sp. nov., isolated from intertidal sand of the Yellow Sea.

A novel species of the genus , designated ASW11-118, was isolated from an intertidal sand sample of the Yellow Sea, PR China. Growth of strain ASW11-118 occurred at 10-40 °C (optimum, 28 °C), pH 5.5-8.

The role of integrin-β/FAK in cyclic mechanical stimulation in MG-63 cells.

Objective: This study aims to explore the function of Integrin-β/FAK in the mechanical signal transduction and the connection with downstream ERK signal pathways.

Methods: Human osteosarcoma MG63 cell lines were used in this study. The effects of mechanical strain on the Integrin-β₁ expression, FAK and ERK signal pathway in Human osteosarcoma MG63 cells were detected using RT-PCR and Western-blotting methods.

Stretch-inducible expression of connective tissue growth factor (CTGF) in human osteoblasts-like cells is mediated by PI3K-JNK pathway.

To explore the possible role for connective tissue growth factor (CTGF) during tooth movement, we evaluated CTGF gene and protein expression in MG-63 cells subjected to cyclic stretch. Cyclic stretch caused a time-dependent increase in CTGF mRNA and protein levels.Inhibition of p38 MAP kinase or ERK activation did not affect cyclic stretch-induced CTGF expression.