[Randomized double-blind placebo-controlled trial of Jingfang Granules in treatment of common cold(wind-cold syndrome)].

Jingfang Granules have the effects of inducing sweating to releasing exterior, dispersing wind and dispelling dampness. Modern studies have demonstrated that it has antipyretic and antiviral activities. Therefore, this trial was conducted to evaluate the efficacy and safety of Jingfang Granules in the treatment of common cold(wind-cold syndrome).

Impact of combination use of 0.004% travoprost and 2% pilocarpine on matrix metalloproteinases synthesized by rabbit ciliary muscle: a pilot study.

Objective: To explore the impact of combination use of prostaglandin analogue and cholinergic agonists on main matrix metalloproteinases (MMPs) synthesized by albino rabbit ciliary muscle.

Methods: Normal adult albino rabbits were divided into the control group, 2% pilocarpine group, 0.004% travoprost group and travoprost plus pilocarpine group.

[Prevalence and causes of blindness and moderate and severe visual impairment among adults aged 50 years or above in Luxi County of Yunnan Province: the China Nine-Province survey].

Objective: To investigate the prevalence and causes of blindness and moderate and severe visual impairment among adults aged ≥ 50 years in Luxi County of Yunnan Province, China.

Methods: It was a population-based cross-section study. Geographically defined cluster sampling was used in randomly selecting 5575 individuals aged ≥ 50 years in Luxi County.

[Prevalence and causes of blindness and moderate and severe visual impairment among adults aged 50 years or above in Changji City of Xinjiang Uygur Autonomous Region: the China Nine-Province survey].

Objective: To investigate the prevalence and causes of blindness and moderate and severe visual impairment among adults aged ≥ 50 years in Changji City of Xinjiang Uygur Autonomous Region, China.

Methods: It was a population-based cross-section study.Geographically defined cluster sampling was used in randomly selecting 5714 individuals aged ≥ 50 years in Changji City.

[Prevalence and causes of blindness and moderate and severe visual impairment among adults aged 50 years or above in Longyao County of Hebei Province:the China Nine-Province survey].

Objective: To investigate the prevalence and causes of blindness and moderate and severe visual impairment among adults aged ≥ 50 years in Longyao County, Hebei Province, China.

Methods: It was a population-based cross-section study.Geographically defined cluster sampling was used in randomly selecting 5527 individuals aged ≥ 50 years in Longyao County.

[Prevalence and causes of blindness and moderate and severe visual impairment among adults aged 50 years or above in Yongchuan District of Chongqing City: the China Nine-Province survey].

Objective: To investigate the prevalence and causes of blindness and moderate and severe visual impairment among adults aged 50 years or above in Yongchuan of Chongqing City, China.

Methods: It was a population-based cross-section study.Geographically defined cluster sampling was used in randomly selecting 5663 individuals aged ≥ 50 years in Yongchuan District.

[Overall and intensively conduct the prevention of blindness in China: explaining the National Plan for the Prevention of Blindness (2012-2015)].

The National Plan for the Prevention of Blindness(2012-2015) issued by Ministry of Health and China Disabled Person Federation last year is an important procedure for further promoting the prevention of blindness and reach the great goal for eliminating the avoidable blindness by 2020 in China. The Plan clearly describe the social nature of the prevention of blindness, correctly explain the current situation for prevention of blindness in China, put forward the guidance idea, working principles, goals and contents, and the guarantee measures in the next four years in the prevention of blindness in China. The leaders in ophthalmology and ophthalmologists in China should learn and practice the Plan for the more progress in the prevention of blindness.

[Expressions of vascular endothelial growth factor and its receptors in rat conjunctival fibroblasts].

Objective: To detect the expressions of vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptors (VEGFR) in cultured rat conjunctival fibroblasts.

Methods: Experimental study. Conjunctiva was obtained from each eye of five Sprague Dawley (SD) rats under local anesthesia.

[Expression of Nogo-A, NgR mRNA and protein in the retina of rats with chronic elevated intraocular pressure].

Objective: To investigate the expression of Nogo-A and its receptor NgR mRNA and protein in the retina of rats with chronic elevated intraocular pressure (IOP).

Methods: Experimental study. Rat chronic ocular hypertension (OHT) was induced by obstructing episcleral veins and temporal limber veins.

[Contrast visual acuity in adults with normal visual acuity].

Objectives: To evaluate the contrast visual acuity (CVA) in Chinese normal adults and to study the effects of different contrast levels between the optotypes and background, age and sex on the CVA.

Methods: It was a cross-sectional study. Three hundreds and fifty-three normal adults with age from 20 to 70 years were selected as the normal adults (naked visual acuity equal or more than 0.

[Prevalence and surgery status of cataract among adults aged 50 years or above in Qidong City of Jiangsu Province: the China Nine-Province Survey].

Objective: To estimate the prevalence of cataract, the rate of cataract surgical coverage rate,and the rate of cataract-blindness social burden among older adults aged 50 years or above in Qidong City of Jiangsu Province, China, in 2006.

Methods: Cluster sampling was used in randomly selected 5662 individuals aged 50 years or above in 16 clusters in Qidong City. 5141 individuals received visual acuity and eye examination from September to December 2006.

[Prevalence and surgery status of cataract among adults aged 50 years or above in the Shunyi district of Beijing: the China Nine-Province Survey].

Objective: To assess the prevalence of cataract, the outcomes of cataract surgery, the rate of cataract surgical coverage, and the rate of cataract blindness social burden.

