Publications by authors named "Jiachao Pan"
Article Synopsis
- Immune checkpoint inhibitors are medicines that help treat advanced lung cancer but can cause side effects in some patients, making them more likely to get infections.
- A 56-year-old man with lung cancer got treatment but later faced serious kidney problems and pneumonia caused by a rare infection called PJP after taking high doses of steroids.
- The patient improved after being treated for the infections, but the doctors suggested careful monitoring for PJP in patients who receive these cancer treatments, especially after radiation therapy.
Background & Aims: AIM2 plays an important role in innate immunity, but its role in regulating the immune response to hepatitis B virus (HBV) is unknown. We hypothesized that AIM2 expression is positively correlated with HBV-mediated inflammation in patients with HBV-associated glomerulonephritis (HBV-GN), potentiating inflammation and leading to renal damage. We therefore analyzed the expression of AIM2 and inflammatory factors in HBV-GN tissues and cell lines relative to the inflammatory response to HBV infection and HBV status.
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