[Relationship between the prophase growth of knots and the radial growth of trunk in ].

We analyzed the differences in knot property of linear and curved knots of dominant, medium, and inferior wood with thirty-three trees from Mengjiagang Forest Farm and Linkou Forestry Bureau in Heilongjiang Province. We divided the 33 trees into two groups according to the height of the site index. We constructed a trunk diameter growth models to explore the connection, between the knot growth inflection points and the successive growth of diameter, and to screen for the types that had a weaker impact on wood quality.

[Response of branch attributes of to climate variables].

We established a mixed-effects model incorporating climatic factors for the base diameter and length of the primary branches of using stepwise regression, based on climatic data from a total of 40 standard plots located in Xiaolongshan, Gansu Province, Changlinggang Forest Farm in Jianshi County, Hubei Province, and Dagujia Forest Farm in Qingyuan County, Liaoning Province, as well as the data from 120 sample trees. Additionally, we created prediction charts for the fixed effects portion of the optimal mixed model to determine the relationship between climatic factors and base diameter and branch length, to explore the differential response of branches to climatic variables. The results showed that the base diameter mixing model with annual mean temperature and water vapor deficit and the branch length mixing model with annual mean temperature had the best fitting effect, with of 0.

Effects of thinning on structural complexity of plantation.

In this paper, we collected the individual tree point cloud data in the plots of plantations with different thinning intensities in Mengjiagang Forest Farm, applied the fractal analysis theory to extract box dimensions () on MATLAB platform, and characterized the structural complexity of . We assessed the effect of different thinning intensities and tree attributes on the structural complexity of . The results showed significant differences in between control (CK: 1.

Growth difference of planted from different provenances in Maoer Mountain, China.

In order to analyze the growth pattern of tree height of planted and screen the provenances with fastest growth, we grouped the provenances using the differences in tree height, diameter at breast height (DBH) and volume of timber of 234 individuals of planted from 26 provenances in Maoershan Experimental Forest Farm. We constructed the growth equation for tree height by combining the base models of Gompertz, Korf, Richards, Logistic, and Schumacher, and then selected the optimal one. We introduced the prove-nance grouping as a dummy variable into the base model, and evaluated the optimal tree height growth equation by a comprehensive evaluation of the model according to the coefficient of determination (), the root-mean-square error (RMSE), the Akaikei Information Criterion (AIC), and the model's predictive precision ().

Electroacupuncture activates AMPKα1 to improve learning and memory in the APP/PS1 mouse model of early Alzheimer's disease by regulating hippocampal mitochondrial dynamics.

Objective: Studies have shown that electroacupuncture (EA) can alleviate cognitive impairments from Alzheimer's disease (AD) by regulating the expression of adenosine monophosphate-activated protein kinase (AMPK), but the specific mechanism involved remains to be elucidated. Therefore, this study explores the potential mechanism by which EA improves cognitive function from the perspective of mitochondrial dynamics.

Methods: The four-month-old transgenic mice with amyloid precursor protein (APP)/presenilin 1 (PS1) and AMPKα1-subunit conditional knockout (AMPKα1-cKO) were used for experiments.

Construction of universal equations for knot attributes of three coniferous species.

We constructed base model, dummy variable model, and mixture model with three variables including knot diameter, loose knot length, and sound knot length with three typical coniferous species, , , and var. , from the Linkou Forestry Bureau and Mengjiagang forest farm in Heilongjiang Province in 2020. We analyzed the differences in knot properties among different tree species and simplified the modeling work.

Cytoreductive surgery offers prognostic benefits in metastatic gastrointestinal stromal tumors with generalized progression following imatinib therapy: a single institute retrospective study.

Background: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. Distant metastasis has been detected in approximately 50% of GIST patients at the first diagnosis. The surgical strategy for metastatic GIST with generalized progression (GP) after imatinib therapy remains unclear.

Mechanistic analysis of resveratrol in cardiac hypertrophy by network pharmacology and animal experiments.

Resveratrol (Res) serves a protective role in hepatic, cardiovascular and autoimmune hypertrophic disease. However, the mechanisms by which Res ameliorates cardiac hypertrophy have not yet been fully elucidated. In the present study, network pharmacology was used to construct a network and perform enrichment analysis to evaluate the effect of Res on cardiac hypertrophy.

Molecular Basis Underlying Hepatobiliary and Renal Excretion of Phenolic Acids of Roots (Danshen).

Phenolic acids are cardiovascular constituents (originating from the Chinese medicinal herb root/Danshen) of DanHong and many other Danshen-containing injections. Our earlier pharmacokinetic investigation of DanHong suggested that hepatic and/or renal uptake of the Danshen compounds was the crucial steps in their systemic elimination. This investigation was designed to survey the molecular basis underlying hepatobiliary and renal excretion of the Danshen compounds, i.

Emerging blood exosome-based biomarkers for preclinical and clinical Alzheimer's disease: a meta-analysis and systematic review.

Blood exosomes, which are extracellular vesicles secreted by living cells into the circulating blood, are regarded as a relatively noninvasive novel tool for monitoring brain physiology and disease states. An increasing number of blood cargo-loaded exosomes are emerging as potential biomarkers for preclinical and clinical Alzheimer's disease. Therefore, we conducted a meta-analysis and systematic review of molecular biomarkers derived from blood exosomes to comprehensively analyze their diagnostic performance in preclinical Alzheimer's disease, mild cognitive impairment, and Alzheimer's disease.

[Construction of the additive model system for heartwood, sapwoodand bark taper of plantation in different regions of Heilongjiang Province, China].

