[Expression of Toll-like receptors in mononuclear cells from children with acute rotavirus diarrhea].

Objective: Rotavirus is the single most common cause of severe dehydrating diarrhea in young children worldwide, but the pathogenesis and immunity against this disease are not completely understood. A prospective study was conducted to assess gene expression of toll-like receptors (TLR) in children with acute rotavirus diarrhea.

Methods: Seventy-five children with acute rotavirus diarrhea and 38 control children were enrolled in this study from Sep.