The percolation phase transition of a continuum adaptive neuron system with homeostasis is investigated. In order to maintain their average activity at a particular level, each neuron (represented by a disk) varies its connection radius until the sum of overlapping areas with neighboring neurons (representing the overall connection strength in the network) has reached a fixed target area for each neuron. Tuning the two key parameters in the model, i.
View Article and Find Full Text PDFPulsatilla decoction (PD) is a classical prescription for the treatment of ulcerative colitis. Previous studies have demonstrated that the therapeutic efficacy of PD is closely associated with the activation of Farnesoid X receptor (FXR). The activity of FXR is regulated by apical sodium-dependent bile acid transporter (ASBT), and the FXR-ASBT cascade reaction, centered around bile acid receptor FXR, plays a pivotal role in maintaining bile acid metabolic homeostasis to prevent the occurrence and progression of ulcerative colitis (UC).
View Article and Find Full Text PDFObjective: Guanyu Zhixie Granule (GYZXG) is a traditional Chinese medicine compound with definite efficacy in intervening in gastric ulcers (GUs). However, the effect mechanisms on GU are still unclear. This study aimed to explore its mechanism against GU based on amalgamated strategies.
View Article and Find Full Text PDFis the aboveground stem part of the Thunb, which belongs to the medicine food homology species in China. It has the effects of clearing away heat, toxic material, dredging wind and unblocking collaterals. Modern research shows that it contains various active metabolites and a wide range of pharmacological effects, which is of great research and clinical application value.
View Article and Find Full Text PDFDriven by precursor emissions, meteorological conditions, and other factors, atmospheric ozone (O) has become the main pollutant affecting urban air quality in summer. The current deductive models driven by physical and chemical mechanisms require a large number of parameters for the analysis of O pollution, and the calculation timeliness is poor. The data-driven inductive models are efficient but have problems such as poor explanation.
View Article and Find Full Text PDFThe cover-time problem, i.e., the time to visit every site in a system, is one of the key issues of random walks with wide applications in natural, social, and engineered systems.
View Article and Find Full Text PDFThe exhaustive random exploration of a complex domain is a fundamental issue in many natural, social, and engineering systems. The key characterizing quantity is the cover time, which is the time to visit every site in the system. One prototypical experimental platform is the confined granular gas, where the random motion of granular particles mimics the wandering of random walkers in a confined region.
View Article and Find Full Text PDFAn SBA-15 loaded CuSO catalyst was designed and prepared for the highly selective production of 2,6-di--butyl--cresol (BHT) from -cresol and isobutylene. The acidity of solid acid catalysts was altered by varying the loading amount of CuSO. Among them, 10% CuSO/SBA-15 exhibited the greatest catalytic performance in the alkylation reaction with a BHT yield of 85.
View Article and Find Full Text PDFBoolean networks introduced by Kauffman, originally intended as a prototypical model for gaining insights into gene regulatory dynamics, have become a paradigm for understanding a variety of complex systems described by binary state variables. However, there are situations, e.g.
View Article and Find Full Text PDFBackground: Neuromedin U (NMU) plays an important role in activating the group 2 innate lymphoid cells (ILC2s) and initiating the host's anti-parasitic immune responses. It is aimed to explore the distribution characteristics of NMU in the sheep small intestine and the influence of Moniezia benedeni infection on them. In the present study, the pET-28a-NMU recombinant plasmids were constructed, and Escherichia coli.
View Article and Find Full Text PDFIn order to explore the impacts of the land use conversion from a (moso bamboo) forest to a cv. Merrillii plantation, as well as the cultivating years of the cv. Merrillii plantation, on the soil microbial community, this research studied the soil microbial structure and diversity of a moso bamboo forest, cv.
View Article and Find Full Text PDFBackground: Exposure to glyoxal, the smallest dialdehyde, is associated with several diseases; humans are routinely exposed to glyoxal because of its ubiquitous presence in foods and the environment. The aim of this study was to examine the damage caused by glyoxal in human aortic endothelial cells.
Methods: Cell survival assays and quantitative fluorescence assays were performed to measure DNA damage; oxidative stress was detected by colorimetric assays and quantitative fluorescence, and the mitogen-activated protein kinase pathways were assessed using western blotting.
