Publications by authors named "Jia-xin Liu"

To study the pollution characteristics and ecological risks of heavy metals in tailings ponds is an important prerequisite for protecting the surrounding environment and human health. The total amount and morphology of five "toxic" heavy metals (As, Cr, Cd, Pb, and Hg) in Kafang tin tailings pond were determined. Based on the aforementioned, we analyzed the distribution characteristics of heavy metals.

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Metal-free photosensitizers for the construction of low-cost and eco-friendly dye-sensitized photoelectrochemical cells (DSPECs) have recently been greatly improved, but the optimization of water oxidation catalysts (WOCs) used in DSPECs based on metal-free dyes has received little attention. Herein, a series of polymer networks (RuTPA, RuCz, RuPr and RuTz) assembled by ruthenium WOCs (RuCHO) with various organic donors are constructed and combined with calixarene dyes to prepare DSPEC devices. The FTO|TiO|C4BTP+RuTPA photoanode shows the best performance with 85 % Faraday efficiency for oxygen production and 477 μA cm photocurrent density after 200 s chopping irradiation at 0 V vs.

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CD3(+) CD4(-) CD8(-) double negative T cells (DNTs) manifest themselves in autoimmune diseases and associated inflammation. In the central nervous system, the increased presence of DNTs is associated with the progression of neurological conditions and brain injury. Active DNTs that produce IL-17 have been regarded as a pro-inflammatory phenotype.

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The high heterogeneity within and between breast cancer patients complicates treatment determination and prognosis assessment. Treatment decision-making is influenced by various factors, such as tumor subtype, histological grade, and genotype, necessitating personalized treatment strategies. Prognostic outcomes vary significantly depending on patient-specific conditions.

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Background: Complete transperitoneal nephroureterectomy (CTNU) in a single-position is an advanced surgical technique for the treatment of upper urinary tract urothelial carcinoma (UTUC), performed entirely through a transperitoneal approach without the need for patient repositioning. Indocyanine green (ICG) has been extensively studied in urologic surgery, with applications ranging from sentinel lymph node mapping to tumor localization. This study aimed to evaluate the performance of retrograde ureteral fluorescence imaging in CTNU.

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  • Environmental pollution, specifically heavy metals, may negatively impact the prognosis of advanced high-grade serous ovarian cancer (HGSOC), but current evidence is limited.
  • A study involving 159 deceased HGSOC patients and 159 matched living patients analyzed urinary levels of five heavy metals—arsenic, cadmium, chromium, mercury, and lead—using statistical models to determine associations with overall survival (OS).
  • The results showed significant links between high levels of arsenic, cadmium, mercury, and lead in urine and poorer OS, with lead being the most influential in negatively affecting survival, indicating a need for further research.
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  • Meta-analyses have shown mixed results regarding the relationship between whole blood cell count-derived indexes (NLR, PLR, LMR) and cancer prognosis, highlighting the need for a clearer understanding of the evidence quality.* ! -
  • The review analyzed 694 associations from 224 articles, revealing that 97.8% of these studies were rated as moderate to high quality based on AMSTAR criteria.* ! -
  • Although there were four associations with strong evidence, many others were only suggestive, indicating a need for further research to clarify these relationships and determine causality.* !
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Background: There is currently a lack of comprehensive evidence regarding the correlation between Alternate Mediterranean Diet (AMED) and the survival of patients with ovarian cancer (OC). This prospective cohort study first assessed the association of AMED, not only pre-diagnosis and post-diagnosis but also the change from pre-diagnosis to post-diagnosis with OC survival.

Methods: A total of 560 OC patients were included in the study, and their dietary intake was assessed using a reliable 111-item food frequency questionnaire.

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  • A study was conducted to assess the prevalence of subthreshold depression among Chinese college students, revealing a significant rate of approximately 39.7% among 8,934 participants.
  • Factors such as being female, having chronic illnesses, experiencing financial debt, facing challenges in family communication, and feeling high perceived pressure were linked to a higher risk of developing subthreshold depression.
  • The research suggests that strong family communication, better perceived social support, and higher self-efficacy may serve as protective factors against subthreshold depression, highlighting the importance of timely screening for at-risk students.
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Reservoir computing (RC) has attracted considerable attention for its efficient handling of temporal signals and lower training costs. As a nonlinear dynamic system, RC can map low-dimensional inputs into high-dimensional spaces and implement classification using a simple linear readout layer. The memristor exhibits complex dynamic characteristics due to its internal physical processes, which renders them an ideal choice for the implementation of physical reservoir computing (PRC) systems.

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  • Research shows that per- and polyfluoroalkyl substances (PFASs) have possible links to various health issues, but more studies are needed for conclusive findings.
  • A systematic review examined 157 meta-analyses assessing PFAS health impacts, indicating moderate-to-high quality results for most studies, particularly highlighting significant associations with low birth weight and immune response.
  • While strong evidence connects some PFASs to specific health outcomes, many associations still lack certainty, with a substantial number of potential health effects needing further investigation.
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Fuchs endothelial corneal dystrophy (FECD) is one of the most common corneal diseases that causes loss of visual acuity in the world. FECD is a genetically and pathogenetically heterogeneous disease that results in the failure of corneal endothelial cells to maintain fluid balance and functional homeostasis of the cornea. Corneal edema, central guttae formation, and bullae development are common corneal pathologies.

