cascade laser sources based on intra-cavity Cherenkov difference-frequency generation on a silicon substrate with the current injection layer configured as a metal wire grid. Such a current injector configuration enables high transmission of TM-polarized terahertz radiation into the silicon substrate while simultaneously providing a low-resistivity metal contact for current injection.

Preparation of Linalool/Polycaprolactone Coaxial Electrospinning Film and Application in Preserving Salmon Slices.

A linalool/polycaprolactone (LL/PCL) antibacterial film was prepared by using a coaxial electrospinning process, and its physical and chemical properties were characterized. The antibacterial film was formed into an active antibacterial gasket, and its effect on salmon preservation was analyzed. The results show that the LL/PCL nanofiber membrane had a well-developed microstructure, and the fiber surface was smooth and uniform.

The study of correlation between nomogram prediction of uric acid and different chemotherapy regimens in breast cancer patients.

Background: High levels of serum uric acid (SUA) are associated with a poor survival rate of breast cancer. Meanwhile, a sharp increase in SUA after chemotherapy may lead to tumor lysis syndrome (TLS). We created and validated a nomogram to help doctors better manage the patient's SUA level ahead of time in this study.

Preparation of pH-sensitive polylactic acid-naringin coaxial electrospun fiber membranes for maintaining and monitoring salmon freshness.

Seafood spoilage can be prevented by inhibiting the quorum sensing (QS) system between bacteria. However, membrane materials combining freshness indicators with QS inhibition features have rarely been reported. Therefore, in this study, pH-sensitive polylactic acid-naringin coaxial electrospun fibers capable of maintaining and monitoring freshness were prepared and investigated.

Widely tunable eye-safe optical parametric oscillator with noncollinear phase-matching in a ring cavity.

An effective method for wavelength tuning in an optical parametric oscillator (OPO) was proposed using noncollinear phase-matching (PM) in a ring cavity. This method was particularly useful for noncritically phase-matched (NCPM) KTP/KTA OPOs where changing the crystal orientation or working temperature is ineffective. A wide tuning range in the eye-safe band from 1572.

Compact and stable high-repetition-rate terahertz generation based on an efficient coaxially pumped dual-wavelength laser.

A compact and stable terahertz (THz) source is demonstrated based on difference frequency generation (DFG) pumped by an efficient dual-wavelength acousto-optic (AO) Q-switched solid-state Nd:YLF laser with composite gain media (a-cut and c-cut) in the coaxial pumping configuration. Optimal power ratio and pulse synchronization of the orthogonal polarized 1047/1053 nm dual-wavelength laser could be realized by varying the pump focusing depth and/or pump wavelength. The total power of 2.

Widely-tunable high-repetition-rate terahertz generation in GaSe with a compact dual-wavelength KTP OPO around 2 μm.

A compact efficient high-repetition-rate doubly-resonant dual-wavelength KTP optical parametric oscillator (OPO), with output power up to 3.65 W and tuning ranges of 2.088-2.