genotypes through gene-gene interactions with affect azathioprine-induced leukopenia in Chinese patients.

To investigate whether genotypes of , and were associated with azathioprine-induced adverse drug reaction (ADR) and had the gene-gene interactions with rs116855232 to induce leukopenia. Patients who had taken azathioprine were recruited. Genotyping of those gene was performed.

Prediction of severity and outcomes of colon ischaemia using a novel prognostic model: a clinical multicenter study.

Objective: To identify risk factors of disease severity and between mild and severe colon ischaemia (CI) patients and to improve clinical outcomes, this study aimed to explore a novel scoring model.

Methods: Retrospective analyses of hospital records between January 2009 and December 2019 were included. Clinical manifestations, mortality, Oakland score, laboratory tests, colonoscopy, and histopathology were collected.