The Pathogenic Effects of on the Proliferation, Osteogenic Differentiation, and Transcriptome of Osteoblasts.

As one of the most common oral diseases, periodontitis is closely correlated with tooth loss in middle-aged and elderly people. () contributes to periodontitis, but the evidence in alveolar bone loss is still unclear. In this study, cytological experiments and transcriptome analyses were performed to characterize the biological process abnormalities and the molecular changes of -stimulated osteoblasts.

Matrine enhances osteogenic differentiation of bone marrow-derived mesenchymal stem cells and promotes bone regeneration in rapid maxillary expansion.

Objective: The aim of this study was to evaluate the influence of matrine on osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells (BMSCs) as well as on bone metabolism in a rat rapid maxillary expansion (RME) model.

Methods: In in vitro experiments, rat BMSCs were adopted and cell proliferation of BMSCs was measured. Meanwhile, the osteogenic differentiation of BMSCs was detected by alkaline phosphatase (ALP) activity assay, Alizarin red S staining and gene expression.

Resveratrol rescues TNF‑α‑induced inhibition of osteogenesis in human periodontal ligament stem cells via the ERK1/2 pathway.

Periodontitis is a common inflammatory disorder affecting the tissues surrounding the teeth, which can lead to the destruction of periodontal tissue and tooth loss. Resveratrol, a natural phytoalexin, exerts multiple biological effects. For example, its anti‑inflammatory activity has been widely studied for the treatment of inflammatory bowel disease for a number of years.

[Effects and influential factors of rapid prototyping technology in dental restorations].

Purpose: To explore the effects and influential factors of rapid prototyping technology in dental restorations.

Methods: From May 2013 to November 2014 in our hospital, 120 patients were divided into experimental group and conventional group. Patients in the experimental group were treated by rapid prototyping technology, while patients in the conventional group were treated by routine methods.