Publications by authors named "Jia-lu Yao"

Aim: To evaluate the effectiveness and safety of nutritional interventions (i.e. nutritional support, dietary patterns and dietary supplements) on cognitive function in cancer survivors.

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ATP-sensitive K (K) channel couples membrane excitability to intracellular energy metabolism. Maintaining K channel surface expression is key to normal insulin secretion, blood pressure and cardioprotection. However, the molecular mechanisms regulating K channel internalization and endocytic recycling, which directly affect the surface expression of K channels, are poorly understood.

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Article Synopsis
  • FOLFOX regimens, consisting of 5-fluorouracil and oxaliplatin, are commonly used to treat colorectal cancer (CRC), but drug resistance poses a significant challenge to effective treatment.
  • Researchers used various transcriptomic datasets and weighted gene co-expression network analysis (WGCNA) to identify C3 as a key gene linked to resistance against FOLFOX and CRC recurrence.
  • High expression levels of C3 were associated with poor survival outcomes and reduced sensitivity to oxaliplatin, suggesting that C3 could serve as a potential biomarker for improving CRC treatment decisions.
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Maize is one of the most vital staple crops worldwide. G proteins modulate plentiful signaling pathways, and G protein-coupled receptor-type G proteins (GPCRs) are highly conserved membrane proteins in plants. However, researches on maize G proteins and GPCRs are scarce.

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Purpose: To study the effect of quality control circle activity on improving nursing quality of patients with periodontitis.

Methods: One hundred and twenty patients with periodontitis admitted to our hospital from January 2016 to December 2017 were selected and divided into experimental group and control group according to the principle of random control, with 60 patients in each group. Patients in both groups received supragingival scaling, subgingival scaling and related symptomatic treatment, patients in the experimental group conducted nursing under the guidance of quality control circle, while patients in the control group received routine nursing.

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The authors are retracting this article [1]. In their recent work the authors have found that the degree of fibrosis in the different walls of the left atrium in pigs with hypertensive cardiomyopathy is the same. Sirius Red staining (another method to test for fibrosis) showed that there was no difference between the different walls.

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Introduction: It has been reported that APOA1 -75G/A polymorphism might be associated with susceptibility to coronary artery disease (CAD). Owing to mixed and inconclusive results, we conducted a meta-analysis to systematically summarize and clarify the association between APOA1-75G/A polymorphism and the risk of CAD.

Material And Methods: A systematic search of studies on the association of single nucleotide polymorphisms (SNP) with susceptibility to CAD was conducted.

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Background: Previous case-control studies on association between KCNE1 G38S polymorphism and risk of atrial fibrillation (AF) have been published but because of the conflicting results and small sample size of individual studies, the consolidated result is still controversial.

Objectives: The aim of this study was to explore the relationship between KCNE1 G38S polymorphism and risk of AF.

Methods: We performed a comprehensive literature search on PubMed, Embase, OVID, Web of Science, Wan Fang, and CNKI databases up to March 10, 2017 in English and Chinese languages.

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Recently a large number of investigations have implicated the association between the chemokine CXC ligand 12 gene polymorphism (rs1746048) and risk of coronary heart disease (CHD), but the results remain debatable. The aim of our study was to provide more compelling evidence for the relationship between rs1746048 and CHD risk. Studies eligible for this meta-analysis were identified through electronic search of PubMed, EMBASE, and CNKI.

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Heart failure with preserved ejection fraction (HFpEF), which is a primary driver of morbidity and mortality, accounts for approximately half of all heart failure cases. Therefore, it is essential to develop preclinical animal models for HFpEF pharmacological treatment strategies. We created a porcine model of severe hypertension and hyperlipidemia by using a combination of deoxycorticosterone acetate (DOCA, 100 mg kg), Western diet (WD) and angiotensin II infusion.

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To investigate the relationship between KCNN3 SNP (single-nucleotide polymorphism) rs13376333 and risk of atrial fibrillation (AF) and to provide evidence for prevention and treatment for AF.The PubMed, Embase, OVID, Cochrane library, CNKI, and Wan Fang databases were searched to identify studies on the relationship between KCNN3 SNP rs13376333 polymorphism and atrial fibrillation. Two authors performed independent article reviews and study quality assessment using the Newcastle-Ottawa Scale (NOS) checklist.

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Background: To investigate the relationship between angiotensinogen (AGT) gene M235T polymorphism and hypertrophic cardiomyopathy (HCM) to explore the potential role of the AGT polymorphism in HCM.

Methods: PubMed, Embase, OVID, Cochrane library, CNKI, Wan Fang Database were searched to identify the studies involving AGT M235T polymorphism and HCM. Two authors performed independent literature review and study quality assessment using the Newcastle-Ottawa Scale (NOS) checklist.

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Objective: To study and compare the difference on the therapeutical effectiveness between paper splint adduction fixation and plaster abduction fixation in Bennett fracture.

Methods: In the study, seventy outpatient were selected from October 2005 to April 2007, and devided into two groups randomly involving experiment group (35 cases with paper splint adduction fixation) and control group (35 cases with plaster abduction fixation). After the fracture clinical healed and removed fixation, the patients had been followed up 6 months.

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