Publications by authors named "Jia-xiang Yin"
Article Synopsis
- An emerging zoonotic pathogen linked to human granulocytic anaplasmosis was studied in small mammals to assess its prevalence, genetic diversity, and risk factors in western Yunnan province, China.
- Through seasonal capture and nested-PCR testing on spleen samples, researchers found a 0.93% infection rate among 1,605 small mammals across various species and habitats, revealing significant variations in infection rates.
- The study highlighted the pathogen's genetic diversity with distinct clades identified and underscored the importance of ongoing monitoring and the One Health approach for effective public health and disease surveillance.
Background: Scrub typhus has become widespread across various regions in China in recent decades, causing a considerable burden on residents. While meteorological variables significantly impact the spread of scrub typhus, there is insufficient quantitative evidence illustrating this association in known high-endemic areas.
Methods: A distributed lag non-linear model was applied to explore the relationship between meteorological parameters and scrub typhus incidence from 2010 to 2019 in Baoshan City, western Yunnan Province, China.
Background: Small mammals serve as the main reservoir for and as a proxy indicator of the potential risk of transmission from nature to humans. They offer a valuable early warning for human infection. Nevertheless, geographical variations in the impact of the host on the occurrence of infection are underestimated.
View Article and Find Full Text PDFSmall mammals can transmit and serve as a reservoir for () in nature by carrying infected mites. In Yunnan, one of China's main foci of scrub typhus, etiological evidence and genetic diversity for is limited. A total of 2538 small mammals were captured seasonally from 2015 to 2016 in the three counties of Yunnan, and the spleen or liver tissue was examined for based on 56 kDa nPCR.
View Article and Find Full Text PDFGenetic Evolution Analysis and Host Characteristics of Hantavirus in Yunnan Province, China.
Int J Environ Res Public Health
October 2022
Article Synopsis
- - The study investigates the ongoing problem of hantavirus (HV) causing hemorrhagic fever with renal syndrome (HFRS) in Yunnan Province, China, noting a lack of comprehensive research and understanding of the virus's molecular epidemiology and host characteristics in the region.
- - Researchers captured 488 murine-shaped animals across three locations and found that 2.46% were infected with HV, discovering a new subtype of Seoul virus (SEOV) in a rare rat species in Lianghe County, identified as YNLH-K40 and YNLH-K53.
- - Phylogenetic analysis suggests this new subtype is closely related to another virus known to cause high HFRS incidence, indicating potential implications for human health
The Yunnan province has one of the most serious outbreaks of the plague epidemic in China. Small mammals and fleas are risk factors for the occurrence of plague in commensal plague foci. Understanding the relationship between fleas and small mammals will help control fleas and prevent the onset of the plague.
View Article and Find Full Text PDF[Predictors for abundance of Rattus tanezumi in households of commensal rodent plague foci].
Zhonghua Liu Xing Bing Xue Za Zhi
February 2013
Objective: To explore the predictors on the abundance of Rattus (R.) tanezumi in households of commensal rodent plague foci.
Methods: Thirty natural villages that experienced previous plague cases in Lianghe county, Yunnan province, were selected followed by random selection of 20 households in each village through computer technique.
[Detection and preliminary study of a family carrying a CCR5Δ32 deletional mutation].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
August 2012
Objective: To investigate the frequencies of chemokine (C-C motif) receptor 5 gene (CCR5)Δ32 deletional mutation of in Han and Dai populations from Yunnan province. Immortalized cell lines were derived from a family carrying the CCR5Δ32 mutation.
Methods: Blood samples of 346 Han and 355 Dai individuals were collected for genotyping.
Background: From 1990 to 2006, fifty-five natural villages experienced at least one plague epidemic in Lianghe County, Yunnan Province, China. This study is aimed to document flea abundance and identify predictors in households of villages with endemic commensal rodent plague in Lianghe County.
Methods: Trappings were used to collect fleas and interviews were conducted to gather demography, environmental factors, and other relevant information.
Background: Ninety-one rodent plague epidemics have occurred in Lianghe county, Yunnan Province, China, between 1990 and 2006. This study aimed to identify predictors for the presence and abundance of small mammals in households of villages endemic for rodent plague in Lianghe county.
Results: Rattus flavipectus and Suncus murinus were the two species captured in 110 households.