With the commonly used variable-exponent taper models developed by Kozak (1988), Muhairwe (1999), Lee (2003) and Kozak (2004), we aimed to develop taper functions of diameter outside bark (DOB), heartwood diameter (HD), sapwood width (SW), and bark thickness (BT) based on the data of 2977 discs from 103 sample trees of plantations under different conditions in Mengjiagang Forest Farm, Dongjingcheng and Linkou Forestry Bureau in Heilongjiang Province. We selected the optimal basic model after comparison. By using seemingly unrelated regression (SUR) method in the PROC MODEL of SAS software, we established an additive model system for the taper equations of DOB, HD, SW and BT.

Extraction of branch factors and model construction for plantation using terrestrial laser scanning (TLS).

Forest parameters could be estimated without damage using terrestrial laser scanning (TLS). In this study, 1266 sets of branch parameters, including branch height, branch chord length, branch length, branch angle, branch diameter and the branch arc height, of 26 trees were extracted based on TLS using point cloud processing software in the way of human-computer interaction. The average of extracted maximum relative height of the branches was 0.

Difluoromethylornithine attenuates isoproterenol-induced cardiac hypertrophy by regulating apoptosis, autophagy and the mitochondria-associated membranes pathway.

Myocardial hypertrophy is an independent risk factor of cardiovascular diseases and is closely associated with the incidence of heart failure. In the present study, we hypothesized that difluoromethylornithine (DFMO) could attenuate cardiac hypertrophy through mitochondria-associated membranes (MAM) and autophagy. Cardiac hypertrophy was induced in male rats by intravenous administration of isoproterenol (ISO; 5 mg/kg/day) for 1, 3,7 and 14 days.

Pharmacokinetics-based identification of pseudoaldosterogenic compounds originating from Glycyrrhiza uralensis roots (Gancao) after dosing LianhuaQingwen capsule.

LianhuaQingwen capsule, prepared from an herbal combination, is officially recommended as treatment for COVID-19 in China. Of the serial pharmacokinetic investigations we designed to facilitate identifying LianhuaQingwen compounds that are likely to be therapeutically important, the current investigation focused on the component Glycyrrhiza uralensis roots (Gancao). Besides its function in COVID-19 treatment, Gancao is able to induce pseudoaldosteronism by inhibiting renal 11β-HSD2.

[Prediction models of knot volume inside the stem for Korean pine plantation].

Based on 1207 knots from 49 sample trees of 29 standard plots of Korean pine plantations in Linkou and Dongjingcheng Forest Bureau of Heilongjiang Province, China, we extracted longitudinal sections of knots using the image processing software Digimizer and represented the shape of knots using two-dimensional scatter plots. According to the two-dimensional scatter plots, knots of Korean pine plantation were divided into three types: 1) alive knots (whole knot contained only sound knot portion); 2) non-occluded dead knots (whole knot contained both sound and loose knot portions); 3) occluded dead knots (the sound and loose portion of the knot were partially occluded by the bark). For all the three types of knots, the volume of sound knot was calculated by mathematical integral of the sound knot shape equation.

Therapy for Apnoea of Prematurity: A Retrospective Study on Effects of Standard Dose and Genetic Variability on Clinical Response to Caffeine Citrate in Chinese Preterm Infants.

Introduction: Apnoea of prematurity (AOP) is among the most common diagnoses in the neonatal intensive care unit. Caffeine treatment is a preferred treatment choice. However, neonatal caffeine therapy results in significant intersubject variability.

Prediction model system with dummy variables for carbon storage of larch plantation in Heilongjiang Province, China.

Based on monitoring data from fixed plots of larch plantation in Heilongjiang Province obtained in 2005 and 2010, we analyzed the relationship among stand variables of larch plantation in Heilongjiang Province and established site class index curve model and stand density index model. A two-stage least square method was used to establish a simultaneous equations system for predicting average basal area and carbon storage of stands. Together, they were called prediction model system for carbon storage of larch plantation in Heilongjiang Province.

Adoptive cell therapy of tolerogenic dendritic cells as inducer of regulatory T cells in allergic rhinitis.

Background: Regulatory T cells (Tregs) have become promising candidates for immunotherapy in allergic rhinitis (AR). The contributing role of tolerogenic dendritic cells (tDCs) in the augmentation of Tregs in AR remains to be determined.

Methods: The properties of tDCs in expanding Tregs and their potential to ameliorate AR were evaluated in vitro and in vivo.

[Change pattern of heartwood of Larix olgensis plantation.].

Based on the data of 1179 discs and whorls of 49 trees from larch (Larix olgensis) plantations located in Mengjiagang forest farm in Heilongjiang Province, China, we analyzed the longitudinal variation pattern of heartwood radius. The results showed that the heartwood radius decreased with the increases of tree height, which was basically the same as the trunk shape. The relationship between the xylem radius (XR), diameter at breast height (DBH) and cambial age (CA) with the heartwood radius was significant.

[Knot attributes of Korean pine plantation based on mixed effect model.].

Based on 1534 knot data from 60 sample trees in a Korean pine plantation in Mengjiagang Forest Farm, Heilongjiang Province, China, mixed effect model of knot attributefactors (knot diameter, sound knot length, year of death of knot and knot angle) of Korean pine plantation was established using NLMIXED and GLIMMIX procedures of SAS software. The prediction accuracy of models was compared using evaluation statistics, such as Akaike information criterion (AIC), Bayesian information criterion (BIC), -2Log likelihood(-2LL), and likelihood ratio test (LRT). Results showed that all of the mixed effect models that considered tree effect performed better than conventional fixed-effect models.