Subtyping colorectal cancer based on septic shock-associated genes: prognosis and immune characteristics.

Background: Sepsis and colorectal cancer (CRC) are leading causes of death. Given their mutual dependence for susceptibility, we used bioinformatics to explore potential connections between septic shock (SS) and CRC.

Methods: We identified 452 co-expressed genes between SS-related differential expression genes (SS-DEGs) and CRC patient-expressed genes (TCGA-CRC genes).

Intermolecular Non-Bonded Interactions from Machine Learning Datasets.

Accurate determination of intermolecular non-covalent-bonded or non-bonded interactions is the key to potentially useful molecular dynamics simulations of polymer systems. However, it is challenging to balance both the accuracy and computational cost in force field modelling. One of the main difficulties is properly representing the calculated energy data as a continuous force function.

Fast testing of partial camera lenses based on a liquid crystal spatial light modulator.

Today, there are strict requirements for the quality inspection of mobile phone cameras, as the design tolerance is getting critically tighter. In order to avoid unnecessary disposal of lens components when testing and assembling the complete cameras, testing the quality of each single lens group in advance before the final assembly is effective. However, as part of a whole camera, a single lens group cannot generate a sharp image independently; it needs to be combined with other elements in the testing system and assembled precisely.

A large scale screen for genes (3rd chromosome) related to Wingless signaling pathway.

A wing specific F1 genetic screen was carried out using the powerful Drosophila genetic system, combined with yeast FRT/FLP and GAL4/UAS system. Form the wing phenotypes and germline clone embryonic cuticle phenotypes observed in these mutant alleles, a number of mutant alleles of known or unknown genes were isolated. Among them, fifteen mutant alleles related to Wingless signal transduction were further isolated; the arm of these mutations located were determined, and their location in the chromosome were roughly mapped.