Poly-Adenine Assisted Signaling Displaced Probe Ratiometric Electrochemical Aptasensor for Accurate Detection of Alzheimer's Disease Aβ Biomarkers.

Alzheimer's disease (AD) is a widely prevalent neurodegenerative condition globally, arousing significant interest in the noninvasive early detection of the disease. The concentration of amyloid β (Aβ) biomarkers in the blood is closely linked to the progression of AD, emphasizing the importance of developing a precise method for detecting these biomarkers in blood samples for early diagnosis. In this study, we developed a ratiometric electrochemical aptamer-based (EAB) biosensor for accurate detection of Aβ and Aβ.

Nucleobase-modulated copper nanomaterials with laccase-like activity for high-performance degradation and detection of phenolic pollutants.

Laccases are the most commonly used agents for the treatment of phenolic pollutants. To address the instability and high cost of natural laccases, we investigated nucleobase-modulated copper nanomaterial with laccase-like activity. Various nucleobases, including adenine, guanine, cytosine, and thymine, were investigated as templates for Cu reduction and copper nanomaterials formation due to their coordination capacity.

A Multimodel-Based Deep Learning Framework for Short Text Multiclass Classification with the Imbalanced and Extremely Small Data Set.

Text classification plays an important role in many practical applications. In the real world, there are extremely small datasets. Most existing methods adopt pretrained neural network models to handle this kind of dataset.

Guiding microscale swimmers using teardrop-shaped posts.

The swimming direction of biological or artificial microscale swimmers tends to be randomised over long time-scales by thermal fluctuations. Bacteria use various strategies to bias swimming behaviour and achieve directed motion against a flow, maintain alignment with gravity or travel up a chemical gradient. Herein, we explore a purely geometric means of biasing the motion of artificial nanorod swimmers.

Stability of two-dimensional soft quasicrystals in systems with two length scales.

The relative stability of two-dimensional soft quasicrystals in systems with two length scales is examined using a recently developed projection method, which provides a unified numerical framework to compute the free energy of periodic crystal and quasicrystals. Accurate free energies of numerous ordered phases, including dodecagonal, decagonal, and octagonal quasicrystals, are obtained for a simple model, i.e.