Effect of vitamin supplementation on polycystic ovary syndrome and key pathways implicated in its development: A Mendelian randomization study.

Background: Many epidemiologic investigations have explored the relationship between viatmins and polycystic ovary syndrome (PCOS). However, the effectiveness of vitamin, vitamin-like nutrient, or mineral supplementation in reducing the risk of PCOS remains a subject of debate.

Aim: To investigate the impact of plasma levels of vitamins A, B12, D, E, and K on PCOS and key pathways implicated in its development, namely, insulin resistance, hyperlipidemia, and obesity, through Mendelian randomization (MR) analysis.

Study on Multifunctional Composite Nanomaterials for Controlled Drug Release in Biomedicine.

Nanoscience is a highly comprehensive, interdisciplinary discipline based on many advanced science and technology, and has developed very rapidly in the past few decades. Nanoscience and technology has been widely used in many fields such as biomedicine, materials science, chemistry, physics, and electronic information engineering. Nanomaterials are widely used due to their many excellent properties such as quantum size effects, small size effects, surface effects, and tunneling effects, and have become hot research areas.

Early Detection of Silent Myocardial Impairment in Drug-Naive Patients With New-Onset Systemic Lupus Erythematosus: A Three-Center Prospective Study.

Objective: Cardiac magnetic resonance imaging (MRI) has enabled the assessment of myocardial features, from tissue characteristics to functional changes, in patients with systemic lupus erythematosus (SLE). Echocardiography, however, detects cardiac decompensation. This study was undertaken to investigate the use of cardiac MRI to explore early warning signs of silent cardiac involvement and determine treatment timing in SLE.