Publications by authors named "Jiade Yu"
Scalp contact dermatitis (SCD) represents a less common manifestation of contact dermatitis and is susceptible to misdiagnosis due to its atypical clinical presentations, including hair thinning, eczematous lesions, and scalp pruritus. Notably, personal care products are recognized as common etiologies in the development of SCD. Synthetic hair extensions, with prevalent use in individuals of color, are also known to cause contact dermatitis, due to allergenic components such as acrylates and disperse dyes.
View Article and Find Full Text PDFThe American Contact Dermatitis Society (ACDS) selected sulfites as the 2024 Allergen of the Year. These common and potentially allergenic ingredients are used as preservatives and antioxidants in a variety of foods, beverages, medications, and personal care products. In this article, we review common sources of sulfite exposure, clinical manifestations of allergic contact dermatitis (ACD) to sulfites, and patch testing considerations for this emerging allergen.
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- - Eyelid dermatitis is a prevalent skin condition characterized by inflammation, with allergic contact dermatitis (ACD) being the most common cause, triggered by exposure to allergens.
- - Common allergens linked to eyelid dermatitis include metals, fragrances, preservatives, and certain medications found in cosmetics and everyday products.
- - Effective treatment focuses on avoiding allergens and includes patient education on recognizing triggers; the review also covers signs, evaluation methods, and patch testing for diagnosis.
Article Synopsis
- - Allergic contact dermatitis (ACD) can result from allergens found in personal care and cosmetic products, particularly in depilatory waxing items used at salons and available online.
- - The study analyzed ingredients from salon products and top online wax products, identifying common allergens like vitamin E, colophony, and botanicals, which were present at varying rates among the products examined.
- - Recognizing these allergens is important for ensuring safety during hair removal procedures, as they may cause reactions, even if they don’t frequently result in ACD.
Article Synopsis
- Fragrances are prevalent in many everyday products, including perfumes and air fresheners, and can also be found in unexpected sources like workplaces, often hidden even in "fragrance free" items.
- Allergic contact dermatitis (ACD) caused by fragrances is a common issue, emphasizing the need for both patients and healthcare providers to be informed about it for effective management.
- This review highlights the chemistry and prevalence of fragrance-related ACD, provides guidance on patch testing, and stresses the importance of educating patients on avoiding triggers to improve treatment success.
Atopic dermatitis (AD) and allergic contact dermatitis (ACD) are common inflammatory skin diseases in both children and adults that present similarly and often coexist. Patch testing is the gold standard for establishing the diagnosis of ACD and can often help distinct between the 2 conditions. Patch testing is more challenging in patients with underlying AD due to potential for angry back reactions.
View Article and Find Full Text PDFBackground: Janus kinase inhibitors (JAKi) have the potential to alter the landscape of atopic dermatitis (AD) management dramatically, owing to promising efficacy results from phase III trials and their rapid onset of action. However, JAKi are not without risk, and their use is not appropriate for all patients with AD, making this a medication class that dermatologists should understand and consider when treating patients with moderate-to-severe AD.
Objectives: To provide a consensus expert opinion statement from the International Eczema Council (IEC) that provides a pragmatic approach to prescribing JAKi, including choosing appropriate patients and dosing, clinical and laboratory monitoring and advice about long-term use.
Comorbid Scenarios in Contact Dermatitis: Atopic Dermatitis, Irritant Dermatitis, and Extremes of Age.
J Allergy Clin Immunol Pract
September 2024
Article Synopsis
- - Contact dermatitis can be allergic (caused by a T cell response to haptens) or irritant (a toxic reaction), making diagnosis challenging.
- - Patch testing is the main method for identifying allergic contact dermatitis, but accurate interpretation requires a skilled clinician to consider both test results and patient history.
- - Unique challenges arise in diagnosing allergic contact dermatitis in patients with conditions like atopic dermatitis, especially in very young or old patients, where immune systems and testing space vary.
Article Synopsis
- - The study analyzed contact allergies to peppermint (MP) oil using data from the North American Contact Dermatitis Group, finding that out of 28,128 patients tested, only 161 (0.6%) exhibited an allergic reaction.
- - The majority of allergic patients were female (77%) and over 40 years old (71.4%), with common dermatitis locations being the face (31.7%), hands (17.4%), and generalized areas (18.6%).
- - A significant number (30.4%) experienced strong to extreme reactions, primarily linked to products like oral hygiene items, foods, and lip products; many also had co-reactions with other fragrance allergens, indicating that around 40% of cases
Article Synopsis
- Photoallergic contact dermatitis (PACD) is a hypersensitivity reaction triggered by allergens only when exposed to UV light, requiring photopatch testing (PhotoPT) for diagnosis.* -
- A study from 2009-2020 involving 454 patients revealed that most were women, aged 21-60, and the majority were White; results showed 119 positive tests, predominantly related to sunscreen agents like benzophenones.* -
- Among the diagnosed conditions, approximately 17.2% of patients had PACD, while other diagnoses included allergic contact dermatitis, polymorphous light eruption, and chronic actinic dermatitis, highlighting the need for photopatch testing in these cases.*
Construction workers (CWs) are at risk for occupational contact dermatitis (CD) owing to workplace exposures. Determine the prevalence of occupational allergic CD and characterize common occupational allergens in CWs referred for patch testing in the United States and Canada. Retrospective cross-sectional analysis of patients patch tested by the North American Contact Dermatitis Group from 2001 to 2020.
View Article and Find Full Text PDFFrontal fibrosing alopecia (FFA) is an increasingly common diagnosis, especially in middle-aged women, and has garnered growing attention in the scientific literature. This variant of lichen planopilaris (LPP) is recognized as a progressive scarring alopecia affecting the frontal and temporal regions of the scalp as well as the eyebrows and occasionally other sites. Although its precise etiology remains elusive, various factors such as genetics, medications, hormonal influences, and environmental exposures-including specific chemicals present in sunscreens-have been implicated in its pathogenesis but without evidence of causality.
View Article and Find Full Text PDFPatch testing outcomes in children at the Massachusetts General Hospital.
J Am Acad Dermatol
August 2024
Doubtful patch test reactions generally do not meet criterion for positivity in patch testing. However, the North American Contact Dermatitis Group (NACDG) allows for doubtful reactions to be coded with a final determination of "allergic/positive" based on the temporal pattern, appearance, known characteristics of the allergen, and/or other supportive patch test reactions. To analyze NACDG data from the 2019-2020 patch test cycle to identify patterns in the interpretation and relevance of doubtful reactions.
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