Publications by authors named "Jiabo Chen"

Article Synopsis
  • Cuproptosis is a newly discovered form of programmed cell death influenced by copper, and this research aims to investigate its relationship with Wilms tumor (WT) and related genes, ultimately creating a predictive model for WT.
  • Researchers analyzed four gene expression datasets from the GEO database to assess the expression of Cuproptosis-related genes (CRGs), uncover clusters of WT, and examine immune cell infiltration patterns in WT samples.
  • The study identified 13 significant CRGs associated with WT, discovered differences in immune cell presence compared to normal tissue, and determined that a support vector machine (SVM) model performed best in predicting WT risk using five specific genes, with validation through calibration and decision curve analyses.
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Waterlogging stress causes substantial destruction to plant growth and production under climatic fluctuations globally. Plants hormones have been widely explored in numerous crops, displaying an imperative role in crop defense and growth mechanism. However, there is a paucity of research on the subject of plant hormones regulating waterlogging stress responses in wheat crop.

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  • Artemisia argyi is a medicinal plant known for its health benefits due to its various triterpenoids that have anti-viral, anti-cancer, and anti-oxidant properties.
  • The study focuses on isolating and identifying four genes related to the 2,3-oxidosqualene cyclase (OSC) family, which are crucial for the triterpenoid biosynthesis pathway in A. argyi.
  • Three of the isolated OSC genes were shown to produce different triterpenoids through a yeast expression system, enhancing knowledge of how these valuable compounds are synthesized in the plant.
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  • This study analyzes carbon emissions (CE) from 247 wastewater treatment plants (WWTPs) in China to assess the effectiveness of new pollution control regulations and identify factors influencing emissions.
  • The average CE intensity was found to be 0.45 kgCO-eq/m, with variations based on region, season, water quality, treatment methods, and facility types, specifically noting that underground WWTPs had higher emissions than aboveground ones.
  • The findings highlight the potential for emission reductions and offer a scientific foundation for developing targeted strategies to improve CE management in wastewater treatment processes.
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Purpose: This study aimed to analyze the expression and prognosis of SRY-box transcription factor 11 (SOX11) in neuroblastoma (NB), as well as the biological function and potential regulatory mechanism of SOX11 in NB.

Methods: Public RNA sequencing was used to detect the expression level of SOX11. The Kaplan-Meier curve and hazard ratios (HR) were used to determine the prognostic value of SOX11 in NB.

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Ultrasound and ultraviolet light have good inactivation performance against pathogens in sewage. In this study, the inactivation mechanisms of 60 kHz ultrasound and ultraviolet radiation against Staphylococcus aureus (S. aureus) were studied from the perspectives of cell phenotype and transcriptome for the first time.

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In order to facilitate the observation in the process of secondary equipment operation and maintenance supervision and the detection and tracking of operation and maintenance personnel, a secondary operation and maintenance supervision system based on AR modeling and indoor positioning is designed. The whole system is divided into seven levels and a unified information base, in which the basic level contains all kinds of secondary equipment; AR modeling layer uses augmented reality technology to create models for each secondary equipment in the basic layer, and determines the equipment position information based on ranging positioning technology; The data acquisition layer collects all kinds of original management data based on the constructed secondary equipment model; The data analysis layer reads and analyzes the information of the data acquisition layer through the data bus; The process support layer provides task scheduling support for the integrated management application based on the data analysis results; The integrated application layer uniformly monitors the secondary equipment based on the task scheduling results; The presentation layer is responsible for the interface presentation of all operation and maintenance and security management information of the system, and the unified information base provides data support for the whole system. The experimental results show that the secondary equipment model in the designed system has high definition, can obtain more image details, can realize the 3D display and real-time interaction of the secondary equipment operation and maintenance supervision results, and accurately mark the target and track for the staff.

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This study explored the inactivation of Staphylococcus aureus (S. aureus) by ultrasound (US) and peracetic acid (PAA) coupling with UV simultaneously (US/PAA/UV) or sequentially (US→PAA/UV) for the strengthened disinfection. The result showed that US→PAA/UV system had excellent inactivation performance with 5.

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Poly(vinyl alcohol) (PVA)/modified porous starch (MPS) gel beads were prepared through chemical cross-linking by incorporating with MPS, which was obtained by modifying porous starch (PS) with polyethyleneimine (PEI) and glutaraldehyde (GA). Addition of MPS could improve the storage modulus and the effective crosslinking density () of the gel beads, and the mechanical properties were enhanced. The PVA-MPS gel beads were preserved as immobilized microbial carriers for 40 d and reactivated in wastewater.

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Background: Laparoscopic splenectomy (LS), a treatment for both benign and malignant splenic diseases, can prove technically challenging in patients with massive splenomegaly. In particular, the optimal surgical modality for treating massive splenomegaly in children remains controversial.

Methods: The clinicopathologic data of 289 pediatric patients undergoing splenectomy for massive splenomegaly were studied in a retrospective analysis.

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In wastewater treatment plants (WWTPs), aeration is vital for microbial oxygen needs. To achieve carbon neutrality, optimizing aeration for energy and emissions reduction is imperative. Machine learning (ML) is used in wastewater treatment to reveal complex rules in large data sets has become a trend.

