Aims: Management of blood glucose fluctuation is essential for diabetes. Exercise is a key therapeutic strategy for diabetes patients, although little is known about determinants of glycemic response to exercise training. We aimed to investigate the effect of combined aerobic and resistance exercise training on blood glucose fluctuation in type 2 diabetes patients and explore the predictors of exercise-induced glycemic response.
View Article and Find Full Text PDFIntroduction: Obesity is a complex and multifactorial disease that has affected many adolescents in recent decades. Clinical practice guidelines recommend exercise as the key treatment option for adolescents with overweight and obesity. However, the effects of virtual reality (VR) exercise on the physical and brain health of adolescents with overweight and obese remain unclear.
View Article and Find Full Text PDFSensors (Basel)
October 2022
Lq (0 < q ≤ 1) regularization has been confirmed effective when applied to sparse SAR imaging. However, the inaccuracies caused by motion errors in the observation model will lead to various degradations and defocus in the reconstructed image. For high-resolution and light-small SAR systems, the range-variant motion errors will decrease the accuracy of range cell migration correction (RCMC), and residual range cell migration (RCM) will exceed multiple range resolution cells and degrade the image quality substantially.
View Article and Find Full Text PDFInt J Biol Macromol
December 2022
Recently, efficient synthesis of furan-based chemicals from biomacromolecule via chemoenzymatic approaches have been widely recognized. In this work, an efficient conversion of biomacromolecule (e.g.
View Article and Find Full Text PDF5-Hydroxymethyl-2-furfurylamine (5-HMFA) as an important 5-HMF derivative has been widely utilized in the manufacture of diuretics, antihypertensive drugs, preservatives and curing agents. In this work, an efficient chemoenzymatic route was constructed for producing 5-(hydroxymethyl)furfurylamine (5-HMFA) from biobased -fructose in deep eutectic solvent Betaine:Glycerol-water. The introduction of Betaine:Glycerol could greatly promote the dehydration of -fructose to 5-HMF and inhibit the secondary decomposition reactions of 5-HMF, compared with a single aqueous phase.
View Article and Find Full Text PDFDuring adaptive radiation, mitochondria have co-evolved with their hosts, leading to gain or loss of subunits and assembly factors of respiratory complexes. Plant mitochondrial complex I harbors ∼40 nuclear- and 9 mitochondrial-encoded subunits, and is formed by stepwise assembly during which different intermediates are integrated via various assembly factors. In mammals, the mitochondrial complex I intermediate assembly (MCIA) complex is required for building the membrane arm module.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
February 2022
The gut microbiota is a newly identified contributor to the development of non-alcoholic fatty liver disease (NAFLD). Previous studies of (), a species of that is common in the human intestinal tract, have demonstrated that it can alleviate liver steatosis and steatohepatitis. Fibroblast growth factor 21 (FGF21) has long been considered as a biomarker of NAFLD, and recent studies have shown the protective effect of FGF21 analogs on NAFLD.
View Article and Find Full Text PDFChemoenzymatic cascade catalysis using deep eutectic solvent-silica heterogeneous catalyst and reductase biocatalyst was constructed for synthesizing furfuryl alcohol from biomass in one-pot manner. A novel heterogeneous catalyst B:LA-SG(SiO) was firstly prepared by immobilizing deep eutectic solvent Betaine:Lactic acid on silica with sol-gel method using tetraethyl orthosilicate as silicon source. High furfural yield (45.
View Article and Find Full Text PDFBioresour Bioprocess
November 2021
Heterogeneous tin-based sulfonated graphite (Sn-GP) catalyst was prepared with graphite as carrier. The physicochemical properties of Sn-GP were captured by FT-IR, XRD, SEM and BET. Organic acids with different pKa values were used to assist Sn-GP for transforming corncob (CC), and a linear equation (Furfural yield = - 7.
View Article and Find Full Text PDFBackground: The fibroblast growth factor (FGF) 21-adiponectin pathway is involved in the regulation of insulin resistance. However, the relationship between the FGF21-adiponectin pathway and type 2 diabetes in humans is unclear. Here, we investigated the association of FGF21/adiponectin ratio with deterioration in glycemia in a prospective cohort study.
View Article and Find Full Text PDFAlthough obesity occurs in most of the patients with type 2 diabetes (T2D), a fraction of patients with T2D are underweight or have normal weight. Several studies have linked the gut microbiome to obesity and T2D, but the role of gut microbiota in lean individuals with T2D having unique clinical characteristics remains unclear. A metagenomic and targeted metabolomic analysis is conducted in 182 lean and abdominally obese individuals with and without newly diagnosed T2D.
View Article and Find Full Text PDFThe information on core components in maize polycomb repressive complex 2 (PRC2) are updated at a genome-wide scale, and the protein-protein interaction networks of PRC2 components are further provided in maize. The evolutionarily conserved polycomb group (PcG) proteins form multi-subunits polycomb repressive complexes (PRCs) that repress gene expression via chromatin condensation. In Arabidopsis, three distinct PRC2s have been identified, each determining a specific developmental program with partly functional redundancy.
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