[Study of salivary metabonomics in patients with oral squamous cell carcinoma and leukoplakia].

Purpose: The objective of this study was to detect and analyze the existence of differential metabolites from saliva of patients with oral squamous cell carcinoma(OSCC) by metabonomics method, and to evaluate its application value on clinical diagnosis or screening of OSCC.

Methods: The collected saliva samples for OSCC patients, oral leukoplakiac(OLK) patients who were pathologically diagnosed and met the inclusion criteria were analyzed using metabonomics methods (GC-TOF-MS). The results were analyzed by principal component analysis and orthogonal partial least squares discriminant analysis using SIMCA software.

[Distribution Characteristics and Health Risk Assessment of Thirteen Sulfonamides Antibiotics in a Drinking Water Source in East China].

Trace levels of residual antibiotics in drinking water sources may threaten public health and becomes a serious issue in modern society. Occurrence and distribution of 13 sulfonamides antibiotics in a drinking water source in East China were investigated using solid phase extraction-high performance liquid chromatography-tandem mass spectrometry. The results revealed that all 13 sulfonamides were detected with the total concentrations ranging from 10.