deficiency causes male sterility and testis abnormal in .

Introduction: It has been established that encodes E3 ubiquitin ligase, which determines the specificity of substrate binding during protein ubiquitination and has been associated with various functions of the nervous system but not the reproductive system. Herein, we explored the role of on fertility with a .

Methods: Different knockdown flies were established using the UAS/GAL4 activating sequence system.