[Spatiotemporal variability characteristics and driving forces of land use in the Pan-Pearl River Basin, China].

The Pan-Pearl River Basin is a bridgehead for China's reform and opening-up and the construction of the Belt and Road at Sea, with vital strategic significance in Chinese overall development. Land use data and climate and socio-economic indicators were integrated to probe the spatiotemporal change and its driving forces of land use in the Pan-Pearl River basin with ArcGIS spatial analysis tool and SPSS factor analysis tool. Results showed that land use in the Pan-Pearl River Basin significantly changed between 1990 and 2015, with decreases of the area of paddy field and woodland and rapid increases of urban land and other construction land.

Establishment and characterization of the gemcitabine-resistant human pancreatic cancer cell line SW1990/gemcitabine.

Due to its rapid progression, metastasis and resistance to chemotherapy, pancreatic cancer is one of the most malignant tumor types to affect the digestive system. Gemcitabine chemotherapy is typically the first choice of treatment for advanced pancreatic cancer; however, chemoresistance is a major obstacle to successful treatment. In order to elucidate the underlying mechanisms of gemcitabine resistance in pancreatic cancer, the drug-resistant cell line SW1990-gemcitabine (SW1990-GZ) was established using the human pancreatic cancer cell line SW1990.