The challenge of achieving fast and efficient separation of photogenerated carriers lies in the kinetics of photocatalytic reactions. In the present study, we employed solvothermal and surfactant-induced methods to uniformly grow BiOCl on the surface of CoS Nano-flower balls, thereby forming core-shell Schottky heterojunctions. X-ray photoelectron spectroscopy (XPS) and density functional theory (DFT) calculations demonstrated the directional transfer of electrons and the establishment of an enhanced built-in electric field during the formation of these heterojunctions.
View Article and Find Full Text PDFGel foam is vital to its applications but remains a challenge. Herein, microbial gel foam was developed for coal spontaneous combustion, which was a gel foam loaded O-consuming microbial community. The microbial gel foam had the ability to consume O and produce CO.
View Article and Find Full Text PDFThe self-absorption effect in an optically thick plasma seriously affects the spectral line intensity and the measurement accuracy of laser-induced breakdown spectroscopy (LIBS). In this work, a self-absorption correction method based on intensity self-calibration of doublet lines belonging to the same multiplet is proposed. The K/Δλ parameter and self-absorption coefficient (SA) of the doublet lines of the analytical element can be calculated based on the measured actual lines intensity ratio and the K parameters ratio.
View Article and Find Full Text PDFHomologous recombination (HR), a form of error-free DNA double-strand break (DSB) repair, is important for the maintenance of genomic integrity. Here, we identify a moonlighting protein, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), as a regulator of HR repair, which is mediated through HDAC1-dependent regulation of RAD51 stability. Mechanistically, in response to DSBs, Src signaling is activated and mediates GAPDH nuclear translocation.
View Article and Find Full Text PDFShort-term starvation (STS) during chemotherapy can block the nutrient supply to tumors and make tumor cells much more sensitive to chemotherapeutic drugs than normal cells. However, because of the diversity of starvation methods and the heterogeneity of tumors, this method's specific effects and mechanisms for chemotherapy are still poorly understood. In this study, we used HeLa cells as a model for short-term starvation and etoposide (ETO) combined treatment, and we also mimicked the short-term starvation effect by knocking down the glycolytic enzyme GAPDH to explore the exact molecular mechanism.
View Article and Find Full Text PDFClassical cavernous sinus embolism is a rare clinical finding, presented most commonly by complaints of headache, diplopia, visual field defects, facial pain, and progressive neurological deficits. Many patients exhibit symptoms of III, IV, and VI nerve palsies. We hereby report a rare case of aseptic cavernous sinus embolism developed in a 75-year-old male with primary lung cancer who presented with binocular diplopia due to unilateral third and sixth cranial nerve palsies with pupil-sparing.
View Article and Find Full Text PDFThe neurodegenerative disease spinocerebellar ataxia type 3 (SCA3; also called Machado-Joseph disease, MJD) is a trinucleotide repeat disorder caused by expansion of the CAG repeats in the gene. Here, we applied a CRISPR/Cas9-mediated approach using homologous recombination to achieve a one-step genetic correction in SCA3-specific induced pluripotent stem cells (iPSCs). The genetic correction reversed disease-associated phenotypes during cerebellar region-specific differentiation.
View Article and Find Full Text PDFBackground: This study aimed to investigate the clinical and pathological characteristics, and the recurrence and prognostic factors of borderline ovarian tumors (BOTs).
Methods: The data of 286 patients admitted to hospital and followed up for more than ten months were analyzed retrospectively to study the clinicopathological characteristics and related factors of recurrence.
Results: The median age of the patients was 42.
A calibration method based on homogeneous material for correcting laser-induced breakdown spectroscopy (LIBS) measurement-error bias in the case of dust pollution under laboratory conditions is proposed. The measured plasma spectra of the sample can be corrected by measuring the spectral integral of the homogeneous material. Thus, we can effectively minimize the dust pollution effect on LIBS and guarantee its precision.
View Article and Find Full Text PDFA novel self-absorption-free laser-induced breakdown spectroscopy (SAF-LIBS) technique is proposed to directly capture the optically thin spectral line by matching the measured doublet atomic lines intensity ratios with the theoretical one. To realize the experimental SAF-LIBS, the integration time, the fiber collection angle, and the delay time are optimized. The optically thin conditions are validated by comparing the linearity of Boltzmann plots with the traditional self-absorption (SA) correction method and evaluating the SA coefficients.
View Article and Find Full Text PDFSalinity and drought severely affect both plant growth and productivity, making the isolation and characterization of salinity- or drought-inducible promoters suitable for genetic improvement of crop resistance highly desirable. In this study, a 1468-bp sequence upstream of the translation initiation codon ATG of the promoter for ZmGAPP (maize Type-II H+-pyrophosphatase gene) was cloned. Nine 5´ deletion fragments (D1-D9) of different lengths of the ZmGAPP promoter were fused with the GUS reporter and translocated into tobacco.
View Article and Find Full Text PDFSalinity and drought often affect plant growth and crop yields. Cloning and identification of salinity and drought stress inducible promoters is of great significance for their use in the genetic improvement of crop resistance. Previous studies showed that phosphatidylinositol synthase is involved in plant salinity and drought stress responses but its promoter has not been characterized by far.
View Article and Find Full Text PDFA methodology for calibration-free wavelength modulation spectroscopy (CF-WMS) that is based upon an extensive empirical description of the wavelength-modulation frequency response (WMFR) of DFB laser is presented. An assessment of the WMFR of a DFB laser by the use of an etalon confirms that it consists of two parts: a 1st harmonic component with an amplitude that is linear with the sweep and a nonlinear 2nd harmonic component with a constant amplitude. Simulations show that, among the various factors that affect the line shape of a background-subtracted peak-normalized 2f signal, such as concentration, phase shifts between intensity modulation and frequency modulation, and WMFR, only the last factor has a decisive impact.
View Article and Find Full Text PDFPhosphate (Pi) deficiency has become a significant challenge to worldwide agriculture due to the depletion of accessible rock phosphate that is the major source of cheap Pi fertilizers. Previous research has identified a number of diverse adaptive responses to Pi starvation in the roots of higher plants. In this study, we found that accelerated axile root elongation of Pi-deprived maize plants resulted from enhanced cell proliferation.
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