In this paper, we described a palladium/norbornene-catalyzed -C-H phosphormethylation of aryl iodides using XCHP(O)RR', offering a reliable method for the modular synthesis of polysubstituted α-phosphorylated arenes. Alkenylation, hydrogenation, cyanation, methylation, and arylation were all viable termination steps compatible with the reaction. This method demonstrates excellent functional group tolerance and can be extended to the late-stage modification of bioactive molecules.
View Article and Find Full Text PDFWe theoretically present the waveform controls of terahertz (THz) radiations generated from homogeneous and rippled plasma within inhomogeneous external electrostatic field. The Particle-in-cell (PIC) simulations is implemented to demonstrate generation and controllability of three types of THz pulses: single frequency THz pulse in homogeneous plasma, broadband THz pulse and dual frequency THz pulse in rippled plasma. The single frequency THz pulse can be tuned via shifting the knob of electron density of homogeneous plasma.
View Article and Find Full Text PDFBackground: Chronic diseases cause a tremendous burden to the military medical system. However, the prevalence rates of major chronic diseases among military officers remain unclear in China.
Methods: China National Knowledge Infrastructure (CNKI), Wanfang Database, VIP Database for Chinese Technical Periodicals (VIP), PubMed and Web of Science were searched for studies (from 2000 to 2016) concerning 6 major chronic diseases: hypertension, hyperlipidemia, diabetes mellitus, heart diseases, cerebrovascular diseases, and chronic obstructive pulmonary diseases (COPD) in Chinese military officers following strict inclusion and exclusion criteria.
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi
June 2016
Objective: To screen for the Echinococcus granulosus 01883(Eg-01883) specifically expressed at the protoscolex period, clone and express this molecule as well as analyse its immunogenicity.
Methods: Eg-01883, which is highly expressed at the protoscolex period but not in oncosphere, was screened by analysing the published mRNA sequences of E. granuolosus.