Corrigendum: The possibility of clinical bonding between metal/ceramic brackets to zirconia: study.

[This corrects the article DOI: 10.3389/fbioe.2024.

Electrochemical Oxidative (4 + 2) Cyclization of Anilines and -Phenylenediamines for the Synthesis of Phenazines.

Phenazines, crucial constituents of nitrogen-containing heterocycles, widely exist in functional compounds. Herein, we report an anodic oxidative (4 + 2) cyclization between anilines and -phenylenediamines for the uniform construction of phenazines in a simple undivided cell. Dual C-H amination followed by oxidation represents an outstanding step and atom efficiency.

Electro-oxidative three-component cascade coupling of isocyanides with elemental sulfur and amines for the synthesis of 2-aminobenzothiazoles.

2-Aminobenzothiazoles are commonly encountered in various functional compounds. Herein, we disclose an electro-oxidative three-component reaction for the effective synthesis of 2-aminobenzothiazoles under mild conditions, utilizing non-toxic and abundant elemental sulfur as the sulfur source. Both aliphatic amines and aryl amines demonstrate good compatibility at room temperature, highlighting the broad functional group tolerance of this approach.

The possibility of clinical bonding between metal/ceramic brackets to zirconia: study.

The present study aimed to assess the bond strength and durability of six bonding agents concerning their application to metal or ceramic brackets and zirconia. Six resin cement bonding agents (XT, XTS, RSBU, RGBU, SBPM, and GMP) were chosen for this investigation. Specimens were either stored in distilled water at 37°C for 24 h or subjected to 5,000 thermocycles before conducting a Shear Bond Strength (SBS) test.

Photoredox radical cyclization reaction of -vinylaryl isocyanides with acyl chlorides to access 2,4-disubstituted quinolines.

We herein report an efficient photoredox radical cyclization reaction of -vinylaryl isocyanides with acyl chlorides to access a wide range of 2,4-disubstituted quinolines. Preliminary mechanism experiment results suggested that this reaction was initiated by an acyl radical generated from acyl chlorides through a single-electron-transfer (SET) process. This transformation showed good substrate suitability and functional group compatibility at room temperature.

The color stability, water sorption, and solubility of ten composite resins.

Objectives: This study aims to evaluate the color stability and related properties including water sorption and solubility of ten light-cured composite resins in different solutions.

Methods: A total of 10 composite resins were BeautifilⅡ(B2) and Ceram. X One Universal (CXU), Charisma (CS), Charisma Diamond (CD), Denfil (DF), DX.

Evaluation of the Color Stability, Water Sorption, and Solubility of Current Resin Composites.

This study aims to assess the color stability, water sorption, and solubility of 11 resin composites as commercially available dental products. Twenty samples (10 mm in diameter and 2 mm in thickness) of each material were fabricated using a customized silicone mold, followed by immersion in each of curry, coffee, wine, and distilled water for 28 days (n = 5). Baseline shade and color changes (ΔE) were measured using a reflection spectrophotometer.

Shear bond strength of different bonding agents to orthodontic metal bracket and zirconia.

This study aimed to evaluate the shear bond strength (SBS) of four bonding agents used to bond metal brackets to zirconia under different storage conditions. Four bonding agents were used [FLC: (Fuji ORTHO LC), XT: (Transbond XT), RUC-SBU: (Rely X Ultimate Clicker Adhesive Resin Cement+Single Bond Universal), and RUC-GBU: (Rely X Ultimate Clicker Adhesive Resin Cement+Gluma Bond Universal)] to bond two types of metal brackets (PT/3M) to zirconia surfaces, and they were stored in water at 37ºC for 24 h or thermocycling for 3,000 cycles. The SBS data of RUC-SBU and RUC-GBU using PT brackets were significantly higher than those of 3M brackets before and after thermocycling.

FRK inhibits glioblastoma progression via phosphorylating YAP and inducing its ubiquitylation and degradation by Siah1.