Methods: Cluster sampling was used in 5118 randomly selected individuals aged > or = 50 years in the Shunyi district of Beijing from April to August 2006. All individuals were received visual acuity and eye examination, including the evaluation of lens status and cataract surgical status by slit lamp biomicroscopy.

[Prevalence of blindness and moderate and severe visual impairment among adults aged 50 years or above in Qidong City of Jiangsu Province: the China Nine-Province Survey].

Objective: To estimate the prevalence of blindness and low vision among older adults aged > or = 50 years in Qidong City of Jiangsu Province, China, in 2006.

Methods: Cluster sampling was used in randomly selecting 5662 individuals aged > or = 50 years from September to December 2006 in 16 clusters in Qidong City. The survey was preceded by a pilot study where operational methods were refined and quality assurance evaluation was carried out.

[Prevalence of blindness and moderate and severe visual impairment among adults aged 50 years or above in the Shunyi District of Beijing: the China Nine-Province Survey].

Unlabelled: OBJECTIVE To assess the prevalence of blindness and moderate and severe visual impairment among adults aged 50 years or above in the Shunyi district of Beijing,China.

Methods: It was a population-based cross-section study. Geographically defined cluster sampling was used in 5840 randomly selected individuals aged > or = 50 years in 28 clusters in the Shunyi district from April to August 2006.

[Prevention of blindness is still an arduous task and embarks on a long road in China].

The outcomes from China Nine-Province Survey shows that the prevention of blindness in China have got some achievements, however, the status of blindness and moderate and severe visual impairment is still serious. The prevalence of blindness and moderate and severe visual impairment in some remote areas is higher than the national average level. The major cause of blindness and visual impairment is cataract,however, retinal diseases are found to be the second major cause, which reflects both characteristics of blindness in the developed and developing countries.

[Novel exploration of emergency treatment for ueitic acute angle closure glacuma].

Objective: To explore the effects of anterior chamber paracentesis plus pupillary block relief under slit-lamp microscope for the emergency treatment of uveitic acute angle closure glaucoma (ACG).

Methods: In early stage, 14 uveitc acute ACG patients received anterior chamber paracentesis plus pupillary block relief while another 10 uveitc acute ACG patients underwent laser peripheral iridectomy (LPI). The intraocular pressure (IOP), degree of Tyndall, degree of pupillary block and severe adverse events were recorded at each observation timepoint.

[Analysis of optical coherence tomography in early stage of optic neuritis in multiple sclerosis patients].

Objective: To detect the changes in the retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) in the eyes of multiple sclerosis patients during the early stage of optic neuritis.

Methods: A prospective case series study. Suspected acute optic neuritis of multiple sclerosis (MS) patients who attended the department of ophthalmology in Peking Union Medical College hospital from Feb.

[Sampling and measurement methods of the protocol design of the China Nine-Province Survey for blindness, visual impairment and cataract surgery].

Objective: To design the protocol of the China nine-province survey for blindness, visual impairment and cataract surgery to evaluate the prevalence and main causes of blindness and visual impairment, and the prevalence and outcomes of the cataract surgery.

Methods: The protocol design was began after accepting the task for the national survey for blindness, visual impairment and cataract surgery from the Department of Medicine, Ministry of Health, China, in November, 2005. The protocol in Beijing Shunyi Eye Study in 1996 and Guangdong Doumen County Eye Study in 1997, both supported by World Health Organization, was taken as the basis for the protocol design.

[To promote "Vision 2020" Initiative under the new situation in China].

At present, the prevention of blindness in China is in the favorable period and got some important progress. Recent five years, Chinese government conducted a series of the program for prevention of blindness, cataract surgical rate is increasing. The reform of the medical system conducted by the government is favorable to the prevention of blindness.

Comparative efficacy and safety of the fixed versus unfixed combination of latanoprost and timolol in Chinese patients with open-angle glaucoma or ocular hypertension.

Background: A noninferiority trial was conducted to evaluate the efficacy of a single evening dose of fixed-combination latanoprost 50 μg/mL and timolol 0.5 mg/mL (Xalacom®; LTFC), in Chinese patients with primary open-angle glaucoma (POAG) or ocular hypertension (OH) who were insufficiently controlled on β-blocker monotherapy or β-blocker-based dual therapy.

Methods: This 8-week, randomized, open-label, parallel-group, noninferiority study compared once-daily evening dosing of LTFC with the unfixed combination of latanoprost, one drop in the evening, and timolol, one drop in the morning (LTuFC).

Cytomegalovirus retinitis associated with acquired immunodeficiency syndrome.

Background: Cytomegalovirus (CMV) retinitis is the most severe intraocular complication that results in total retinal destruction and loss of visual acuity in patients with acquired immunodeficiency syndrome (AIDS). This study aimed to investigate the fundus characteristics, systemic manifestations and therapeutic outcomes of CMV retinitis associated with AIDS.

Methods: It was a retrospective case series.

[To construct the national system for the management of glaucoma].

It is important and necessary to strength the prevention and treatment of glaucoma, since glaucoma is a serious irreversible blinding disease. Although we have done a lot of works in the prevention and treatment of glaucoma in China, there still exist some problems as follows: prevention and treatment of glaucoma have not been taken as the priority in the prevention of blindness, the national ranks and organizations for the prevention and treatment of glaucoma have not been established, the knowledge on glaucoma has not been popularized and updated in ophthalmologists, the supply network of glaucoma medicine has not been organized, the knowledge for prevention of glaucoma has not been disseminated in the public. For settling these problems, we should construct the national system for the management of glaucoma.