Spatially distinct, self-sustained oscillations in artificial neural networks are fundamental to information encoding, storage, and processing in these systems. Here, we develop a method to induce a large variety of self-sustained oscillatory patterns in artificial neural networks and a controlling strategy to switch between different patterns. The basic principle is that, given a complex network, one can find a set of nodes-the minimum feedback vertex set (mFVS), whose removal or inhibition will result in a tree-like network without any loop structure.
View Article and Find Full Text PDFThe second law of thermodynamics states that the entropy never decreases for isolated macroscopical systems, which defines the arrow of time. For small systems, although the entropy increases on average, due to strong fluctuation, it may encounter a temporary decrease. The probability of negative entropy production follows the fluctuation theorem.
View Article and Find Full Text PDFEthnopharmacological Relevance: Sophora alopecuroides L. is one of the most commonly used plants in traditional medicine for the management conditions including inflammatory and gastrointestinal disease. However, the therapeutic mechanism of Sophora alopecuroides L.
View Article and Find Full Text PDFThe main point of this paper is to provide an affirmative answer through exploiting reinforcement learning (RL) in artificial intelligence (AI) for eliminating herding without any external control in complex resource allocation systems. In particular, we demonstrate that when agents are empowered with RL (e.g.
View Article and Find Full Text PDFClique percolation has attracted much attention due to its significance in understanding topological overlap among communities and dynamical instability of structured systems. Rich critical behavior has been observed in clique percolation on Erdős-Rényi (ER) random graphs, but few works have discussed clique percolation on finite dimensional systems. In this paper, we have defined a series of characteristic events, i.
View Article and Find Full Text PDFJ Huazhong Univ Sci Technolog Med Sci
August 2015
Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a serious health issue, which can impact the hormone secretion. The aim of this study is to analyze the relationship between serum sex hormone concentrations and different severity degree of OSAHS, and to evaluate the influence of OSAHS on sex hormone levels. We enrolled 116 subjects who were subjected to polysomnography (PSG).
View Article and Find Full Text PDFPhys Rev E Stat Nonlin Soft Matter Phys
December 2014
Dynamical systems based on the minority game (MG) have been a paradigm for gaining significant insights into a variety of social and biological behaviors. Recently, a grouping phenomenon has been unveiled in MG systems of multiple resources (strategies) in which the strategies spontaneously break into an even number of groups, each exhibiting an identical oscillation pattern in the attendance of game players. Here we report our finding of spontaneous breakup of resources into three groups, each exhibiting period-three oscillations.
View Article and Find Full Text PDFThe relation between flux and fluctuation is fundamental to complex physical systems that support and transport flows. A recently obtained law predicts monotonous enhancement of fluctuation as the average flux is increased, which in principle is valid but only for large systems. For realistic complex systems of small sizes, this law breaks down when both the average flux and fluctuation become large.
View Article and Find Full Text PDFPhys Rev E Stat Nonlin Soft Matter Phys
May 2013
Resource allocation takes place in various kinds of real-world complex systems, such as traffic systems, social services institutions or organizations, or even ecosystems. The fundamental principle underlying complex resource-allocation dynamics is Boolean interactions associated with minority games, as resources are generally limited and agents tend to choose the least used resource based on available information. A common but harmful dynamical behavior in resource-allocation systems is herding, where there are time intervals during which a large majority of the agents compete for a few resources, leaving many other resources unused.
View Article and Find Full Text PDFComplex systems arising in a modern society typically have many resources and strategies available for their dynamical evolutions. To explore quantitatively the behaviors of such systems, we propose a class of models to investigate Minority Game (MG) dynamics with multiple strategies. In particular, agents tend to choose the least used strategies based on available local information.
View Article and Find Full Text PDFZhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
February 2012
Objective: To compare the operative effectivity and incidence of postoperative complication between conventional uvulopalatopharyngoplasty (UPPP) and modified coblation assisted UPPP (M-CAUP) in treating patients with obstructive sleep apnea-hypopnea syndrome (OSAHS). And to explore the more effective, safer and minimally invasive operative method in surgical therapy of OSAHS.
Methods: It was a controlled trial.