EViT: An Eagle Vision Transformer With Bi-Fovea Self-Attention.

Owing to advancements in deep learning technology, vision transformers (ViTs) have demonstrated impressive performance in various computer vision tasks. Nonetheless, ViTs still face some challenges, such as high computational complexity and the absence of desirable inductive biases. To alleviate these issues, the potential advantages of combining eagle vision with ViTs are explored.

Helicene-Fused Propellanes: A Geometrically Rigid Multihelicene Nanocarbon with Amplified Chirality.

Here we report the synthesis of a geometrically distinct three-dimensional (3D) chiral nanocarbon, which is composed of three π-extended [6]helicene subunits fused on a [3,3,3]propellane with P,P,M/M,M,P configurations in the helicene subunits. This nanocarbon can isomerize into the thermodynamically more stable isomer with PPP/MMM configurations in the helicene subunits. Both 3D nanocarbons display a very stable configuration, which can be separated by chiral high-performance liquid chromatography (HPLC).

Preparation and Performance Study of Dual-Network Photo-Curable Conductive Silk Fibroin Composite Hydrogel.

The printing precision of hydrogels directly determines the mechanical and electrical performance of scaffolds. In this study, poly(3,4-ethylenedioxythiophene)-poly (styrenesulfonate) (PEDOT:PSS) was directly compounded with glycidyl methacrylate-modified silk fibroin (Sil-MA) through a one-pot method to increase the solid content of the printing ink, enhancing its mechanical, electrical, and printability properties. A dual-network photo-curable conductive silk fibroin composite hydrogel (CDMA) was successfully prepared.

Epoxy Vitrimer with Excellent Mechanical Properties and High for Detachable Structural Adhesives.

It is a long-standing challenge for thermoset resins to simultaneously achieve outstanding thermomechanical and mechanical properties as well as rapid network reconfiguration due to the trade-off between chemical bond transformation and stability of the network. The design of the vitrimer network topology is an effective strategy to address the above issues. Here, we prepared an epoxy vitrimer material (DGEBA-API-MHHPA) with excellent mechanical properties and high glass-transition temperature () by introducing rigid-flexible integrated side chains [1-(3-aminopropyl) imidazole (API)], which endow DGEBA-API-MHHPA multiple interactions including "internal antiplasticization" effect, intermolecular hydrogen bonds, and π-π interactions.

Spatiotemporal changes of vegetation in the northern foothills of Qinling Mountains based on kNDVI considering climate time-lag effects and human activities.

Vegetation is fundamental to regulating the climate system and ensuring carbon balance. Recognizing the effects of climate change (CC) and human activities (HA) is vital for understanding shifts in vegetation. However, climate time-lag effects are rarely measured, resulting in an inadequate assessment of CC's effects on vegetation dynamics.

Manipulation of ion/electron carrier genes in the model diatom enables its growth under lethal acidic stress.

A major obstacle to exploiting industrial flue gas for microalgae cultivation is the unfavorable acidic environment. We previously identified three upregulated genes in the low-pH-adapted model diatom : ferredoxin (PtFDX), cation/proton antiporter (PtCPA), and HCO transporter (PtSCL4-2). Here, we individually overexpressed these genes in to investigate their respective roles in resisting acidic stress (pH 5.

Evolutionary analysis of CBFs/DREB1s in temperate and tropical woody bamboos and functional study of PeDREB1A3 under cold and drought stress.

Bamboo forests are vulnerable to extreme cold, as well as drought caused by declining rainfall or persistent hot, under global climate change. The C-repeat binding factors/dehydration-responsive element binding protein 1s (CBFs/DREB1s) are vital to acquiring tolerance to deal with the changing climate in plants. Herein, we investigated the evolution of CBFs/DREB1s in four temperate or tropical woody bamboos.

Exploring the natural-socioeconomic driving and response mechanisms of ecosystem services interactions to optimize ecosystem management: A case study in the Yarlung Zangbo River Basin.

Revealing the complex interactions between ecosystem services (ESs) and their underlying mechanisms is a prerequisite for formulating sustainable ecological management strategies. However, few studies have conducted a comprehensive analysis of the driving and response mechanisms of ESs interactions. Therefore, this study established an integrated framework to first quantify the interactions between ESs, then identify their dominant natural-socioeconomic drivers, explore their spatial non-stationary responses, and ultimately propose corresponding strategies to optimize ecosystem management.

