ApoC3 is expressed in oocytes and increased expression is associated with PCOS progression.

Background: Polycystic ovary syndrome (PCOS) is a lifelong metabolic disorder and the most common cause of anovulatory infertility affecting women in reproductive age. Our recent study reported that apolipoprotein C3 (ApoC3) could be a potential diagnostic serum marker for metabolism disturbance in PCOS patients, but whether it is present in the ovaries and what role it plays has not yet been described.

Objective: Aimed to investigate ApoC3 expression in ovary of PCOS, and to discuss its potential role in PCOS progression.