- Medullary Thyroid Carcinoma (MTC) is a rare but aggressive thyroid cancer that develops from C-cells, which produce calcitonin, and is known for its high potential to spread.
- The genetics of MTC, especially involving the RET gene and the RAS gene family, have been crucial in understanding the disease and finding possible treatment targets.
- This review highlights recent progress in MTC genetics, new precision therapies, and potential biomarkers, discussing their significance for clinical practice and future research directions.