Aldehyde Directed In Situ Loading of Ag Nanodots Around the Open Metal Sites of MOFs for the Tandem Catalysis of Nitrate to Ammonia.

Both spatial arrangement and intrinsic activity of electrocatalysts with dual-active sites are widely designed to match the coupling reaction between nitrate and water, in which most of the reactive intermediates can be optimized to achieve a high yield rate of ammonia. Herein, by introducing the aldehyde group inside metal-organic frameworks (MOFs) in advance, an aldehyde-induced method is achieved to direct the in situ nucleation of Ag nanodots depending on the mesopores of MOFs via a simple silver mirror reaction. The key point here is that the spatial arrangement between the aldehyde group and open metal sites is fixed end to end, which makes the aldehyde group a built-in redox-active site to drive the in situ nucleation of Ag nanodots next to the open metal sites of MOFs.

Systematic conservation planning considering ecosystem services can optimize the conservation system in the Qinling-Daba Mountains.

Protected area are the cornerstone of biodiversity and ecosystem service conservation at the local, regional, and global levels. In 2019, China proposed the establishment of a nature reserve system (NRS)centered on national parks, integrating and improving various existing protected areas. This study focuses on the Qinling‒Daba Mountains, an area crucial for both biodiversity and ecosystem services.

Zinc transporter 1 functions in copper uptake and cuproptosis.

Copper (Cu) is a co-factor for several essential metabolic enzymes. Disruption of Cu homeostasis results in genetic diseases such as Wilson's disease. Here, we show that the zinc transporter 1 (ZnT1), known to export zinc (Zn) out of the cell, also mediates Cu entry into cells and is required for Cu-induced cell death, cuproptosis.

In silico discovery and anti-tumor bioactivities validation of an algal lectin from Kappaphycus alvarezii genome.

Lectins are proteins that bind specifically and reversibly to carbohydrates, and some of them have significant anti-tumor activities. Compared to those of lectins from land plants, there are far fewer studies on algal lectins, despite of the high biodiversity of algae. However, canonical strategies based on chromatographic feature-oriented screening cannot satisfy the requirement for algal lectin discovery.

Bridging Nickel-MOF and Copper Single Atoms/Clusters with H-Substituted Graphdiyne for the Tandem Catalysis of Nitrate to Ammonia.

Interfacial engineering of synergistic catalysts is one of the keys to achieving multiple proton-coupled electron transfer processes in nitrate-to-ammonia conversion. Herein, by joining ultrathin nickel-based metal-organic framework (denoted Ni-MOF) nanosheets with few-layered hydrogen-substituted graphdiyne-supported copper single atoms and clusters (denoted HsGDY@Cu), a tandem catalyst of Ni-MOFs@HsGDY@Cu with dual-active interfaces was developed for the concerted catalysis of nitrate-to-ammonia. In such a system, the sandwiched HsGDY layer could serve as a bridge to connect the coordinated unsaturated Ni sites with Cu single atoms/clusters in a limited range of 0 to 3.

Ecological barriers: An approach to ecological conservation and restoration in China.

The Chinese government has pursued comprehensive ecological conservation and restoration by establishing an ecological barrier system. However, the majority of international research tends to focus on the connectivity between habitats, overlooking the functions that ecological barriers play in ecological conservation and restoration. The existing literature lacks a systematic exploration of the theory and practice of ecological barriers.

The unfolded protein response pathway as a possible link in the pathogenesis of COVID-19 and sepsis.

The global impact of the COVID-19 pandemic has been substantial. Emerging evidence underscores a strong clinical connection between COVID-19 and sepsis. Numerous studies have identified the unfolded protein response (UPR) pathway as a crucial pathogenic pathway for both COVID-19 and sepsis, but it remains to be investigated whether this signaling pathway operates as a common pathogenic mechanism for both COVID-19 and sepsis.

Hybrid nanoarrays of Cu-MOFs@H-substituted graphdiyne with various levels of Lewis acidity for nitrate electroreduction.

