Publications by authors named "Jiachong Qiu"
Front Genet
November 2022
Article Synopsis
- N-methyladenosine (m6A) is a common RNA modification linked to various cardiovascular diseases, and while studies suggest its involvement in abdominal aortic aneurysm (AAA), the complete range of m6A regulators remains unclear.
- By analyzing mRNA levels of 17 m6A regulators, researchers identified three m6A methylation subtypes in AAA patients, distinguishing between more immunologically activated clusters and those associated with extracellular matrix stability.
- The study developed an m6Ascore model to assess m6A methylation patterns, finding that a high m6Ascore correlates with increased inflammatory activity in AAA, potentially guiding personalized treatment strategies in the future.
