Publications by Jia-zeng Xia

Publications by authors named "Jia-zeng Xia"

Front Cell Dev Biol

June 2024

Long non-coding RNAs (lncRNAs) are over 200 nucleotides long and have been found to play a significant role in cancer by influencing processes like cell death, growth, and the spread of cancer cells.
Research has shown that autophagy, the body's way of removing damaged cells and proteins, can have both protective and harmful effects in cancer scenarios, particularly when lncRNA expression is not regulated properly.
The manuscript emphasizes the need to understand how lncRNAs interact with autophagy, as this relationship could have important implications for cancer treatment and research.

Future Oncol

December 2022

Researchers are studying treatment options for gastric cancer patients with para-aortic lymph node (PAN) metastasis, which is usually considered inoperable; they're focusing on cases limited to specific lymph node regions No.16a2/b1.
The treatment plan involves a combination of preoperative therapy (nab-paclitaxel, oxaliplatin, and S-1), followed by D2 gastrectomy with PAN dissection, and then additional postoperative therapies.
The study aims to evaluate the effectiveness of this approach through various measures, including overall survival rates, disease-free survival, and the frequency of complications.

Zhonghua Wei Chang Wai Ke Za Zhi

February 2011

The study examines the DNA methylation of the hsa-miR-124a gene in human gastric cancer tissues and its relationship with Rb and CDK6 protein expression and various clinical factors.
The researchers used methylation-specific PCR to assess DNA methylation in samples from 30 patients, finding a significantly higher methylation rate in cancer tissues compared to adjacent normal tissues.
Results indicated that hypermethylation of hsa-miR-124a is linked to increased levels of Rb and CDK6 proteins and correlates with several clinical factors such as tumor size and lymphatic metastasis, suggesting a role in the progression of gastric cancer.