To mimic enzymes in nature, a set of hybrid nanoarrays of Cu-MOFs sealed in hydrogen-substituted graphdiyne has been developed in order to serve as Lewis-acid-promoted catalysts. By regulating the electron-withdrawing capability of the ligands bridging Cu sites, these Cu-MOFs provided different levels of Lewis acidity toward nitrate affinity, a feature crucial for nitrate-to-ammonia conversion.

Interfacial Engineering of Bimetallic Ni/Co-MOFs with H-Substituted Graphdiyne for Ammonia Electrosynthesis from Nitrate.

The electrochemical synthesis of ammonia is highly dependent on the coupling reaction between nitrate and water, for which an electrocatalyst with a multifunctional interface is anticipated to promote the deoxygenation and hydrogenation of nitrate with water. Herein, by engineering the surface of bimetallic Ni/Co-MOFs (NiCoBDC) with hydrogen-substituted graphdiyne (HsGDY), a hybrid nanoarray of NiCoBDC@HsGDY with a multifunctional interface has been achieved toward scale-up of the nitrate-to-ammonia conversion. On the one hand, a partial electron transfers from Ni to the coordinatively unsaturated Co on the surface of NiCoBDC, which not only promotes the deoxygenation of *NO on Co but also activates the water-dissociation to *H on Ni.

A systematic and comprehensive analysis of T cell exhaustion related to therapy in lung adenocarcinoma tumor microenvironment.

: T cell exhaustion (TEX) is an important immune escape mechanism, and an in-depth understanding of it can help improve cancer immunotherapy. However, the prognostic role of TEX in malignant lung adenocarcinoma (LUAD) remains unclear. : Through TCGA and GEO datasets, we enrolled a total of 498 LUAD patients.

ER stress-related mRNA-lncRNA co-expression gene signature predicts the prognosis and immune implications of esophageal cancer.

Background: Esophageal cancer (EC) is one of the most common malignant cancers in the world. Endoplasmic reticulum (ER) stress is an adaptive response to various stress conditions and has been implicated in the development of various types of cancer. Long noncoding RNAs (lncRNAs) refer to a group of noncoding RNAs (ncRNAs), which regulate gene expression by interacting with DNA, RNA and proteins.

System analysis based on the ER stress-related genes identifies WFS1 as a novel therapy target for colon cancer.

Background: Colon cancer (COAD) is the third-largest common malignant tumor and the fourth major cause of cancer death in the world. Endoplasmic reticulum (ER) stress has a great influence on cell growth, migration, proliferation, invasion, angiogenesis, and chemoresistance of massive tumors. Although ER stress is known to play an important role in various types of cancer, the prognostic model based on ER stress-related genes (ERSRGs) in colon cancer has not been constructed yet.

System analysis based on the cuproptosis-related genes identifies LIPT1 as a novel therapy target for liver hepatocellular carcinoma.

Background: Liver hepatocellular carcinoma (LIHC) ranks sixth among the most common types of cancer with a high mortality rate. Cuproptosis is a newly discovered type of cell death in tumor, which is characterized by accumulation of intracellular copper leading to the aggregation of mitochondrial lipoproteins and destabilization of proteins. Thus, understanding the exact effects of cuproptosis-related genes in LIHC and determining their prognosticvalue is critical.

Polymer Encapsulation Strategy toward 3D Printable, Sustainable, and Reliable Form-Stable Phase Change Materials for Advanced Thermal Energy Storage.

Form-stable phase change materials (PCMs) have garnered tremendous attention in thermal energy storage (TES) owing to their remarkable latent heat. However, the integration of intelligent manufacturing, recycling, and optimized multifunction is considered not feasible for form-stable PCMs due to the restriction of encapsulation technology. Here, an excellent polymer encapsulation strategy is proposed to prepare 3D printable, sustainable, and reliable form-stable PCMs (Si), which are universal for petroleum-based and biobased long alkyl compounds.

Robust, Multiresponsive, Superhydrophobic, and Oleophobic Nanocomposites via a Highly Efficient Multifluorination Strategy.

Artificial superhydrophobic surfaces are garnering constant attention due to their wide applications. However, it is a great challenge for superhydrophobic materials to simultaneously achieve good oil repellency, mechanochemical robustness, adhesion, thermomechanical properties, and multiresponsive ability. Herein, we propose a highly efficient multifluorination strategy to prepare superhydrophobic nanocomposites with the above features, which can be used as monoliths or coatings on various substrates.