Publications by authors named "Jiageng Guo"

Cinnamon oil, an essential oil extracted from plants of the genus Cinnamomum, has been highly valued in ancient Chinese texts for its medicinal properties. This review summarizes the chemical composition, pharmacological actions, and various applications of cinnamon oil, highlighting its potential in medical and industrial fields. By systematically searching and evaluating studies from major scientific databases including Web of Science, PubMed, and ScienceDirect, we provide a comprehensive analysis of the therapeutic potential of cinnamon oil.

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The skin barrier is essential for maintaining the body's internal homeostasis, protecting against harmful external substances, and regulating water and electrolyte balance. Traditional Chinese Medicine (TCM) offers notable advantages in restoring skin barrier function due to its diverse components, targets, and pathways. Recent studies have demonstrated that active ingredients in TCM can safely and effectively repair damaged skin barriers, reinstating their proper functions.

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The PI3K/AKT/GSK-3β signaling pathway plays a pivotal role in numerous physiological and pathological processes, including cell proliferation, apoptosis, differentiation, and metabolic regulation. Aberrant activation of the PI3K/AKT pathway is intricately linked to development of tumor. GSK-3β, belonging to the serine/threonine protein kinase family, is crucial in the pathogenesis of liver cancer.

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Article Synopsis
  • * This review compiles extensive research, highlighting cinnamaldehyde's role in treating inflammatory diseases, infections, cancer, diabetes, and cardiovascular issues by inhibiting the NF-κB pathway and managing pro-inflammatory responses.
  • * There is promising evidence from both preclinical and clinical studies supporting cinnamaldehyde’s potential benefits, but further research is needed to fully understand its mechanisms and ensure safety for developing new therapeutic drugs.
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