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Drug discovery often begins with a new target. Protein-protein interactions (PPIs) are crucial to multitudinous cellular processes and offer a promising avenue for drug-target discovery. PPIs are characterized by multi-level complexity: at the protein level, interaction networks can be used to identify potential targets, whereas at the residue level, the details of the interactions of individual PPIs can be used to examine a target's druggability.

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Our objective was to investigate the status and influence of myopia among primary school students in Fushun, Liaoning Province, China. We aimed to provide a theoretical and epistemological basis for implementing myopia prevention initiatives. We employed cluster sampling and surveyed 5216 primary school students from grades 1-6 across eight primary schools in Fushun City.

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  • Viral infections throughout history have led to significant negative effects on a global scale, driven by human-virus protein interactions (PPIs) that inform both viral infection and host immune responses.
  • The study emphasizes the importance of mapping these PPIs to understand viral invasion and protein functions, highlighting advancements in technology and AI that have accelerated PPI mapping over the last decade.
  • This work reviews various methods for constructing large-scale human-virus PPI maps, aiming to provide researchers with a comprehensive toolkit to enhance our understanding of human-virus relationships.
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The objective of this study was to explore the perioperative outcomes of single-plane posterior retroperitoneoscopic adrenalectomy (SPRA) guided by indocyanine green dye (ICG) fluorescence imaging. A retrospective analysis of patients who underwent SPRA from April to September 2023 in our center was conducted. Patients were divided into the ICG group and the non-ICG group, based on whether they received intraoperative ICG fluorescence guided or not.

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Guided by H NMR spectroscopic experiments using the characteristic enol proton signals as probes, three pairs of new tautomeric cinnamoylphloroglucinol-monoterpene adducts (-) were isolated from the buds of . Their structures with absolute configurations were established by spectroscopic analysis, modified Mosher's method, and quantum chemical electronic circular dichroism calculation. Compounds - represent a novel class of cinnamoylphloroglucinol-monoterpene adducts featuring an unusual C-4-C-1' linkage between 2,2,4-trimethyl-cinnamyl--triketone and modified linear monoterpenoid motifs.

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Purpose: Bladder neck contracture (BNC) is a rare but intolerant complication after transurethral surgery of prostate. The present study aims to investigate the incidence and risk factors of BNC in patients diagnosed benign prostate hyperplasia (BPH) and following transurethral resection or enucleation of the prostate (TURP/TUEP).

Methods: This retrospective study included 1008 BPH individuals who underwent transurethral surgery of the prostate between January 2017 and January 2022.

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Seven new secoiridoid glycosides (1-7), together with a known analogue (8), were isolated from the fruits of Ligustrum lucidum. Their structures with absolute configurations were determined by HR-ESI-MS, 1D and 2D NMR, and electronic circular dichroism (ECD) spectroscopic analysis, as well as biogenetic consideration. Compounds 1 and 2 are the first examples of secoiridoid glycoside dimers featuring a rare rearranged oleoside-type secoiridoid moiety, and compounds 3-7 represent a new class of oleoside-type secoiridoid glycosides with unusual stereochemistry at C-1 position.

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Background: The gastrointestinal (GI) tract is the second most frequent extranasal involvement site for ENKTL. This study aimed to explore the clinicopathological features, treatment models, survival outcomes, and prognosis of gastrointestinal ENKTL (GI-ENKTL).

Methods: The clinical data of GI-ENKTL patients were extracted from the China Lymphoma Collaborative Group (CLCG) database and were analyzed retrospectively.

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Paclitaxel-treated patients frequently experience chemotherapy-induced peripheral neuropathy (CIPN) and mood changes, such as anxiety. Layer II/III of the medial prefrontal cortex (mPFC) is vital for generating pain and emotions. However, it is unclear whether glutamatergic neurons in layer II/III of the mPFC are involved in regulating paclitaxel-induced neuropathic pain and anxiety.

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  • Paclitaxel (PTX) leads to cognitive impairment known as "chemo-brain," and this study investigates whether necroptosis contributes to this condition.
  • Researchers used C57bl/6n mice to assess the effects of different PTX doses on cognition, necroptosis, and microglia's role in inflammation.
  • Results showed significant cognitive decline linked to increased necroptosis and inflammatory markers; pre-treatment with Gdcl3 alleviated some cognitive issues, suggesting a potential therapeutic pathway for managing chemo-brain.
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The incidence of re-tearing after rotator cuff repair is very high. The main reason is that the tendon-osseous junction after the operation is scar healed. In response to this problem, research in recent years has focused on the application of grafts, including cell transplantation, periosteum transplantation, cartilage transplantation, and biosynthetic transplantation.

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