Deficiency of hepatokine orosomucoid1 aggravates NAFLD progression in mice.

Orosomucoid (ORM) is an important hepatokine that regulates metabolism. Previous report showed that isoform ORM2 but not ORM1 could downregulate lipogenic genes and ameliorate hepatic steatosis in obese mice, thereby categorizing ORM2 as a promising candidate for therapeutic intervention in nonalcoholic fatty liver disease (NAFLD). However, our previous studies found that mice lacking ORM1 gradually developed an obese phenotype with severe hepatic steatosis at the age of 24 weeks.

Cyanidin-3-rutinoside from Mori Fructus ameliorates dyslipidemia via modulating gut microbiota and lipid metabolism pathway.

Dyslipidemia is responsible for pathologies of cardiovascular diseases and gut microbiota plays an essential role in lipid metabolism. Dietary supplementation is an important supplement to medicine in management of dyslipidemia. Mori Fructus is a popular Asia medical food with various pharmacological benefits including anti-hyperlipidemia.

Palladium Catalyzed Annulation of -Iodo-Anilines with Propargyl Alcohols: Synthesis of Substituted Quinolines.

A palladium catalyzed annulation of -iodo-anilines with propargyl alcohols for the synthesis of substituted quinolines has been developed. The reaction tolerates diverse functional groups under mild conditions, providing direct access to 2,4-disubstituted quinolines from easily available starting materials. A broad range of 2,4-disubstituted quinolines were efficiently prepared in good to excellent yields.

Ignatzschineria rhizosphaerae sp. nov. Isolated from Rhizosphere Soil of the Halophyte Kalidium cuspidatum.

A Gram-staining negative, non-motile, aerobic, rod-shaped bacterium, designated strain HR5S32, was isolated from rhizosphere soil of the halophyte Kalidium cuspidatum, in Tumd Right Banner, Inner Mongolia, northern China. Strain HR5S32 grew at 10-40 °C (optimum 30 °C), pH 6.0-10.

Corynebacterium kalidii sp. nov, an endophyte from a shoot of the halophyte Kalidium cuspidatum.

A Gram-stain-positive, non-motile, rod-shaped bacterial strain designated LD5P10 was isolated from a root of Kalidium cuspidatum, in Tumd Right Banner, Inner Mongolia, China. The strain grew at 4-40 ℃ (optimum 30 ℃), and pH 5.0-10.

[Adaptability of to sewage sludge and its characteristics of nutrient and heavy metal uptake and accumulation].

, an important fast-growing economic tree species in China, has the advantages of strong adaptability, high-biomass, and high bioconcentration of heavy metals. Sewage sludge contains a great deal of nutrients and heavy metals. Planting with sewage sludge can achieve the goals of sewage sludge remediation as well as resources production of .

Hepatoprotective Polysaccharides from : Purification, Structural Characterization, and Their Mechanism.

Traditional Chinese Medicine is generally used as a decoction to guard health. Many active ingredients in the decoction are chemical ingredients that are not usually paid attention to in phytochemical research, such as polysaccharides, etc. Based on research interest in Chinese herbal decoction, crude polysaccharides from (GCP) were purified to obtain two relatively homogeneous polysaccharides, a neutral polysaccharide (GNP), and an acid polysaccharide (GAP) by various chromatographic separation methods, which were initially characterized by GC-MS, NMR, IR, and methylation analysis.

The adipokine orosomucoid alleviates adipose tissue fibrosis via the AMPK pathway.

The excess deposition of underlying extracellular matrix (ECM) in adipose tissue is defined as adipose tissue fibrosis that is a major contributor to metabolic disorder such as obesity and type 2 diabetes. Anti-fibrosis therapy has received much attention in the treatment of metabolic disorders. Orosomucoid (ORM) is an acute-phase protein mainly produced by liver, which is also an adipokine.

Effects of sewage sludge and other wastes application on the growth and element uptake of in abandoned rare-earth mine soil.

The wastes such as sewage sludge (SS) can be used to amend soil of abandoned rare-earth mine land (ARL). The energy plant could be used as a pioneer tree species in the ARL. In a pot experiment to address the responses of growth and element uptake of , three treatments were established: adding SS to the soil of ARL (T), adding SS and bagasse to the soil of ARL (T), adding SS, bagasse and passivator to the soil of ARL (T), with the untreated soil of the ARL as the control (CK).

[Innovative ultrasound transducers-purewave crystal technology and its applications].

This article is to introduce the dramatic improvements in efficiency, sensitivity and bandwidth of the ultrasound transducers--PureWave Crystal Technology.

[Target volume calculation methods based on PET-CT images].

The applications of PET-CT have developed from qualitative analysis to quantitative analysis. Target volume is important for tumor biological volume defining, tumor isotope therapy, organ function evaluation, acceptor affinity calculation, and pharmaceutical metabolic kinetics. Many factors work on the target volume calculation, such as PET image acquisition mode, scatter correction, attenuation correction, reconstruction method, image display mode, positron pharmacy.