Accelerometer-derived movement behaviours and risk of mortality among individuals with pre-existing depression: prospective cohort study.

Background: Evidence is largely limited regarding the extent to which abnormal behavioural profiles, including physical inactivity, sedentary behaviour and inadequate sleep duration, impact long-term health conditions in individuals with pre-existing depression.

Aims: To investigate the associations between accelerometer-derived daily movement behaviours and mortality in individuals with pre-existing depression.

Method: Between 2013 and 2015, a total of 10 914 individuals with pre-existing depression were identified from the UK Biobank through multiple sources including self-reported symptoms, records of antidepressant usage and diagnostic recording based on the 10th Revision of the International Classification of Diseases (ICD-10) codes F32-F33.

Accelerometer-derived 'weekend warrior' physical activity pattern and brain health.

Extensive evidence shows the beneficial effect of adhering to a regular physical activity (PA) pattern on brain health. However, whether the 'weekend warrior' pattern, characterized by concentrated moderate-to-vigorous PA (MVPA) over 1-2 days, is associated with brain health is unclear. Here, we perform a prospective cohort study including 75,629 participants from the UK Biobank with validated accelerometry data.

Association of accelerometer-derived physical activity with all-cause and cause-specific mortality among individuals with cardiovascular diseases: a prospective cohort study.

Aims: To investigate the association of accelerometer-measured intensity-specific physical activity (PA) with all-cause and cause-specific mortality among individuals with cardiovascular disease (CVD).

Methods And Results: In this prospective cohort study, 8024 individuals with pre-existing CVD (mean age: 66.6 years, female: 34.

Associations between device-measured and self-reported physical activity and common mental disorders: Findings from a large-scale prospective cohort study.

Objectives: To investigate the associations between device-measured and self-reported physical activity (PA) and incident common mental disorders in the general population.

Design And Setting: Large-scale prospective cohort study.

Participants: Using the UK Biobank data, a validated PA questionnaire was used to estimate self-reported weekly PA in 365 656 participants between 2006 and 2010 while 91 800 participants wore wrist-worn accelerometers for 7 days in 2013-2015 to derive objectively measured PA.

Accelerometer-derived physical activity and mortality in individuals with type 2 diabetes.

Physical activity (PA) has been shown to reduce diabetes mortality, but largely based on imprecise self-reported data, which may hinder the development of related recommendations. Here, we perform a prospective cohort study of 19,624 individuals with type 2 diabetes (T2D) from the UK Biobank with a median follow-up of 6.9 years.

Trajectories of depressive symptoms and risk of cardiovascular disease, cancer and mortality: a prospective cohort study.

Background: Depressive symptoms are established risk factors for various health outcomes. However, previous studies assessed depressive symptoms at a single time point, neglecting individual variations over time.

Aims: To identify depressive symptoms trajectories through repeated measures and examine their associations with cardiovascular disease (CVD), cancer and mortality.

Healthy lifestyle and the risk of depression recurrence requiring hospitalisation and mortality among adults with pre-existing depression: a prospective cohort study.

Background: Although lifestyle-based treatment approaches are recommended as important aspects of depression care, the quantitative influence of aggregated healthy lifestyles on depression recurrence and mortality remains unknown.

Objective: To investigate the association between healthy lifestyle and the risks of first-time hospitalisation for recurrent depression and mortality.

Methods: 26 164 adults with depression (mean (SD) age, 56.

Physical Activity, Mental Activity, and Risk of Incident Stroke: A Prospective Cohort Study.

Background: Cumulative evidence suggests a correlation between physical or mental activity and the risk of stroke. However, the combined impact of these activities on stroke onset remains unexplored. This study identified physical and mental activity patterns using principal component analysis and investigated their associations with risk of incident stroke in the general population.

Circulating insulin-like growth factor-1 and brain health: Evidence from 369,711 participants in the UK Biobank.

Background: The effects of insulin-like growth factor-1 (IGF-1) deficiency on cognitive decline have been consistently reported in animal studies, but the relationship between IGF-1 and human brain health remains controversial. Our study aimed to investigate the associations of serum IGF-1 concentrations with some brain-related disorders and neuroimaging features.

Methods: This prospective study included 369,711 participants (55.

The association between coffee consumption and risk of incident depression and anxiety: Exploring the benefits of moderate intake.

Accumulating evidence has reported the associations of coffee consumption with physical conditions and mortality, but the associations with mental disorders were limited. The objective of this study was to examine the associations of coffee consumption with incident depression and anxiety, and to assess whether the associations differed by coffee subtypes (instant, ground, and decaffeinated coffee) or additives (milk, sugar-sweetened, and artificial-sweetened). In this prospective cohort study, we utilized data from the UK Biobank and included a total of 146,566 participants who completed the touchscreen questionnaire at baseline between 2006 and 2010.