Publications by authors named "Jia-Ying Dai"
We, for the first time, disclosed a simple and efficient strategy for the late-stage functionalization of primary sulfonamides by diazotization, leading to sulfonyl chlorides, sulfonates, and complex sulfonamides. This protocol obviates the requirement for the prefunctionalization of sulfonamides. Its applicability is exemplified by the late-stage functionalization of sulfonamide-type drugs.
View Article and Find Full Text PDFObjective: Local combined systemic therapy has been an important method for the treatment of unresectable hepatocellular carcinoma (HCC).The purpose of this study was to compare the effectiveness and safety of transarterial chemoembolization (TACE) plus Sorafenib versus TACE plus Apatinib for treating patients with unresectable HCC.
Methods: The clinical data of patients with unresectable HCC who were treated with TACE plus Sorafenib or TACE plus Apatinib at 5 Chinese medical centers between January 2016 and December 2020 were retrospectively analyzed.
Article Synopsis
- - A range of piperidines and pyrrolidines with CF and CHF groups were successfully synthesized using visible light photocatalysis with CFSONa and CHFSONa.
- - The process employs a radical cascade that allows for multiple reactions, including tri- and difluoromethylation as well as arylation of unactivated alkenes.
- - This method highlights its advantages such as mild conditions and the absence of additives and transition metals, while also increasing the variety of possible chemical structures derived from compounds like benzimidazole and indole.