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Lanthanide-doped metal-organic frameworks (Ln-MOFs) have versatile luminescence properties, however it is challenging to achieve lanthanide-based upconversion luminescence in these materials. Here, 1,3,5-benzenetricarboxylic acid (BTC) and trivalent Yb ions were used to generate crystalline Yb-BTC MOF 1D-microrods with upconversion luminescence under near infrared excitation via cooperative luminescence. Subsequently, the Yb-BTC MOFs were doped with a variety of different lanthanides to evaluate the potential for Yb -based upconversion and energy transfer.

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In-depth knowledge of the deterioration and reactivation of the anaerobic ammonium oxidation (anammox) induced by carbon-to-nitrogen (C/N) is still lacking. Herein, the anammox performance was investigated in an anaerobic sequence biofilm batch reactor fed with low-strength partial nitration effluent in the range of C/N ratio from 0.5 to 3.

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Genistein (Gen), a kind of natural isoflavone drug monomer with poor water solubility and low oral absorption, was incorporated into oral nanoparticles with a new mesoporous carrier material, NH-MCM-41, which was synthesized by copolycondensation. When the ratio of Gen to NH-MCM-41 was 1:0.5, the maximum adsorption capacity of Gen was 13.

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Background: Hirschsprung's disease (HD) is a commonly digestive malformation in children that usually requires surgery. This study aims to evaluate the short-term efficacy of conventional laparoscopic surgery (CLS), transumbilical single-hole laparoscopic surgery (TU-LESS), and robotic surgery (RS) in the treatment of Hirschsprung's disease.

Methods: 90 patients with Hirschsprung's disease undergone laparoscopic surgery at our center between 2015 and 2019, divided into three groups (group CLS, TU-LESS and RS), were retrospectively analysed.

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is an important economic plant that is rich in lipophilic triterpenols with pharmacological activities including antiallergic, anti-inflammatory, and anticancer activities. However, the key enzymes related to triterpene biosynthesis have seldom been studied in . Oxidosqualene cyclases (OSCs) are the rate-limiting enzymes related to triterpene biosynthesis.

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One-stage anammox-based autotrophic nitrogen removal technology has attracted increasing interest to sustainable biological nitrogen removal for future wastewater treatment. However, its application in mainstream municipal wastewater treatment is still challenging due to low nitrogen and high organics of raw wastewater. Herein, a novel Simultaneous Carbon Oxidation, partial Comammox, Denitratation and Anammox (SCOCDA) was firstly developed in a single sequencing batch biofilm reactor operated at a dissolved oxygen concentration of ∼0.

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There are many reports on the application of minimally invasive technology in correction of children's vesicoureteral junction obstruction (VUJO), but there is no report on the treatment of children's VUJO with the transumbilical laparoendoscopic single-site surgery (TU-LESS) Lich-Gregoir method. We aimed to comparatively analyze the therapeutic outcomes of transvesicoscopic ureteral reimplantation Cohen (TUR-C) procedure and TU-LESS Lich-Gregoir (TU-LESS-LG) procedure in pediatric VUJO. The data of 49 children with VUJO, admitted from January 2016 to January 2020, were retrospectively analyzed.

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is an immensely popular medicinal herb in China, which contains an abundant of mangiferin. As an important bioactive xanthone -glycoside, mangiferin possesses a variety of pharmacological activities and is derived from the cyclization reaction of a benzophenone -glycoside (maclurin). Biosynthetically, -glycosyltransferases are critical for the formation of benzophenone -glycosides.

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Purpose: The molecular mechanisms and signal pathways of ferroptosis in hepatoblastoma (HB) have not yet been clarified. In previous studies, activating transcription factor 3 (ATF3) was reported to be correlated with several tumors, but the clinical significance of ATF3 has never been determined. Herein, we investigated the clinicopathological value and mechanisms of ATF3 in regulating ferroptosis in HB.

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Rotavirus (RV) is one of the main pathogens that induce infantile diarrhea and by now no effective drugs are available for RV-induced infantile diarrhea. Thus the development of novel models is of vital importance for the pathological research of RV-induced infantile diarrhea, as well as the progress of the associated treatment strategy. Here we introduced for the first time that RV-Wa strain and RV-SA-11 strain could infect 5 dpf(day post fertilization) and 28 dpf larvae, to induce infantile diarrhea model that was highly consistent with the clinical infection of infants.

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Photothermal therapy has been considered a powerful means of cancer therapy due to its minimal invasiveness, effectiveness, and convenience. Although promising, the therapeutic effects are greatly limited as they rely on the photothermal agent (PTA). It is urgent to develop new PTAs with high photothermal conversion performance, especially under irradiation in the long-wavelength biowindows.

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Carbon monoxide (CO) can cause mitochondrial dysfunction, inducing apoptosis of cancer cells, which sheds light on a potential alternative for cancer treatment. However, the existing CO-based compounds are inherently limited by their chemical nature, such as high biological toxicity and uncontrolled CO release. Therefore, a nanoplatform - UmPF - that addresses such pain points is urgently in demand.

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