Publications by authors named "Jia-Qiang Hu"

Introduction: Monoclonal antibodies (mAbs) against cytokines and chemokines or their receptors promise to be a potential therapeutic option to address chronic obstructive pulmonary disease (COPD). We aim to provide a comprehensive literature review of the improvement in FEV1 and safety when comparing mAbs with conventional dichotomous agents.

Methods: We systematically searched 3 electronic databases (PubMed, EMBASE, and CENTRAL) up to August 1, 2023 to collect eligible randomized controlled trials (RCTs).

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Patients with type 2 diabetes mellitus (T2DM) are at higher risk for urinary tract infections (UTIs), which greatly impacts their quality of life. Developing a risk prediction model to identify high-risk patients for UTIs in those with T2DM and assisting clinical decision-making can help reduce the incidence of UTIs in T2DM patients. To construct the predictive model, potential relevant variables were first selected from the reference literature, and then data was extracted from the Hospital Information System (HIS) of the Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital for analysis.

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Article Synopsis
  • * The review addresses the lack of comprehensive literature regarding the structure-activity relationships and dosage effects of HMOs, detailing their structures and synthetic pathways.
  • * It also highlights recent findings on the health benefits of HMOs, focusing on how different structures interact with microorganisms and the impact of dosage based on various studies.
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The imbalance of reactive oxygen species is the main cause in aging, accompanied by oxidative stress. As the most abundant in human milk oligosaccharides (HMOs), 2'-Fucosyllactose (2'-FL) has been confirmed to have great properties in immunity regulation and anti-inflammatory. The research on 2'-FL is focused on infants currently, while there is no related report of 2'-FL for the elderly.

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Article Synopsis
  • The study aims to evaluate how auditory brainstem responses (ABR) can be used to objectively monitor anesthesia depth and awakening in children.
  • It involved 45 children receiving different types of anesthesia (propofol, fentanyl, or isoflurane) and measured the latencies of ABR waves in response to sound stimulation.
  • The results indicated that the latencies are positively correlated with anesthesia dosage and can help assess the degree of anesthesia, although fentanyl showed less sensitivity in monitoring.
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