Background: We previously report that yes-associated protein (YAP), the core downstream effector of Hippo pathway, promotes the malignant progression of glioblastoma (GBM). However, although classical regulatory mechanisms of YAP are well explored, how YAP is modulated by the Hippo-independent manner remains poorly understood. Meanwhile, the nonreceptor tyrosine kinase Fyn-related kinase (FRK), which exhibits low expression and possesses tumor suppressor effects in GBM, is reported to be involved in regulation of protein phosphorylation.

Rapid regulations of metabolic reactions in Escherichia coli via light-responsive enzyme redistribution.

Protein-based condensates have been proposed to accelerate biochemical reactions by enriching reactants and enzymes simultaneously. Here, we engineered those condensates into a photo-activated switch in Escherichia coli (PhASE) to regulate enzymatic reactions via tuning the spatial correlation of enzymes and substrates. In this system, scaffold proteins undergo liquid-liquid phase separation (LLPS) to form light-responsive compartments.

Enhancing the Stability of the Resin-Dentin Bonding Interface with Ag- and Zn-Exchanged Zeolite A.

Enhancing the stability of the resin-dentin bonding interface simultaneously improving the antibacterial, mechanical, and adhesive properties of a dental adhesive is the key to prolonging the longevity of dental restoration for caries treatment. Herein, we present the stabilization effect of Ag- and Zn-exchanged zeolite A (denoted as Ag-A and Zn-A, respectively) on the resin-dentin bonding interface. Ag-A and Zn-A zeolites exhibited sustained ion release capability, outstanding biocompatibility to L929 cells (<2 mg/mL), and excellent antibacterial ability to (minimum inhibitory concentration: 100 μg/mL for Ag-A and 200 μg/mL for Zn-A).

Pulpal response to mineral trioxide aggregate containing phosphorylated pullulan-based capping material.

This study aimed to evaluate the pulpal responses of monkey's pulp after direct pulp capping (DPC) with the novel mineral trioxide aggregate containing phosphorylated pullulan-based material (MTAPPL). Seventy-two teeth were randomly divided into four groups: MTAPPL; Nex-Cem MTA (NX); TheraCal LC (TH); and Dycal (DY). Histopathological changes in the pulps were observed at days 3, 7 and 70.

[Effects of adhesive and primer on the bonding strength of zirconia to resin cement].

Objective: This study aimed to compare the effects of water storage treatment and thermal cycling on the shear bond strength (SBS) of three self-adhesive dual-cure resin cements.

Methods: Six cubic zirconia specimens with side length of 2 cm were obtained by cutting and sintering. Three self-adhering dual-cure resin cements (i.

Effect of air-blowing temperature and water storage time on the bond strength of five universal adhesive systems to dentin.

The purpose of this study was to evaluate the air-blowing temperature and water storage time on the micro-tensile bond strength (μTBS) of five universal adhesive systems to dentin. The bond strength with two different air-blowing temperatures (60±2ºC and 23±2ºC) was measured after water storage at 37ºC for 24 h and 100 days respectively. The fracture surface on dentin side was observed by scanning electron microscope (SEM).

Lithium Nitrate Regulated Sulfone Electrolytes for Lithium Metal Batteries.

The electrolytes in lithium metal batteries have to be compatible with both lithium metal anodes and high voltage cathodes, and can be regulated by manipulating the solvation structure. Herein, to enhance the electrolyte stability, lithium nitrate (LiNO ) and 1,1,2,2-tetrafuoroethyl-2',2',2'-trifuoroethyl(HFE) are introduced into the high-concentration sulfolane electrolyte to suppress Li dendrite growth and achieve a high Coulombic efficiency of >99 % for both the Li anode and LiNi Mn Co O (NMC811) cathodes. Molecular dynamics simulations show that NO participates in the solvation sheath of lithium ions enabling more bis(trifluoromethanesulfonyl)imide anion (TFSI ) to coordinate with Li ions.

Competing Dehalogenation versus Borylation of Aryl Iodides and Bromides under Transition-Metal-Free Basic Conditions.

