Publications by authors named "Jiale Quan"

Article Synopsis
  • Neoantigen vaccines show potential for cancer treatment, but not all neoantigens effectively activate CD8 T cells due to poor recognition of CD4 epitopes.
  • To address this, researchers developed a DNA-coupled nitrated T helper cell epitope nanoparticle (DCNP) to enhance CD8 T cell activation and improve neoantigen responses.
  • The DCNP platform significantly improved the delivery of neoantigens and adjuvants to immune cells, leading to strong and lasting anti-tumor effects, indicating its potential in personalized cancer vaccines.
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In this paper, we propose a method to generate multi-depth phase-only holograms using stochastic gradient descent (SGD) algorithm with weighted complex loss function and masked multi-layer diffraction. The 3D scene can be represented by a combination of layers in different depths. In the wave propagation procedure of multiple layers in different depths, the complex amplitude of layers in different depths will gradually diffuse and produce occlusion at another layer.

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Low-dimensional ternary copper iodide metal halide with strong quantum confinement effects has made great progress in optoelectronic fields. However, efficient regulation of anisotropic growth of metal halides single crystal still remains a great challenge. Herein, 2 cm size CsCu I single crystals with tunable aspect ratio and the trap states (n ) as low as 5.

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With the widespread use of magneto-sensitive elements, magnetic shields are an important part of electronic equipment, ultra-sensitive atomic sensors, and in basic physics experiments. Particularly in Spin-exchange relaxation-free (SERF) co-magnetometers, the magnetic shield is an important component for maintaining the SERF state. However, the inherent noise of magnetic shield materials is an important factor limiting the measurement sensitivity and accuracy of SERF co-magnetometers.

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Background: Vein of Galen Malformations (VGAM) and bilateral idiopathic occlusion of the sigmoid sinuses are extremely rare. We report a child with Vein of Galen Aneurysmal Malformation (VGAM) and Idiopathic bilateral sigmoid sinus occlusion simultaneously, and managed through endovascular therapy in one session. This case highlights the coexistence of the lesions, as well as the one-session technical feasibility and good clinical outcome for endovascular treatment.

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Objective: To systematically assess the efficacy and safety of dexmedetomidine as an anaesthesia adjuvant for cleft lip and palate (CLP) repair in children.

Design: Systematic review and meta-analysis.

Data Sources: PubMed, Embase, Cochrane, China National Knowledge Infrastructure (CNKI), China Science and Technology Journal Database (VIP) and Wanfang (up to October 2020).

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Tyrosine nitration of proteins is one of the most important oxidative post-translational modifications in vivo. A major obstacle for its biochemical and physiological studies is the lack of efficient and chemoselective protein tyrosine nitration reagents. Herein, we report a generalizable strategy for light-controlled protein tyrosine nitration by employing biocompatible dinitroimidazole reagents.

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Background And Purpose: The safety and effectiveness of endovascular treatment for non-Galenic pial arteriovenous fistula (NGPAVF) is inadequately known. The aim of this study is to explore the role of endovascular embolisation for curative treatment of NGPAVF.

Materials And Methods: Patients with NGPAVF underwent endovascular treatment from January 2011 to November 2019 in our institution were retrospectively reviewed.

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