In this work, selectivity-controllable base-promoted transition-metal-free borylation and dehalogenation of aryl halides are described. Under the conditions of borylation, the dehalogenation which emerges as a competitive side reaction has been well-controlled by carefully controlling the borylation conditions. On the other hand, the dehalogenation using benzaldehyde as a hydrogen source has also been accomplished.

Activation of STAT1 by the FRK tyrosine kinase is associated with human glioma growth.

Purpose: Glioma is a highly aggressive and lethal brain tumor. Signal transducers and activators of transcription (STAT) pathway are widely implicated in glioma carcinogenesis. Our previous study found that the Fynrelated kinase (FRK) gene, plays as a tumor suppressor in the development and progression of glioma.

Copper-catalyzed oxidative benzylic C-H cyclization via iminyl radical from intermolecular anion-radical redox relay.

Base-promoted C-H cleavage without transition metals opens a practical alternative for the one based on noble metals or radical initiators. The resulting carbanion can pass through radical addition to unsaturated bonds like C-N or C-C triple bonds, in which stoichiometric oxidants are needed. When in situ C-H cleavage meets catalytic carbanion-radical relay, it turns to be challenging but has not been accomplished yet.

Effect of air-blowing time and long-term storage on bond strength of universal adhesives to dentin.

Objectives: To evaluate the effects of air-blowing time and storage time on microtensile bond strength (μTBS) of universal adhesives to dentin.

Materials And Methods: Ninety flat dentin surfaces from extracted human third molars were bonded with three universal adhesives (Clearfil Universal Bond-CU; G-Premio Bond-GP; Scotchbond Universal Adhesives-SB). Bonded dentin surfaces were air-dried for 5 s, 15 s, or 30 s followed by resin composite built-up.

Golgi Phosphoprotein 3 Promotes Wls Recycling and Wnt Secretion in Glioma Progression.

Background/aims: Golgi phosphoprotein 3 (GOLPH3) plays pro-malignancy roles in several types of cancer. However, the molecular mechanism underlying GOLPH3 promoting tumor progression remains poorly understood.

Methods: The expression of GOLPH3 and Wntless (Wls) in glioma tissues was examined by western blotting and immunohistochemistry.

Electrochemical Properties of the LiNiCoMnO Cathode Material Modified by Lithium Tungstate under High Voltage.

An amount (5 wt %) of lithium tungstate (LiWO) as an additive significantly improves the cycle and rate performances of the LiNiCoMnO electrode at the cutoff voltage of 4.6 V. The 5 wt % LiWO-mixed LiNiCoMnO electrode delivers a reversible capacity of 199.

GOLPH3 promotes glioma progression via facilitating JAK2-STAT3 pathway activation.

Introduction: Our recent work reported that GOLPH3 promotes glioma progression via inhibiting endocytosis and degradation of EGFR. The current study aimed to explore the potential regulating mechanism of GOLPH3 on JAK2-STAT3 signaling, a downstream effector of EGFR, in glioma progression.

Methods: The expression of JAK2, STAT3 and GOLPH3 in glioma tissues was detected by western blotting, tissue microarray and immunohistochemistry.

Effect of air-blowing duration on the bond strength of current one-step adhesives to dentin.

Objectives: To evaluate the influence of different air-blowing durations on the micro-tensile bond strength (μTBS) of five current one-step adhesive systems to dentin.

Methods: One hundred and five caries-free human molars and five current one-step adhesive systems were used: ABU (All Bond Universal, Bisco, Inc.), CUB (CLEARFIL™ Universal Bond, Kuraray), GPB (G-Premio BOND, GC), OBA (OptiBond All-in-one, Kerr) and SBU (Scotchbond Universal, 3M ESPE).

Expression and significance of Hippo/YAP signaling in glioma progression.

Dysregulation of Hippo/YAP signaling leads to aberrant cell growth and neoplasia. Although the roles and regulation of Hippo/YAP signaling were extensively studied in cancer biology recently, study systematically checking the expression pattern of core components of this pathway at the tumor tissue level remains lacking. In this study, we thoroughly examined the profile of core components of Hippo/YAP signaling in patient specimens both at the mRNA and at protein levels.